The IHI program is a 75-credit program involving the Departments of Biochemistry, Microbiology and Immunology, and Physiology, and it incorporates elements from each of these disciplines. Since immunology is a key area of biomedical research and is critical to our understanding of the patho-physiology of many immune-mediated diseases, the program provides an excellent foundation for students interested in pursuing a career in biomedical research and/or medicine.
The program consists of 48 required credits in basic science courses, including cell and molecular biology, microbiology and immunology, biochemistry and physiology. There are also 27 Complementary credits which allow for specialization in immunology and related disciplines. To graduate from IHI, students must have a minimum CGPA of 3.30 and must pass five immunology courses (MIMM 214, MIMM 314, PHGY 531, PHGY 419D1 | D2, PHGY 513, and one of BIOC 503, MIMM 509, MIMM 414) with a minimum grade of B.
One of the core components and most rewarding and challenging aspects of the IHI is the Immunology Research Project (PHGY 419D1D2) course. Each student conducts their own independent research project under the supervision of a professor of immunology and participates in all aspects of the project on a collaborative basis with the supervisor and other members of the supervisor’s laboratory. Students gain a first-hand understanding and appreciation of biomedical research by contributing to the design of meaningful experiments, by collecting, analyzing and interpreting the experimental data, and by giving oral presentations and submitting written reports of their work.
If you are considering a supervisor not on the list you must contact the IHI course coordinators for approval.
To be admitted to the IHI program, a student must have a) completed the 6 U1 IHI Required Courses, b) obtained a grade of B or higher in MIMM 214, c) taken at least 27 U1 credits, and d) achieved a CGPA of 3.30 or higher. Students may enter the program from Biochemistry, Microbiology and Immunology, Physiology, and other biomedical departments such as Anatomy and Cell Biology or Pharmacology and Therapeutics. Since enrolment is limited, admission may be denied if demand exceeds the number of available places. If places are available students may also be admitted up to the end of their U2 year.
Prospective applicants to the IHI program must carefully review all eligibility and program requirements before beginning the application process. To apply, students must complete the following steps:
1. Fill out the IHI online application form.
2. Upload a CV as a single PDF file (maximum 3 pages) to the application form.
For those admitted to the IHI program: congratulations! We usually receive around twice the applications that we can accept. We recommend that you start emailing labs (please see most up to date spreadsheet of potential supervisors above) early, by January/February of your U2 year at the latest. Note that if you are considering any labs NOT on the supervisor list, you need to email us BEFORE you agree to work in their lab. We have an onboarding process for new supervisors and want to ensure that all of you are embedded in an exciting environment where you will be well-supported for your IHI project. When emailing perspective supervisors, do tailor your email to your specific research interests and of the research interests of who you are emailing! Attach your latest CV and transcript, and, in your email, outline why you are keen to join their team.
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Course #
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Title
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Credits
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BIOL 200. Molecular Biology.
Credits: 3 Offered by: Biology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression.
- Fall
- 3 hours lecture, 1 hour optional tutorial
- Prerequisite: BIOL 112 or equivalent
- Corequisite: CHEM 212 or equivalent, or CHEM 204
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Molecular Biology |
3 |
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Credits: 3 Offered by: Biology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
This course introduces the student to our modern understanding of cells and how they work. Major topics to be covered include: photosynthesis, energy metabolism and metabolic integration; plasma membrane including secretion, endocytosis and contact mediated interactions between cells; cytoskeleton including cell and organelle movement; the nervous system; hormone signaling; the cell cycle.
- Winter
- 3 hours lecture, 1 hour optional tutorial
- Prerequisite: BIOL 200.
- Restriction: Not open to students who have taken or are taking ANAT 212 or BIOC 212
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BIOC 212. Molecular Mechanisms of Cell Function.
Credits: 3 Offered by: Biochemistry (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.
- Winter
- Prerequisite: BIOL 200
- Restrictions: A non-terminal course intended to be followed by BIOC 311; BIOC 312 in the U2 year. Not open to students who have taken or are taking BIOL 201 or ANAT 212.
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Cell Biology and Metabolism
Molecular Mechanisms of Cell Function
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3
3
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CHEM 212. Introductory Organic Chemistry 1.
Credits: 4 Offered by: Chemistry (Faculty of Science) Terms offered: Summer 2025, Fall 2025
Description
A fundamental study of aliphatic compounds and saturated functional groups including modern concepts of bonding, reaction mechanisms, conformational analysis, spectroscopy, and stereochemistry.
