David Goltzman

David Goltzman

David Goltzman, M.D.

Professor, Departments of Medicine and Physiology
Director, Centre for Advanced Bone and Periodontal research
Director, Calcium Research Laboratory
McGill University Health Centre Glen site, EM1.3220
1001 Decarie Blvd., Montreal, QC H4A 3J1

Tel: 514-843-1632

david.goltzman [at] mcgill.ca

Biographical Sketch

David Goltzman is Professor of Medicine and  Physiology at McGill University and Senior Physician in the Endocrine Division of the Department of Medicine of the McGill University Health Centre. For his research contributions, Dr Goltzman has  received various honours and awards, including the Aurbach Award of the US Endocrine Society, the Raisz Award of the American Society for Bone and Mineral Research (ASBMR), fellowship in the Royal Society of Canada and in the Canadian Academy of Health Sciences, the Order of Canada, an honorary professorship from Nanjing University and the degree of Doctor Honoris Causa from the University of Athens. He is a past President of the ASBMR, the Canadian Society of Clinical Investigation and the Canadian Society of Endocrinology and Metabolism.

Keywords

Hormonal regulation of mineral and skeletal homeostasis.

Research or Clinical Activities

Dr Goltzman`s research has focused on the hormonal regulation of mineral and skeletal homeostasis, and he has made many important contributions to our knowledge of parathyroid hormone (PTH), PTH related peptide and vitamin D, which have had major impact on our understanding of a variety of metabolic bone diseases. He is also principal investigator of the Canadian Multicentre Osteoporosis Study(CaMos) which examines the demographics, development, risk factors and outcomes of osteoporosis.

Selected Recent Publications

Nguyen-Yamamoto L, Karaplis AC, St-Arnaud R, Goltzman D.Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D. J Am Soc Nephrol. 2017 Feb;28(2):586-597.

Bai X, Miao D, Xiao S, Qiu D, St-Arnaud R, Petkovich M, Gupta A, Goltzman D, Karaplis AC CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders. J Clin Invest. 2016 Feb;126(2):667-80.

Camirand A, Goltzman D, Gupta A, Kaouass M, Panda D, Karaplis A. The Role of Parathyroid Hormone-Related Protein (PTHrP) in Osteoblast Response to Microgravity: Mechanistic Implications for Osteoporosis Development. PLoS One. 2016 Jul 27;11(7):e0160034.

Mokry LE, Ross S, Ahmad OS, Forgetta V, Smith GD, Goltzman D, Leong A, Greenwood CM, Thanassoulis G, Richards JB. Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study. PLoS Med. 2016 Mar 2;13(3):e1001981.

Langsetmo L, Barr SI, Berger C, Kreiger N, Rahme E, Adachi JD, Papaioannou A, Kaiser SM, Prior JC, Hanley DA, Kovacs CS, Josse RG, Goltzman D; CaMos Research Group. Associations of Protein Intake and Protein Source with Bone Mineral Density and Fracture Risk: A Population-Based Cohort Study. J Nutr Health Aging. 2015 Oct;19(8):861-8.

PubMed Publications – D. Goltzman