Simon Grandjean Lapierre, MD, M.Sc., FRCPC
Associate Professor in the Microbiology, Infectious Diseases and Immunology Department of Université de Montréal
Clinical-investigator position at the Montreal University Hospital Research Center (CRCHUM)
Visiting researcher at Institut Pasteur de Madagascar
Telephone : 514 890-8000 # 20935
Tuberculosis Care and Research
Simon Grandjean Lapierre completed a MD at Université de Sherbrooke and residency training in Internal Medicine, Infectious Diseases and Medical Microbiology at Université de Montréal. He also completed a MSc in molecular diagnostics applied to mycobacteria at Université Aix-Marseille and then did post-doctoral training in sequencing-based TB diagnostics implementation and novel technologies in Global Health in Madagascar. He is currently an Associate Professor in the Microbiology, Infectious Diseases and Immunology Department of Université de Montréal and holds a clinical-investigator position at the Montreal University Hospital Research Center (CRCHUM).
Simon Grandjean Lapierre directs a translational research program focusing on the impact of molecular epidemiology on TB control in high burden settings and new technologies including digital cough monitoring for screening and clinical monitoring off TB disease. His research is supported by the Fonds de Recherche Santé Québec, Canadian Institutes for Health Research and the Wellcome Trust.
Technologies & public health
LaFleur M, Reuter KE, Hall MB, Rasoanaivo HB, McKernan S, Ranaivomanana P, Michel A, Rabodoarivelo MS, Iqbal Z, Grandjean Lapierre S, Rakotosamimanana N. Drug-resistant tuberculosis in pet ringtailed lemur, Madagascar.Emerg Inf Dis. 27(3): 977-979. (2021) https://doi.org/10.3201/eid2703.202924
Grandjean Lapierre, S., Knoblauch, A.M., Randriamanana, D. et al. Multidrug-resistant tuberculosis surveillance and cascade of care in Madagascar: a five-year (2012–2017) retrospective study. BMC Med 18, 173 (2020). https://doi.org/10.1186/s12916-020-01626-6
Hunt M, Bradley P, Grandjean Lapierre S et al. Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe [version 1; peer review: 2 approved, 1 approved with reservations]. Wellcome Open Res, 4:191 (2019) https://doi.org/10.12688/wellcomeopenres.15603.1
Rakotosamimanana, N., Grandjean Lapierre, S., Raharimanga, V. et al. Performance and impact of GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit® assays on tuberculosis case detection in Madagascar. BMC Infect Dis 19, 542 (2019). https://doi.org/10.1186/s12879-019-4198-6
Bahrainwala L, Knoblauch AM, Andriamiadanarivo A, Diab MM, McKinney J, Small PM, Grandjean Lapierre, S., et al. (2020) Drones and digital adherence monitoring for community-based tuberculosis control in remote Madagascar: A cost-effectiveness analysis. PLoS ONE 15(7): e0235572. https://doi.org/10.1371/journal.pone.0235572
Nouvet E, Knoblauch AM, Passe I, Grandjean Lapierre, S., et al. Perceptions of drones, digital adherence monitoring technologies and educational videos for tuberculosis control in remote Madagascar: a mixed-method study protocol BMJ Open 2019;9:e028073. http://doi.org/10.1136/bmjopen-2018-028073