AI analysis of healthcare records reveals key factors in autism diagnosis
Scientists argue the criteria we use for diagnosing autism may need revisionWithout clear and effective biological tests for autism based on genes, brain or blood measurements, diagnosis today still largely depends on clinical assessment. The standard way of doing this is by observing how the individual fits the criteria for autism listed in gold standard manuals like the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5).
Expanding access to specialized healthcare across Quebec: ECHO Superhub at The Neuro
Free, online training program strengthens training and brings specialized care to communities across QuebecA healthcare telementoring program housed at The Neuro and supported by the Transforming Autism Care Consortium (TACC) is expanding its reach after achieving designation as an ECHO Superhub.
Latest Alzheimer’s drug shown less effective in females than males
Since becoming only the second Alzheimer’s-modifying drug to gain American FDA approval in 2023, sales of lecanemab, known by its brand name Leqembi, have risen steadily, reaching $87-million USD in the last quarter of 2024.
Genetic sequencing project receives more than $8 million in funding
NeuRo Genomics Initiative will help better understand rare and aging-related neurological disorders affecting Canadians
A project led by Ziv Gan-Or, MD, PhD, at The Neuro (Montreal Neurological Institute-Hospital) of McGill University and Martine Tétreault, PhD, at Université de Montréal has received more than $8 million to sequence the genomes of 8,700 people, to map the role of genetics in neurological disorders.
Project to create AI model for ALS receives Génome Québec funding
$400,000 will fuel public-private collaboration to discover new disease biomarkers
Achievements of clinicians and scientists recognized with King Charles III Coronation Medals
Five clinicians and scientists at The Neuro have been awarded King Charles III Coronation Medals in recognition of their contributions to our understanding of neurological disease. The Coronation Medal commemorates the Coronation of His Majesty King Charles III as King of Canada. The medal is administered by the Chancellery of Honours at Rideau Hall.
Prescribing anti-swelling drug reduces immune response weeks after last dose
Mapping immune cell diversity reveals dexamethasone’s impact on brain cancer immunotherapy
Swelling caused by brain cancer is a problem that can lead to serious side effects and even death. While controlling swelling is important, a new study shows that a commonly prescribed anti-swelling drug suppresses the immune system for weeks after dosage, inhibiting the body’s ability to fight the cancer.
Six principal investigators from The Neuro receive CIHR grants
Projects include important research on Parkinson’s, glioblastoma and dementia
An open solution to improving research reproducibility
Academic and industry scientists collaborate on a new method to characterize research antibodiesStructural Genomics Consortium researchers at The Neuro (Montreal Neurological Institute-Hospital) of McGill University, in collaboration with scientists from 11 major antibody manufacturers representing approximately 80 per cent of global renewable antibody production, have developed and standardized an Open Science platform to characterize research antibodies.
Open Science project funded for $1.5M
YCharOS antibody characterization platform addresses the “reproducibility crisis” in researchAn innovative research project led by researchers at The Neuro has been awarded $1.5M by the Government of Quebec through CQDM.
YCharOS is an innovative platform led by neuroscientists Peter McPherson and Carl Laflamme that validates antibody reagents for human proteins.
At-home neurological disorder diagnosis project receives major funding
$1M grant from The Weston Family Foundation will pave the way for earlier intervention in REM sleep behaviour disorder and Parkinson’s diseaseREM sleep behaviour disorder (RBD) is an often debilitating condition that causes people to act out in their sleep, sometimes violently. What’s worse, people with the disorder often go on to develop Parkinson’s disease.
Gene therapy project receives major funding
$1.14 million from CIHR will resolve treatment roadblocks for rare brain disorders
Gene therapy for rare neurological disorders will move one step forward thanks to a $1.14 million grant from the Canadian Institutes of Health Research (CIHR).
Research on new stem cell models receives $2.6 million
Thomas Durcan’s project will dissect the role of microglia in degenerative conditions, to identify new therapeutic strategies for Alzheimer's treatmentAn innovative new program based at The Neuro has received $2.6 million from the CQDM and the Brain Canada Foundation.
Bilingualism makes the brain more efficient, especially when learned at a young age
MRI data from large sample shows increased whole-brain connectivity in people with a second languageNeuroplasticity is the brain’s ability to build connections within itself, adapting to the surrounding environment. The brain is most plastic in childhood, forming new pathways in reaction to stimuli such as language.
Recreating a hallmark of Parkinson's disease in human neurons
Scientists use stem cells to follow development of protein bodies characteristic of neurological diseaseLewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.
