Professor, Ophthalmology and Neurology & Neurosurgery
E-mail: leonard.levin [at] mcgill.ca
Research Areas: Biological Modelling; Cost-effectiveness modeling; Clinical decision analysis
Dr. Levin’s laboratory studies computational approaches to problems in the pathophysiology and clinical aspects of neuro-ophthalmic diseases, using quantitative methods to gain insight into disease processes and health care. Examples include:
(1) Patient-level Markov chain simulation modeling of the progression of diabetic retinopathy in Quebec, in order to evaluate the cost-effectiveness of various screening methodologies;
(2) Simulation of the spread of variance in the drug development process, in order to calculate the powering of translational studies B;
(3) Modeling the diffusion of superoxide anion in the optic nerve of patients with a mitochondrial DNA mutation.