- Fall, Summer
- Prerequisite: CHEM 110 and CHEM 120 or equivalent.
- Restriction: Not open to students registered in Chemistry or Biochemistry. Not open to students who have taken or are taking CHEM 211, CHEM 242, or equivalent.
- Each lab section is limited enrolment
- Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page (https://www.mcgill.ca/transfercredit/prospective/cegep).
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Organic Chemistry 1 |
4 |
CHEM 222. Introductory Organic Chemistry 2.
Credits: 4 Offered by: Chemistry (Faculty of Science) Terms offered: Summer 2025, Winter 2026
Description
Modern spectroscopic techniques for structure determination. The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. Special topics.
- Winter, Summer
- Prerequisite: CHEM 212 or CHEM 242 or equivalent.
- Restriction: Not open to Chemistry or Biochemistry students. Not open to students who have taken or are taking CHEM 234 or CHEM252.
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Organic Chemistry 2 |
4 |
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MIMM 211. Introductory Microbiology.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
A general treatment of microbiology bearing specifically on the biological properties of microorganisms. Emphasis will be on procaryotic cells. Basic principles of microbial genetics are also introduced.
- Fall
- 3 hours of lecture
- Corequisite: BIOL 200
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PHGY 209. Mammalian Physiology 1.
Credits: 3 Offered by: Physiology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.
- Fall
- 3 hours lectures weekly
- Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent.
- Restriction: Not open to students who have taken PHGY 211 or students who are taking and who have taken NSCI 200.
- Restriction: For students in the Faculty of Science, and other students by permission of the instructor
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Introductory Microbiology
Mammalian Physiology 1
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3
3
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MIMM 214. Introductory Immunology: Elements of Immunity.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Basic immunology, organs and cells, elements of innate immunity, phagocytes, complement, elements of adaptive immunity, B-cells, T-cells, antigen presenting cells, MHC genes and molecules, antigen processing and presentation, cytokines and chemokines. Emphasis on anatomy and the molecular and cellular players working together as a physiological system to maintain human health.
- Prerequisite: BIOL 200
- Corequisite: BIOL 201 or ANAT 212/BIOC 212
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Introduction to Immunology |
3 |
ANAT 214. Systemic Human Anatomy.
Credits: 3 Offered by: Anatomy and Cell Biology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Introduction to the gross anatomy of the various organ systems of head, neck and trunk regions of the human body. Emphasis on functional anatomy. Laboratory component includes exploration of the human body through cadaveric prosections, imaging and other materials.
- Fall
- 2 hours lectures, 2 hours laboratory
- Prerequisites: BIOL 112 (or CEGEP equivalent), PHGY 209 and PHGY 210
- This course is limited in size, with guaranteed admission for all students enrolled in the Department of Anatomy and Cell Biology. Students in other programs will be permitted to enroll as space allows.
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Systematic Human Anatomy |
3 |
ANAT 262. Introductory Molecular and Cell Biology.
Credits: 3 Offered by: Anatomy and Cell Biology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
The architectural, functional and temporal continuity of organelles and the cytoskeleton of mammalian cells is introduced as well as their functional integration in the phenomena of exocytosis, endocytosis, protein trafficking and cell motility and adhesion.
- Winter
- 3 hours lecture
- Corequisites: ANAT 212 or BIOC 212 or BIOL 201
- Restriction: Open to students in biological sciences and others by special permission
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Introductory Molecular and Cell Biology |
3 |
BIOL 202. Basic Genetics.
Credits: 3 Offered by: Biology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Introduction to basic principles, and to modern advances, problems and applications in the genetics of higher and lower organisms with examples representative of the biological sciences.
- Winter
- 3 hours lecture, 1 hour optional tutorial per week
- Prerequisite: BIOL 200 or BIOL 219
- Restriction: Not open to students who have taken or are taking LSCI 204 or BIOL 302.
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Basic Genetics |
3 |
BIOL 205. Functional Biology of Plants and Animals.
Credits: 3 Offered by: Biology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Unified view of form and function in animals and plants. Focus on how the laws of chemistry and physics illuminate biological processes relating to the acquisition of energy and materials and their use in movement, growth, development, reproduction and responses to environmental stress.
- Winter
- 3 hours lecture, optional conference hour
- Prerequisites: BIOL 200 or BIOL 219 or permission of the instructor
- Corequisite: ANAT 212/BIOC 212 or BIOL 201
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Biology of Organisms |
3 |
BIOL 304. Evolution.
Credits: 3 Offered by: Biology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
A comprehensive introduction to evolutionary biology. It covers both short-term and long-term evolutionary processes. Topics include the history of life, the origin of species, adaptation, natural selection and sexual selection.
- Fall
- 3 hours lecture.
- Prerequisite: BIOL 205 and BIOL 215 or ENVR 202
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Evolution |
3 |
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CHEM 203. Survey of Physical Chemistry.
Credits: 3 Offered by: Chemistry (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
The fundamentals of thermodynamics and chemical kinetics with applications to biomolecular systems. Thermodynamic and kinetic control of biological processes.
- Fall
- Prerequisites: CHEM 110 and CHEM 120 or equivalent.
- Restrictions: Intended for students in biological science programs requiring only one course in physical chemistry. Not open to students who have taken or are taking CHEM 204 or CHEM 213 or CHEM 223 and CHEM 243.
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CHEM 204. Physical Chemistry/Biological
Sciences 1.
Credits: 3 Offered by: Chemistry (Faculty of Science) Terms offered: Fall 2025, Winter 2026
Description
Similar to CHEM 223/ CHEM 243. Emphasis on the use of biological examples to illustrate the principles of physical chemistry. The relevance of physical chemistry to biology is stressed.
- Fall, Winter
- Prerequisites: CHEM 110 and CHEM 120 or equivalent and one full course in calculus
- Restriction: Not open to students who have taken or are taking CHEM 203 or CHEM 213.
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Survey of Physical Chemistry
Physical Chemistry/Biological Sciences 1
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3
3
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CHEM 287. Introductory Analytical Chemistry.
Credits: 2 Offered by: Chemistry (Faculty of Science)
This course is not offered this catalogue year.
Description
Qualitative and quantitative analysis. A survey of methods of analysis including theory and practice of semimicro qualitative analysis and representative gravimetric, volumetric and instrumental methods.
- Fall
- Prerequisites: CHEM 110 and CHEM 120, or CHEM 115, or equivalent.
- Corequisite: Students in CHEM 287 are required to take the laboratory, CHEM 297, either simultaneously with CHEM 287 or in the term following CHEM 287.
- Restrictions: Not open to students who have taken CHEM 257D1/D2 or CHEM 277D1/D2.
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CHEM 297. Introductory Analytical Chemistry Laboratory.
Credits: 1 Offered by: Chemistry (Faculty of Science)
This course is not offered this catalogue year.
Description
Introductory experiments in analytical chemistry emphasizing classical and instrumental methods of quantitative analysis.
- Fall, Winter
- Prerequisites: CHEM 110 and CHEM 120, or CHEM 115, or equivalent.
- Pre- or Co-requisite: CHEM 287.
- Restriction: Not open to students who have taken CHEM 257D1/D2 or CHEM 277D1/D2.
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Introductory Analytical Chemistry
Introductory Analytical Chemistry Laboratory |
2
2 |
COMP 202. Foundations of Programming.
Credits: 3 Offered by: Computer Science (Faculty of Science) Terms offered: Summer 2025, Fall 2025, Winter 2026
Description
Introduction to computer programming in a high level language: variables, expressions, primitive types, methods, conditionals, loops. Introduction to algorithms, data structures (arrays, strings), modular software design, libraries, file input/output, debugging, exception handling. Selected topics.
- 3 hours
- Restrictions: Not open to students who have taken or are taking COMP 204, COMP 208, or GEOG 333; not open to students who have taken or are taking COMP 206 or COMP 250.
- COMP 202 is intended as a general introductory course, while COMP 204 is intended for students in life sciences, and COMP 208 is intended for students in physical sciences and engineering.
- To take COMP 202, students should have a solid understanding of pre-calculus fundamentals such as polynomial, trigonometric, exponential, and logarithmic functions.
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Foundations of Programming |
3 |
COMP 250. Introduction to Computer Science.
Credits: 3 Offered by: Computer Science (Faculty of Science) Terms offered: Fall 2025, Winter 2026
Description
Mathematical tools (binary numbers, induction,recurrence relations, asymptotic complexity,establishing correctness of programs). Datastructures (arrays, stacks, queues, linked lists,trees, binary trees, binary search trees, heaps,hash tables). Recursive and non-recursivealgorithms (searching and sorting, tree andgraph traversal). Abstract data types. Objectoriented programming in Java (classes andobjects, interfaces, inheritance). Selected topics.
