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iPSC Culture Protocol Videos
Watch our iPSC culture protocol videos to learn how to culture iPSCs and iPSC-derived neural cells.
English, French, Portuguese, and Spanish videos are available now, with more languages coming soon!
At the EDDU, we developed a method with microfabricated disk (EB disk-948 from eNUVIO) to scale up the generation of hMOs (human midbrain organoids). This opens up the possibility to generate larger numbers of hMOs, in a manner that minimizes the amount of labor required, while decreasing variability and maintaining the viability of these hMOs over time.
This video will describe the methodology to generate hMOs from a single EB-Disk containing 948 microwells.
The Neuro’s EDDU is also pleased to share our updated protocol for generating dopaminergic neurons from iPSCs through the use of a Microfabricated EB Disk. You can access the protocol here: https://zenodo.org/record/8256637
Latest Publications
To access all of the EDDU's publications, please visit our Community and Resource Hub.
Single Cell RNAseq to identify subpopulations of glial progenitors in iPSC-derived oligodendroglial lineage cultures
April 2025
Gabriela J Blaszczyk et al.
Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase
July 2025
Fabienne C Fiesel et al.
Preprints
Midbrain organoids with an SNCA gene triplication display dopamine-dependent alterations in network activity
April 2025
Ghislaine Deyab et al.
BetaII-Spectrin Gaps and Patches Emerge from the Patterned Assembly of the Actin/Spectrin Membrane Skeleton in Human Motor Neuron Axon
July 2025
Nahir Guadalupe Gazal et al.
How to Access iPSCs
At the EDDU we have a catalogue of iPSC lines from healthy individuals and from patients with neurological disorders that can be freely accessed for a small fee. Our cells are for experimental use only.
How to access the iPSC catalogue:
- Click “Open data access” as login
- Select at the top-left “Open data” tab
- Click “iPSC catalogue”
To access the cells, please cbig.mni [at] mcgill.ca (C-BIG). Click here for further instructions on accessing cells.
To learn more about how the cells are made or for general inquiries, please email xiuqing.chen [at] mcgill.ca (Carol Chen) and taylor.goldsmith [at] mcgill.ca ( Taylor Goldsmith).
Visit our Community and Resource Hub
To access the EDDU’s Open Science resources including our publications, presentations, protocols, and software please visit our Community and Resource Hub.
Access The Neuro EDDU Community and Resource Hub
