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Standard Operating Procedures (SOPs) provide a detailed description of commonly used procedures. SOPs offer investigators an alternative to writing detailed procedures in their protocol. Any deviation from the approved procedures must be clearly described and justified in the Animal Use Protocol application in Darwin. Approval of the protocol indicates approval of the deviation from the SOP for that project only.
The following Standard Operating Procedures (SOPs) were created and/or revised by the Veterinary committee and/or the Occupational Health and Safety Working Group, and approved by the Animal Policy and Welfare Oversight Committee (APWOC). They are reviewed every 3 years at most. The month and year appearing in the file name indicate when that SOP last underwent changes. Starting in 2020, the date of last review will now be specified inside the SOP even if no changes were made to it.
If you have questions or have a recommendation to make, please send an animalcare [at] mcgill.ca (email) or talk to the Veterinarian in your area.
DRAFT SOP FOR APWOC REVIEW UNTIL AUGUST 28, 2021:
DRAFT SOP FOR APWOC REVIEW UNTIL AUGUST 12, 2021:
Note that the SOP #416 Social Defeat is currently undergoing revisions again. Once done, it will be re-posted for review.
APPROVED SOPS BELOW:
SOP 401- Controlled Drugs - Jan 2020 <- includes a log at the end
This Monitoring Log is to be prepared by the Facility Animal Care Committee as per the approved Animal Use Protocol: Monitoring log TEMPLATE - Oct 2017
Metastatic Model Monitoring log <- is a log
Tumor Monitoring Log <- is a log
Removed: SOP 535 - Animal Facility Regulations
Of interest: Article Body Condition Score for Rats
The storage conditions and physical security for the controlled substance must meet the requirements of the "Directive on Physical Security Requirements for Controlled Substances", available on the Health Canada website.
For scientific exemptions, the required security level is Security Level - 1 and the maximum licensee holdings is $5000. Please note that each researcher must have his or her own storage.
The researcher is required to maintain records with respect to his/her possession and use of the controlled substance in accordance with the applicable regulations. The researcher shall furnish such information respecting such controlled substances as the Minister may requires and shall permit access to the records required to be kept by these Regulations. Specifically, the researcher must keep and retain for a period of two years from the making of such record, the following information:
• the kind, date and quantity of any controlled substance purchased or received;
• the name and address of the person from whom the controlled substance was received; and particulars of the use to which the controlled substance was put.
The researcher is responsible for the destruction of any unused or expired controlled substance. The destruction must be witnessed by a member of his/her research staff who is working on the same research project as specified in the exemption, and who works under the researcher’s direction and control. The method of destruction used must alter or denature the controlled substance in such a way as to make it non-recoverable and thus make their consumption improbable or impossible. The researcher is required to keep and retain for a period of two years from the date of the making of the record, the following information:
• the name, strength per unit, and quantity of any controlled substance to be destroyed;
• the date of destruction; and
• the reason for destruction.
Immediately following the destruction, the researcher and the witness are required to sign and print their names on a joint statement indicating that they witnessed the destruction and that the controlled substance destroyed has been altered or denatured to such an extent that its consumption has been rendered impossible or improbable.
The researcher shall make such records available to the Minister or an inspector upon request.
The Public Health Agency of Canada has implemented since December 2015, new regulations pertaining to the use of Human Pathogens and Toxins. Background information can be found on their website and details on the regulation here.
In order to work with Biohazardous Materials in a laboratory setting, researchers must complete an “Application to Use Biohazardous Materials”. These applications are reviewed and approved by McGill's Environmental Health and Safety Office (not the Animal Care Committee). Approval of the Application means that the researcher is compliant with the Biosafety Programwhich includes lab inspections and training.
Useful links (these two are also available as free Apps for a smart phone or tablet as well):
- Canadian Biosafety Standard (CBS), 2nd edition.
- Public Health Agency of Canada Pathogen Safety Data Sheets (PSDS).
Small Animal Research Unit (SARU)
Large Animal Research Unit (LARU)
Macdonald Campus Farm Cattle Complex
Donald McQueen Shaver Poultry Complex
McGill University Animal Incident Report Form:
Template for a Crisis Management and Communication Plan SOP: