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Frédéric J. Veyrier, Ph.D. tel: 1 (450) 687 5010 # 8831 |
Research
Focus
- Bacterial symbiotes evolution:
- Neisseria meningitidis and other nasopharyngeal pathogens
- Mycobacterium tuberculosis
- Helicobacter pylori
- Bacterial ecology
- Bacteria-bacteria interactions (bactericidal weapons, molecular shields)
- Pathogens cell wall
Keywords
Bacteria, virulence, evolution, bacterial interaction, microbial ecology
Selected Publications
- Williams AH, Veyrier FJ, Bonis M, Michaud Y, Raynal B, Taha MK, Haouz A & Boneca IG*. Visualization of a substrate-induced catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in the SGNH esterase family member. Acta Crystallogr D Biol Crystallogr. 2014 in press
- Radomski N, Roguet A, Lucas FS, Veyrier FJ, Cambau E, Accrombessi H, Moilleron R, Behr MA & Moulin L*. atpE gene as a new useful specific molecular target to quantify Mycobacterium in environmental samples. BMC microbiology, 2013, Dec 3;13:277.
- Veyrier FJ, Ecobichon C, Boneca IG*. Draft Genome Sequence of Helicobacter pylori X47- 2AL. Genome announc, 2013, Dec 19;1(6). pii: e01095-13.
- Veyrier FJ*, Hong E, Deghmane AE, Taha MK*. Draft Genome Sequence of a Neisseria meningitidis Serogroup C Isolate of Sequence Type 11 Linked to an Outbreak among Men Who Have Sex with Men. Genome announc, 2013, Oct 3;1(5). pii: e00795-13.
- Hansen JM, Golchin SA, Veyrier FJ, Domenech P, Boneca IG, Azad AK, Rajaram MVS, Schlesinger LS, Divangahi M, Reed MB & Behr MA*. N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of Mycobacterium tuberculosis. J Infect Dis, 2013, Dec 19. [Epub ahead of print]
- Veyrier FJ*, Williams A, Mesnage S, Schmitt C, Taha MK & Boneca IG*. De-O-acetylation of peptidoglycan regulates glycan chain extension and affects in vivo survival of Neisseria meningitidis. Mol Microbiol, 2013, Mar;87(5):1100-12.
- Hong E, Hedberg ST, Abad R, Fazio C, Enríquez R, Deghmane AE, Jolley KA, Stefanelli P, Unemo M, Vazquez J, Veyrier FJ & Taha MK*. Target gene (gyrA, parC and parE) sequencing to define the susceptibility of Neisseria meningitidis to ciprofloxacin. Antimicrob Agents Chemother, 2013, Apr;57(4):1961-4.
- Veyrier FJ*, Boneca IG, Cellier MF & Taha MK. A novel metal transporter mediating manganese export (MntX) regulates the Mn to Fe intracellular ratio and Neisseria meningitidis virulence. PLOS Pathog, 2011, 7:e1002261
- Veyrier F, Pletzer D, Turenne C & Behr MA*. Phylogenetic detection of horizontal gene transfer during the step-wise genesis of Mycobacterium tuberculosis. BMC Evol Biol, 2009, 9:1961
- Coulombe F, Divangahi M, Veyrier FJ, de Léséleuc L, Gleason J, Yang Y, Kelliher MA, Pandey AK, Sassetti CM, Reed MB & Behr MA*. Increased NOD2-mediated recognition of N-glycolyl muramyl dipetide. J Exp Med, 2009, 206:1709-16
- Divangahi M, Coulombe F, Mostowy S, Kosak R, Veyrier F, Guillot L, Reed MB, Gleason J, Kobayashi KS, Flavell RA, Gros P & Behr MA*. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. J Immunol, 2008, 181:7157-65
- Veyrier F, Said-Salim B & Berh MA*. Evolution of the mycobacterial SigK regulon. J Bacteriol, 2008, 190:1891-9
- Chaloupka R, Courville P, Veyrier F, Knudsen B, Tompkins TA & Cellier MF*. Identification of essential amino acids in the Nramp family by a combination of evolutionary analysis and biophysical studies of metal and proton co-transport in vivo. Biochemistry, 2005, 44:726-33
- Courville P, Chaloupka R, Veyrier F & Cellier MF*. Determination of transmembrane topology of the Escherichia coli natural resistance-associated macrophage protein (Nramp) ortholog. J Biol Chem, 2004, 279:3318-26
Reviews
- Guilhen C, Taha MK & Veyrier FJ*. Role of transition metal exporters in virulence: the example of Neisseria meningitidis. Front Cell Infect Microbiol, 2013, 10.3389/fcimb.2013.00102
- Veyrier FJ, Dufort A & Behr MA*. The rise and fall of the Mycobacterium tuberculosis genome. Trends Microbiol, 2011, 19:156-61
Book chapters
- Wheeler R, Veyrier FJ, Werts C, Boneca IG*. Peptidoglycan and Nod receptors. Glycoscience: Biology and Medicine, Springer
