Killam Seminar Series: Molecular Mechanisms of Selective Neuronal Resilience and Axon Regeneration

Tuesday, April 30, 2024 16:00to17:00
Montreal Neurological Institute de Grandpre Communications Centre, 3801 rue University, Montreal, QC, H3A 2B4, CA

Supported by the generosity of the Killam Trusts, The Neuro's Killam Seminar Series invites outstanding guest speakers whose research is of interest to the scientific community at the MNI and McGill University.

To attend in person, register here

To watch via vimeo, click here

Nicholas Tran, PhD

Assistant Professor, Department of Molecular and Human Genetics, Baylor College of Medicine, USA

Host: alyson.fournier [at] mcgill.ca (Alyson Fournier)

Abstract: In all neurodegenerative conditions, some neurons are more affected or degenerate earlier than others, this is a phenomenon called selective vulnerability. So why do some neurons die, while others are resilient to the same injury or condition? Our lab uses the retina as an approachable system to investigate the cellular mechanisms that underlie type-specific resilience to axonal damage. I will introduce how we have been using single-cell genomic approaches to parse how different retinal cell types are affected by injury and how they respond to different interventions. Our work reveals endogenous mechanisms that support neuronal survival and axon growth, which can be leveraged to develop novel neuroprotective and regenerative treatments.

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The Neuro (Montreal Neurological Institute-Hospital) is a bilingual academic healthcare institution. We are a McGill research and teaching institute; delivering high-quality patient care, as part of the Neuroscience Mission of the McGill University Health Centre. We are proud to be a Killam Institution, supported by the Killam Trusts.



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