Stéphanie Chevalier

Image of Dr. Stephanie Chevalier

Stéphanie Chevalier, Ph.D.

Associate Professor, School of Human Nutrition

Associate Member of the Department of Medicine, Division of Geriatric Medicine

MUHC-Research Institute

1001, boul. Décarie, E2.7226, Montréal, QC, H4A 3J1

Tel: 514-934-1934 ext. 35019

stephanie.chevalier [at] mcgill.ca

Biographical Sketch

EDUCATION
B.Sc. Nutrition, Registered Dietitian (1986-1989), M.Sc. (1990-1992), Ph.D. Nutrition (1992-1997), Université de Montréal. 
Postdoctoral Fellowship (1998-2004) McGill University, Nutrition & Food Science Centre.

DISTINCTIONS AND AWARDS
FRSQ-Chercheur-boursier Junior 2 (2011-2015) and Junior 1 (2007-2011)
Helen McCall Hutchison Award in Geriatric Medicine (2010)
CDA and FRSQ Postdoctoral Fellowships   

CURRENT PROJECTS 

- Nutritional supplement to improve physical performance in Geriatric Day Hospital participants: a pilot study (MUHC Geriatric Medicine and FRQ-S Réseau Québécois de recherche sur le vieillissement)

- Dairy intakes of older adults of the NuAge longitudinal study: impact on body weight and composition, physical and cognitive function and metabolic profile (Dairy Farmers of Canada)

- Exploring sarcopenia as a predictive factor for the development of cognitive dysfunction (Co-PI: S. Wing)

- Comparison of gut microbial composition in fibromyalgia patients vs. healthy individuals. (Louise and Alan Edwards Foundation, PI: Y. Shir)


MEMBERSHIP
Ordre professionnel des diététistes du Québec (OPDQ), Canadian Nutrition Society (CNS), American Society of Nutrition (ASN), Réseau québécois de recherche sur le vieillissement (RQRV) du FRSQ, Canadian Geriatric Society, Réseau de recherche en santé cardiométabolique, diabète, obésité du FRQS

CONTRIBUTIONS
Leader of Nutrition Axis of the Réseau québécois de recherche sur le vieillissement du FRQS (2013-present), Chair of Canadian Geriatric Society Symposium on Sarcopenia (2015), Organizer of Canadian Nutrition Society Symposium on Nutrition and Aging (2017), Reviewer for numerous grant agencies and scientific journals.  

RESEARCH TRAINEES: 20 in career, 3 current

Keywords

Nutrition, protein metabolism and requirements, aging, sarcopenia, muscle health and function, insulin resistance, cancer cachexia, body composition, hyperinsulinemic clamp, stable isotope tracers. 

Research Activities

My research program has 3 central themes:

The role of dietary protein in age-related muscle and physical function loss: Data analysis from large cohorts of older adults and intervention trials to test protein supplements specifically tailored to improve muscle mass and function of frail older adults, patients with cancer and those undergoing surgery. 

Protein metabolism in aging and metabolic disorders such as cancer cachexia and type 2 diabetes: Studies involve administering glucose and amino acids labelled with stable isotopes for in vivo kinetic measurement under different feeding conditions.

Comprehensive metabolic phenotyping: Measuring body composition, nutritional status, dietary intake, functional capacity and insulin resistance (using the insulin clamp) allows to characterize metabolic and nutritional conditions and test the impact of interventions. 

Selected Recent Publications

Farsijani S, Payette H, Morais JA, Shatenstein B, Gaudreau P and Chevalier S.  Even mealtime distribution of protein intake is associated with greater muscle strength, but not with 3-year decline, in free-living older adults: The NuAge Study.  Am J Clin Nutr 106(1): 113-124, 2017.PMID: 28515070.  Editorial PMID: 28592608

Labonte CC, Farsijani S, Marliss EB, Gougeon R, Morais JA, Pereira S, Bassil M, Winter A, Murphy J, Combs TP and Chevalier S.  Plasma amino acids versus conventional predictors of insulin resistance measured by the hyperinsulinemic clamp.  Journal of the Endocrine Society 1(7): 861-873, 2017. PMID: 29264537

Farsijani S, Morais JA, Payette H, Gaudreau P, Shatenstein B, Gray-Donald K, Chevalier S. Relation between mealtime distribution of protein intake and lean mass loss in free-living older adults of the NuAge study. Am J Clin Nutr 104(3):694-703, 2016.  PMID: 27465379

Chevalier S, Burgos SA, Morais JA, Gougeon R, Bassil M, Lamarche M and Marliss EB.  Protein and glucose metabolic responses to hyperinsulinemia, hyperglycemia and hyperaminoacidemia in obese, glucose tolerant men. Obesity 23 (2): 351-8, 2015. PMID: 25452199

Phillips SM, Chevalier S, Leidy HJ.  Protein “requirements” beyond the RDA: implications for optimizing health.   Appl Physiol Nutr Metab 41(5): 565-72, 2016.  Invited review. PMID: 26960445

PubMed Publications – S. Chevalier