Nicholas Makhoul

Academic title(s): 

Associate Professor
Associate Dean of Postgraduate Dental Education; 
Chief of Dentistry, Montreal General Hospital

Nicholas Makhoul
Contact Information
Email address: 
nicholas.makhoul [at]

Nicholas Makhoul is dual degreed and boarded Oral and Maxillofacial Surgeon with sub-specialization in Maxillofacial Oncology and Microvascular Reconstructive Surgery.  He received his BSc with distinction from the University of Alberta in Biochemistry, DMD at McGill University and his MD at the University of Michigan.  He completed his clinical residency training in Oral and Maxillofacial Surgery at the University of Michigan. After residency he also completed an accredited fellowship in Maxillofacial Oncology and Microvascular Surgery at the University of Michigan. He is situated at the Montreal General Hospital and is director of the McGill Oral and Maxillofacial Residency Program and a practicing academic maxillofacial surgeon. 

His research interests include the use of tissue engineering principles to achieve functional and esthetic reconstructions in patients that are missing hard and soft tissue after tumor ablation, trauma or congenital deformities.    Focusing on forming collaborations with researchers from different disciplines and fields to achieve novel techniques in composite tissue engineering.  Additionally, Dr. Makhoul has a CAOMS grant to develop an oral oncology database, collaborating with specialists in bio-statistics and epidemiology.   The aim of this large scale database will be to assess outcomes in maxillofacial oncology patients as well as to identify factors that contribute to increased quality and quantity of life, with the aim of developing future randomized controlled trials based on variables identified in our database.

In his role as Associate Dean of Postgraduate Dental Education, Dr. Makhoul is responsible for overseeing all academic post-graduate dental programs (i.e. dental residency programs). He helps coordinate programs between different residency sites and disciplines. He is also available to work with residency program directors to ensure that residents are receiving a high quality education in an environment conducive to learning.

Research areas: 
Population Oral Health
Selected publications: 

Virtual Surgical Planning and Stereolithography-guided Osteotomy for 3 Dimensional Mandbular Reconstruction with Free Fibula Osseous Flaps: A Case Report Woong N, Makhoul NM, Ward B, Helman JI, Edwards SP. Journal of Korean Association of Maxillofacial Plastic and Reconstructive Surgery, 2012;34(5):337-342

Book Chapter: Clinical Correlates: Osteoradionecrosis of the Jaw (ORN). Makhoul, NM, Ward, BB. Mineralized Tissues in Oral and Craniofacial Science, 2012 Laurie K. McCauley and Martha J. Somerman

Book Chapter: Oral Cancer Diagnosis and Treatment Makhoul NM, Ward BB. Oral and Maxillofacial Surgery Knowledge Updates: (In Press)

Book Chapter: The latissums dorsi free flap. Makhoul NM, Atlas of Oral and Maxillofacial Surgery: 2013 (In Press)

Development of a Microcapillary System for Tissue Engineering, Makhoul, NM; Zussman E; Zhang W; Srouji S; Feinberg S Journal of Oral and Maxillofacial Surgery, Volume 66, Issue 8, Pages 45-46

Preoperative evaluation of lower extremities prior to Fibular Flap Transfer. Makhoul NM, Ward, BB, Helman, JI, Edwards, SP. Journal of Oral and Maxillofacial Surgery, Vol. 69, Issue 9, Supplement, Pages e106-e107

Functional Reconstruction of a Complex Bilateral Atrophic Edentulous Mandibular Fracture with Continuity Defects using Computational Planning and Free Fibular Transfer.  Makhoul NM, Ward BB, Edwards SP. International Journal of Oral and Maxillofacial Surgery

Autogenous Onlay Bone Grafts to the Mandible: A Prospective Experimental Evaluation of Graft Cellularity and Embryonic Origin. El-Hakim, M; Makhoul, NM; Head, TW
Presented at the 2004 Canadian Association of Oral and Maxillofacial Surgery Conference Quebec City, Quebec.

Autogenous Onlay Bone Grafts to the Mandible: A Prospetive Experimental Evaluation of Graft Cellularity and Embryonic Origin Part 2.  El- Hakim M, Head, TW, Makhoul NM, Al Harkan, A.
Presented at 2006 Canadian Association of Oral and Maxillofacial Surgery Conerfence Montreal Quebec. 

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