- 3 hours
- Prerequisite(s): MATH 140 or equivalent. COMP 202 or COMP 204 or COMP 208 (or equivalent).
- Corequisite(s): MATH 133
- Restriction(s): Not open to students who have taken or are taking ECSE 250.
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Introduction to Computer Science |
3 |
MATH 204. Principles of Statistics 2.
Credits: 3 Offered by: Mathematics and Statistics (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
The concept of degrees of freedom and the analysis of variability. Planning of experiments. Experimental designs. Polynomial and multiple regressions. Statistical computer packages (no previous computing experience is needed). General statistical procedures requiring few assumptions about the probability model.
- Winter
- Prerequisite: MATH 203 or equivalent. No calculus prerequisites
- Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps.
- You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.
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Principles of Statistics 2 |
3 |
MIMM 211. Introductory Microbiology.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
A general treatment of microbiology bearing specifically on the biological properties of microorganisms. Emphasis will be on procaryotic cells. Basic principles of microbial genetics are also introduced.
- Fall
- 3 hours of lecture
- Corequisite: BIOL 200
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Introductory Microbiology |
3 |
MIMM 212. Laboratory in Microbiology.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
This laboratory course is designed to complement MIMM 211. Sessions introduce general techniques peculiar to the handling of microorganisms.
- Fall
- 3 hours laboratory, 1 hour lecture, 1 hour follow-up
- Corequisite: MIMM 211
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Laboratory in Microbiology |
3 |
PHGY 209. Mammalian Physiology 1.
Credits: 3 Offered by: Physiology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.
- Fall
- 3 hours lectures weekly
- Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent.
- Restriction: Not open to students who have taken PHGY 211 or students who are taking and who have taken NSCI 200.
- Restriction: For students in the Faculty of Science, and other students by permission of the instructor
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Mammalian Physiology 1 |
3 |
PHGY 210. Mammalian Physiology 2.
Credits: 3 Offered by: Physiology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.
- Winter
- 3 hours lectures weekly
- Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisite: BIOL 200, BIOL 201, BIOC 212, CHEM 212 or equivalent.
- Restriction: For students in the Faculty of Science, and other students by permission of the instructor
- Although PHGY 210 may be taken without the prior passing of PHGY 209, students should note that they may have some initial difficulties because of lack of familiarity with some basic concepts introduced in PHGY 209
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Mammalian Physiology 2 |
3 |
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BIOC 220. Laboratory Methods in Biochemistry and Molecular Biology 1.
Credits: 3 Offered by: Biochemistry (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Introduction to key methodologies for the isolation, detection and characterization of proteins, lipids, nucleic acids and subcellular fractions, including spectrophotometry, assays of enzymatic activities and chromatographic and electrophoretic methods. Analysis of biochemical data.
- Prerequisite(s): BIOL 200
- Corequisite(s): BIOC 212 and CHEM222
- Restriction(s): Not open to students who have taken or are taking BIOL 301. Open to students in Biochemistry programs, others with permission of the instructor.
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BIOC 320. Laboratory Methods in Biochemistry and Molecular Biology 2.
Credits: 3 Offered by: Biochemistry (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Modern molecular-biological methods for isolation and characterization of nucleic acids and for analysis of RNA and protein expression, including: plasmid expression, isolation, restriction and ligation; electrophoretic methods and Western blotting; PCR and qPCR applications; immunofluorescence microscopy and basic bioinformatics approaches.
- Prerequisite(s): BIOC 220
- Restriction(s): Not open to students who have taken or are taking BIOL 301. Open to students in Biochemistry programs; others with permission of the instructor.
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MIMM 384. Molecular Microbiology Laboratory.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
A series of laboratory exercises in molecular biology and microbial genetics during the Fall term. As part of a term paper writing project, students will explore contemporary research subjects that represent the wide interests of the Microbiology and Immunology departmentâ•Žs faculty. The general objective is to provide practical and theoretical introduction to the technology and methodology used in contemporary microbiology research.
- Prerequisite(s): MIMM 211 and MIMM 212
- Corequisite(s): MIMM 323 and MIMM 324
- Restriction(s): Not open to students who are taking or have taken MIMM 386D1/D2.
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MIMM 385. Laboratory in Immunology.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
This laboratory course allows students to gain expertise in following protocols and performing key techniques in immunology. Students also develop basic experimental design and scientific thinking skills by designing their own experiments based on available reagents to solve a problem. Students learn to keep a lab book and communicate scientific findings in written and oral form.
