Madeleine Sharp: I choose The Neuro

Dr. Madeleine Sharp is a neurologist specializing in movements disorders. Her research focuses on understanding the cognitive mechanisms that underlie the cognitive dysfunction in patients with movement disorders.

Movement disorders that affect the basal ganglia, such as Parkinson’s and Huntington’s disease, are increasingly recognized as impairing much more than movement. Cognitive and behavioral symptoms are very common in these patients but remain poorly understood and difficult to treat. Her lab’s research aims to relate what we know about the role of the basal ganglia in healthy cognition to patients’ common cognitive symptoms such as executive dysfunction, difficulty in multi-tasking and apathy.

Examples of current projects include examining the role of the basal ganglia in orienting learning and memory towards motivationally significant goals, and examining the role of disturbed sleep in long-term memory in Parkinson’s patients. Her research combines behavioral experiments, pharmacological manipulations and neuroimaging in patients and healthy populations. Ultimately, the goal is to develop more precise models of cognitive dysfunction in patients, grounded in neurobiology, in order to develop and to reliably test novel behavioral and pharmacologic therapies.

 

GET OUR NEWSLETTER

 

The Neuro logo McGill logoMcGill University Health Centre logoKillam Laureates

 

The Neuro (Montreal Neurological Institute-Hospital) is a bilingual academic healthcare institution. We are a McGill research and teaching institute; delivering high-quality patient care, as part of the Neuroscience Mission of the McGill University Health Centre. We are proud to be a Killam Institution, supported by the Killam Trusts.

 

 

Facebook instagram x, formerly known as twitter linkedIn youtube

Back to top