Feindel Brain and Mind Lecture Series: REM sleep behavior disorder: A window into early neurodegeneration

Wednesday, October 26, 2022 16:00to17:00
Montreal Neurological Institute De Grandpre Communications Center, 3801 rue University, Montreal, QC, H3A 2B4, CA

The Feindel Virtual Brain and Mind Seminar presents: "REM sleep behavior disorder: A window into early neurodegeneration"

Shady Rahayel, Postdoctoral researcher, The Neuro

Abstract: Sleep paralysis is a normal feature of REM sleep. However, some people lose this muscle atonia and start acting out their dreams, a parasomnia called REM sleep behavior disorder (RBD). RBD is recognized as a strong marker of an incipient synucleinopathy, with the vast majority of patients developing dementia with Lewy bodies or Parkinson’s disease. In this talk, I will highlight my research work in the field of brain imaging and computational neuroscience in isolated RBD. Specifically, this talk will dive into the prodromal brain changes associated with isolated RBD and focus on how observations of brain atrophy can be used to predict disease progression and uncover some of the mechanistic bases of neurodegeneration in synucleinopathies.

Bio: Shady Rahayel is a postdoctoral researcher specialized in brain imaging, sleep, and neurodegenerative disorders. After a first postdoctoral training in molecular imaging at the University of Montreal, he is now a postdoctoral researcher at The Neuro in the lab of Alain Dagher working on RBD and brain imaging. Shady was also trained as a neuropsychologist specialized in geriatrics and currently practices as a clinical sleep psychologist. In 2023, he will officially start his own lab at the Center for Advanced Research in Sleep Medicine and at the Department of Medicine of the University of Montreal, focusing on brain imaging and sleep disorders.

The Feindel Virtual Brain and Mind (VBM) Seminar Series will advance the vision of Dr. William Feindel (1918–2014), Former Director of the Neuro (1972–1984), to constantly bridge the clinical and research realms. The talks will highlight the latest advances and discoveries in neuropsychology, cognitive neuroscience, and neuroimaging.

Speakers will include scientists from across The Neuro, as well as colleagues and collaborators locally and from around the world. The series is intended to provide a virtual forum for scientists and trainees to continue to foster interdisciplinary exchanges on the mechanisms, diagnosis and treatment of brain and cognitive disorders.

To watch via Vimeo, click here.

** Refreshments will be served

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The Neuro (Montreal Neurological Institute-Hospital) is a bilingual academic healthcare institution. We are a McGill research and teaching institute; delivering high-quality patient care, as part of the Neuroscience Mission of the McGill University Health Centre. We are proud to be a Killam Institution, supported by the Killam Trusts.



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