- Prerequisite(s): MIMM 211, MIMM 212, MIMM 214 (MIMM 384 highly recommended).
- Corequisite(s): MIMM 314
- Not open to students who are taking or have taken MIMM 386D1/D2.
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PHGY 212. Introductory Physiology Laboratory 1.
Credits: 1 Offered by: Physiology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Exercises illustrating fundamental principles in physiology: Biological Signals Acquisitions, Blood, Immunology, Neurophysiology, Neuromuscular Physiology.
- (One 3-hour lab and one 1-hour lecture every second week.)
- Corequisite: PHGY 209.
- Restrictions: Required for Physiology students enrolled in PHGY 209. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.
- Note: For students in a Physiology program, PHGY 212 should be taken concurrently with PHGY 209.
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PHGY 213. Introductory Physiology Laboratory 2.
Credits: 1 Offered by: Physiology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Exercises illustrating fundamental principles in physiology: Central Nervous System, Cardiovascular, Respiration, Exercise Physiology, Molecular Endocrinology.
- (One 3-hour lab and one 1-hour lecture every second week.)
- Prerequisite: PHGY 212
- Corequisite: PHGY 210.
- Restrictions: Required for Physiology students enrolled in PHGY 210. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.
- Note: For students in a Physiology program, PHGY 213 should be taken concurrently with PHGY 210.
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BIOL 301. Cell and Molecular Laboratory.
Credits: 4 Offered by: Biology (Faculty of Science) Terms offered: Fall 2025, Winter 2026
Description
An introduction to biology research and communication with a focus on cell and
molecular biology. Through conducting a series of project-based experiments and writing a final report, molecular and synthetic biology techniques such as gene cloning, manipulation, protein isolation and characterization and how
research is conducted, analyzed and communicated will be addressed. In addition, an
introduction to bioinformatics methods and their role in analysis will be provided.
- Fall or Winter
- 1 hour lecture and one 6-hour laboratory
- Prerequisites: BIOL 200, BIOL 201 (or ANAT 212/BIOC 212); or BIOL 219
- Restrictions: Not open to students who have taken or are taking BIOC 300, or BIOC 220 and BIOC 320. Requires departmental approval.
- For approval email maxime.leroux [at] mcgill.ca. Specify your ID number as well as the term and two lab day preferences.
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Laboratory Methods in Biochemistry and Molecular Biology 1
Laboratory Methods in Biochemistry and Molecular Biology 2
Molecular Microbiology Lab
Laboratory in Immunology
Introductory Physiology Laboratory 1
Introductory Physiology Laboratory 2
Cell and Molecular Laboratory
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3
3
3
3
1
1
4
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ANAT 365. Cellular Trafficking.
Credits: 3 Offered by: Anatomy and Cell Biology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
This course explores the fundamental mechanisms that govern the organizations of intracellular membranes, how vesicle generation is signaled, how the membranes curve and bud, and how vesicles know where to go and fuse. In addition to intracellular vesicles, the principles of mitochondrial dynamics and process of cellular autophagy are examined. Also, there is a focus on "Applied Cell Biology", with respect to how the exquisite regulation of cellular transport plays a central role in complex biological systems. A series of modules will take students through the mechanisms of cellular polarity, neurotransmission, metabolic cell biology, pathogen invasion, and more. The emphasis is on the morphological aspects of the processes, and on the major techniques that led to discovery.
- Fall
- 3 hours lectures
- Prerequisites: ANAT 261, ANAT 262, PHGY 209, or by permission of instructor
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Cellular Trafficking |
3 |
BIOL 300. Molecular Biology of the Gene.
Credits: 3 Offered by: Biology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction.
- Fall
- 3 hours lecture
- Prerequisites: BIOL 219 or BIOL 200 plus either BIOL 201 or ANAT 212/BIOC 212
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Molecular Biology of the Gene |
3 |
BIOL 314. Molecular Biology of
Cancer.
Credits: 3 Offered by: Biology (Faculty of Science)
This course is not offered this catalogue year.
Description
The molecular basis of human cancers, including analyzing the events that promote the formation of oncogenes and inhibit tumour suppressor genes, the biochemical properties of the proteins encoded by these genes, and their functions.
Current molecular targets for cancer therapy and the concepts and consequences of inheriting mutations in genes that predispose to cancer.
- Fall
- 3 hours lecture
- Prerequisites: BIOL 200, and BIOL 201 or ANAT 212 /BIOC 212; or BIOL 219.
