Projects & Partnerships

Tuberculosis Trials Consortium Clinical Research Services (TBTC) 

Click here for project description

Higher Dose Rifampin for 2 Months vs Standard Dose Rifampin for Latent TB

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GeneXpert or chest x-rays or tuberculin testing for household contact assessment – a cluster randomized trial

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Cost-effectiveness of TB screening in Nunavik

Decision tree and supporting materials

Nunavik TB screening manuscript

Nunavik TB screening supplement

Enhancing the public health impact of latent TB infection diagnosis and treatment: A pragmatic cluster randomized trial.

Click here to access the protocol

Click here for training material

Click here for registry analysis tool

Click here for mTST material

Click here for publications

Click here for questionnaires

A randomized clinical trial of 4 months Rifampin vs. 9 months Isoniazid for latent TB infection (Phase 3 effectiveness)

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A randomized trial to compare completion and tolerability of 4 months Rifampin (4 RIF) and 9 months Isoniazid (9 INH) for treatment of latent TB in children

Click here to have more details on the protocol 

Click here to have access to the RCT 4v9 children publication

Click here to have access to the RCT 4v9 adult publication  

Meta-analysis of Individual patient Data (IPD) of Patients with INH (mono or poly-drug) Resistant Tuberculosis. Click here to read the study protocol

Meta-analysis of Individual patient Data (IPD) of Patients with Multi-Drug Resistant Tuberculosis. Click here for resources related to this project.

Partnerships

	PAHO/WHO Collaborating Centers www.paho.org/collaboratingcenters
	Advancing New TB Vaccines for the World www.aeras.org/
	Our vision: A world where diagnosis guides the way to health for all people Our mission: Turning complex diagnostic challenges into simple solutions to overcome diseases of poverty and transform lives www.finddx.org/
	Manipal Centre for Infectious Disease based at Manipal University, Karnataka, India https://manipal.edu/mu.html
	SGC is a public-private partnership that supports the discovery of new medicines through open access research.  www.thesgc.org/
	TB REACH: FINDING AND TREATING PEOPLE WITH TB IN THE WORLD’S POOREST COMMUNITIES www.stoptb.org/global/awards/tbreach/   Partnership involvement
	TB Alliance is a not-for-profit organization dedicated to the discovery and development of better, faster-acting, and affordable tuberculosis drugs that are available to those who need them. www.tballiance.org/