Liquids NMR: Bruker AVIIIHD 800 MHz NMR Spectrometer (“QANUC 800”)

Contact: tara.sprules [at] mcgill.ca (Tara Sprules) - Location: PP023

The QANUC 800 MHz instrument belongs to the Quebec/Eastern Canada High-Field NMR facility and is managed by tara.sprules [at] mcgill.ca (Tara Sprules). The spectrometer is equipped with a 24-place sample changer and a triple resonance cryoprobe, which has excellent sensitivity for ¹H and ¹³C. The probe is optimized for studying biomolecular compounds labelled with ¹³C and/or ¹⁵N, which benefit from the sensitivity and resolution of the high magnetic field. The high sensitivity also allows for rapid acquisition of standard ¹H and ¹³C 1D spectra, as well as 2D homo- and heteronuclear experiments. Data for low concentrations of small molecule can be acquired in several hours, depending on sample characteristics. Samples with high salt concentrations (>200 mM) are only admissible in 3mm NMR tubes (or Bruker shaped tubes). If you require an NMR tube or deuterated solvent these can be provided at cost.

Any academic, government, or industrial group may request time on the QANUC 800 by contacting tara.sprules [at] mcgill.ca (Tara Sprules). Time is allocated on a first-come, first-serve basis. Longer acquisitions, such as 3D protein experiments, may be scheduled over weekends, depending on demand. Users external to McGill can courier samples to the facility or deliver them in person. Training for external users can be provided if necessary.

The QANUC 800 is available to users of the chemistry NMR/EPR facility by contacting Tara or Kirill.  The instrument provides excellent sensitivity and resolution for ¹H and ¹³C 1D experiments and for 2D experiments involving ¹H, ¹³C, or ¹⁵N. Users logged into the McGill VPN can view the QANUC 800 Schedule on the Booked Resource.

If you will require the 800 MHz NMR on a regular basis please contact Tara to discuss training and lab access. For occasional use please fill out the QANUC 800 sample submission form (McGill only). Do not leave any samples in the sample dropoff area until you have been notified that your request can be accommodated.

Assistance with data processing and interpretation is available upon request.