Researchers at Early Drug Discovery Unit

Early Drug Discovery Unit (EDDU)

Making connections:

Accelerating drug discovery
to improve the lives of people with neurological disease

35+Team members75+Users trained45+Academic collaborators8Industry partners

OUR MISSION

  1. Train the next generation of researchers to work with induced pluripotent stem cells (iPSCs)

  2. Translate fundamental research and technology into industry-standard assays

  3. Identify new and improved treatments for neurological disorders

WHAT WE DO

  • Collaborate with academic and industry partners to develop new Open Science tools and technologies that use iPSCs

  • Specialize in research using iPSCs and iPSC-derived cells

  • Combine expertise in patient-derived stem cells, assay development, and automated high-content screening

  • Offer iPSC-related training and protocols developed by our researchers

 


WORKING GROUPS

Our team is made up of four working groups that each focus on a different area of research.

iPSC phenotyping and CRISPR editing


Meet Carol


We are developing a library of iPSC lines in partnership with the C-BIG Repository for a variety of applications. We have expertise in:

  • iPSC phenotyping
  • CRISPR editing
  • Antibody Validation and CRISPR knockout (KO)

Researchers: Learn more

Discovery assays and screens


Meet Wolfgang


We translate fundamental research into industry-standard cell-based assays and small molecule screens. Our focus includes:

  • Parkinson's Disease and synucleinopathies
  • ALS and neuromuscular disorders
  • Neurodevelopmental disorders
  • Small molecule screening and automated image analysis

Researchers: Learn more

Organoids and tissue engineering


Meet Meghna


We develop neuronal organoids, also known as 'mini brains', which are miniature 3D models of the brain created from iPSCs. Our organoid program offers:

  • Organoid maintenance and quality control
  • 3D model development
  • Histology and 3D imaging
  • Single cell phenotyping

Researchers: Learn more

Training and outreach


Meet Rozzy

We are sharing our experiences with iPSCs and engaging with research communities in many ways:

  • “Introduction to iPSCs” hands-on workshops
  • One-on-one, hands-on training
  • Open protocols
  • iPSC Seminar Series

Researchers: Learn more


Tags: 

JOIN THE MOVEMENT

Researchers gather around laptop to share information

We are part of Open Science at The Neuro

We believe in freely sharing data and materials to speed up drug discovery and engage in the following Open Science activities:

  1. Open data - Publishing in open-access journals
  2. Open access - Sharing protocols and providing training
  3. Open intellectual property - Promoting open partnerships with industry
  4. Open sharing - Making our reagents available

Take action today: 

EDDU ON TWITTER

CONNECT WITH US

Email or call us to schedule a visit of the EDDU and to meet the team.

Early Drug Discovery Unit
The Neuro
3801 University
North Wing B150
Montreal, QC H3A 2B4
514-398-7298 
neuroeddu.mni [at] mcgill.ca (subject: Website%20Enquiry%3A%20Interested%20in%20visiting%20Neuro%20EDDU) (Email us)

Entrance to EDDU at 3801 University

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Collaborate

Interested in partnering with us? neuroeddu.mni [at] mcgill.ca (Email us) 

Join

Want to join our team? Visit Neuro Careers for available positions.

For undergraduate positions, please email neuroeddu.mni [at] mcgill.ca (Lenore Beitel).

Support

If you would like to support our work, visit Neuro Giving for more information.

Get involved

Want to get involved? neuroeddu.mni [at] mcgill.ca (Email us) to find out how you can: 

  • Develop your own Open Lab Notebook
  • Create your own iPSC protocol
  • Build new software for analyzing iPSCs and iPSC-derived neurons
  • Give a talk at our iPSC Seminar Series

 

The Neuro logo McGill logoMcGill University Health Centre logoKillam logo

The Neuro is a McGill research and teaching institute; delivering the highest quality patient care, as part of the Neuroscience Mission of the McGill University Health Centre. We are proud to be a Killam Institution, supported by the Killam Trusts.