Madhukar Pai

Prof Madhukar Pai, MD, PhD 
Canada Research Chair in Translational Epidemiology & Global Health
Associate Director, McGill International TB Centre

Dept. of Epidemiology, Biostatistics & Occupational Health
McGill University
1020 Pine Avenue West
Montreal, Canada H3A 1A2

(514) 398-5422 office telephone
(514) 952-6604 cell

madhukar.pai [at]



Madhu Pai did his medical training and community medicine residency in Vellore, India. He completed his PhD in epidemiology at UC Berkeley, and a postdoctoral fellowship at the UCSF.

Madhu serves on the SAGE-IVD committee of WHO, Geneva; Scientific Advisory Committee of FIND, Geneva; and Access Advisory Committee of TB Alliance, New York. He serves as the Chair of the Public-Private Mix (PPM) Working Group of the Stop TB Partnership. He is on the editorial boards of Lancet Infectious Diseases, PLoS Medicine, and BMJ Global Health, among others.

Madhu’s research is mainly focused on improving the diagnosis and treatment of tuberculosis, especially in high-burden countries like India and South Africa. His research is supported by grant funding from the Gates Foundation, Grand Challenges Canada, and Canadian Institutes of Health Research. He has more than 300 publications. He is recipient of the Union Scientific Prize, Chanchlani Global Health Research Award, Haile T. Debas Prize, and David Johnston Faculty & Staff Award. He is a member of the Royal Society of Canada, and a Fellow of the Canadian Academy of Health Sciences.


Infectious diseases epidemiology, tuberculosis, TB diagnosis, TB epidemiology, TB transmission, nosocomial transmission, global health, international health in developing countries

Selected Publications


Pai, Madhukar; Behr, Marcel; Dowdy, David; Dheda, Keertan; Divangahi, Maziar; Boehme, Catharina C; Ginsberg, Ann; Swaminathan, Soumya; Spigelman, Melvin; Getahun, Haileyesus; Menzies, Dick; Raviglione, Mario
Nature Reviews Disease Primers, 2016 (2), pp. 1-23, 2016.

Das, Jishnu; Kwan, Ada; Daniels, Benjamin; Satyanarayana, Srinath; Subbaraman, Ramnath; Bergkvist, Sofi; Das, Ranendra K; Das, Veena; Pai, Madhukar
Use of standardised patients to assess quality of tuberculosis care: a pilot, cross-sectional study
The Lancet Infectious Diseases, 15 (11), pp. 1305–1313, 2015.

Satyanarayana, Srinath; Kwan, Ada; Daniels, Benjamin; Subbaraman, Ramnath; McDowell, Andrew; Bergkvist, Sofi; Das, Ranendra K; Das, Veena; Das, Jishnu; Pai, Madhukar
Use of standardised patients to assess antibiotic dispensing for tuberculosis by pharmacies in urban India: a cross-sectional study
The Lancet Infectious Diseases, 16 (11), pp. 1261–1268, 2016.

Steingart, Karen R; Flores, Laura L; Dendukuri, Nandini; Schiller, Ian; Laal, Suman; Ramsay, Andrew; Hopewell, Philip C; Pai, Madhukar
Commercial serological tests for the diagnosis of active pulmonary and extrapulmonary tuberculosis: an updated systematic review and meta-analysis
PLoS medicine, 8 (8), pp. e1001062, 2011.

Pai, Madhukar; Correa, Natasha; Mistry, Nerges; Jha, Prabhat
Reducing global tuberculosis deaths - time for India to step up
The Lancet, 389 (10075), pp. 1174–1176, 2017.

Pai, Madhukar; Zwerling, Alice; Menzies, Dick
T-cell Based Assays For The Diagnosis Of Latent Tuberculosis Infection: An Update
Annals Intern Med 2008;149:177-184

Small, Peter M; Pai, Madhukar
Tuberculosis diagnosis - time for a game change
N Eng J Med 2010;363:1070-71

Chartrand, Caroline; Leeflang, Mariska MG; Minion, Jessica; Brewer, Timothy; Pai, Madhukar
Accuracy of rapid influenza diagnostic tests: a meta-analysis
Annals of Internal Medicine, 156 (7), pp. 500–511, 2012.

Zwerling, Alice; Behr, Marcel A; Verma, Aman; Brewer, Timothy F; Menzies, Dick; Pai, Madhukar
The BCG World Atlas: a database of global BCG vaccination policies and practices
PLoS Medicine, 8 (3), pp. e1001012, 2011.

Salje, Henrik; Andrews, Jason R; Deo, Sarang; Satyanarayana, Srinath; Sun, Amanda Y; Pai, Madhukar; Dowdy, David W
The importance of implementation strategy in scaling up Xpert MTB/RIF for diagnosis of tuberculosis in the Indian health-care system: a transmission model
PLoS Med, 11 (7), pp. e1001674, 2014.

Denkinger, Claudia; Schito, Marco; Pai, Madhukar (editors).
Tuberculosis diagnostics in 2015: landscape, priorities, needs, and prospects
J Infect Dis 2015;211 (suppl 2)



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