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Molecular Biology of Oncogenes |
3 |
CHEM 302. Introductory Organic Chemistry 3.
Credits: 3 Offered by: Chemistry (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Topics covered may include the following: Aromatic compounds, heterocyclic chemistry, sulfur and phosphorus chemistry, organosulfur and organophosphorus compounds, and biomolecules such as lipids, carbohydrates, amino acids, polypeptides, DNA and RNA.
- Fall
- Prerequisites: CHEM 222, or permission of the instructor.
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Introductory Organic Chemistry 3 |
3 |
MATH 222. Calculus 3.
Credits: 3 Offered by: Mathematics and Statistics (Faculty of Science) Terms offered: Summer 2025, Fall 2025, Winter 2026
Description
Taylor series, Taylor's theorem in one and several variables. Review of vector geometry. Partial differentiation, directional derivative. Extreme of functions of 2 or 3 variables. Parametric curves and arc length. Polar and spherical coordinates. Multiple integrals.
- Prerequisite: MATH 141. Familiarity with vector geometry or Corequisite: MATH 133
- Restriction: Not open to students who have taken or are taking MATH 150, MATH 151, MATH206, or MATH 262.
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Calculus 3 |
3 |
MATH 315. Ordinary Differential Equations.
Credits: 3 Offered by: Mathematics and Statistics (Faculty of Science) Terms offered: Fall 2025, Winter 2026
Description
First order ordinary differential equations including elementary numerical methods. Linear differential equations. Laplace transforms. Series solutions.
- Prerequisite: MATH 222.
- Corequisite: MATH 133.
- Restriction: Not open to students who have taken or are taking MATH 325.
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BIOL 309. Mathematical Models in Biology.
Credits: 3 Offered by: Biology (Faculty of Science)
This course is not offered this catalogue year.
Description
Application of finite difference and differential equations to problems in cell and developmental biology, ecology and physiology. Qualitative, quantitative and graphical techniques are used to analyze mathematical models and to compare theoretical predictions with experimental data.
- Fall
- 3 hours lecture
- Prerequisites:BIOL 200, BIOL 201 (or ANAT 212/BIOC 212); or BIOL 219
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Ordinary Differential Equations
Mathematical Models in Biology |
3
3 |
MIMM 323. Microbial Physiology.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
An introduction to the composition and structure of microbial cells, the biochemical activities associated with cellular metabolism and how these activities are regulated and coordinated. The course will have a molecular and genetic approach to the study of microbial physiology.
- Fall
- 3 hours of lecture
- Prerequisite: MIMM 211
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Microbial Physiology |
3 |
MIMM 324. Fundamental Virology.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
A study of the fundamental properties of viruses and their interactions with host cells. Bacteriophages, DNA- and RNA-containing animal viruses, and retroviruses are covered. Emphasis will be on phenomena occurring at the molecular level and on the regulated control of gene expression in virus-infected cells.
- Fall
- 3 hours of lecture
- Prerequisites: MIMM 211, BIOL 200, BIOL 201 or BIOC 212
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Fundamental Virology |
3 |
PATH 300. Human Disease.
Credits: 3 Offered by: Pathology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Provides a fundamental understanding of the diseases prevalent in North America, for upper level students in the biological sciences. Includes: general responses of cells and organ systems to injury; assessment of individual diseases by relating the causes, symptoms, diagnosis, treatment and prevention to the primary biological abnormalities in each disorder.
- Winter
- Prerequisites: BIOL 200, BIOL 201 or BIOC 212, PHGY 209. Pre-/co-requisite: PHGY 210
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Human Disease |
3 |
PHAR 300. Drug Action.
Credits: 3 Offered by: Pharmacology and Therapeutics (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Principles of pharmacology and toxicology. Frequently encountered drugs will be used as a focus to illustrate sites and mechanisms of action, distribution, metabolism, elimination and adverse side effects.
- Fall
- Prerequisites: BIOL 200, PHGY 209, PHGY 210 and one of BIOL 201 or ANAT/BIOC 212 or permission of instructor.
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Drug Action |
3 |
PHAR 301. Drugs and Disease.
Credits: 3 Offered by: Pharmacology and Therapeutics (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
This course further explores the basic principles of pharmacology as illustrated by drugs used in the treatment of disease. Emphasis is placed on drugs used for diseases prevalent in North America.
- Winter
- Prerequisite: PHAR 300
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Drugs and Disease |
3 |
PHAR 303. Principles of Toxicology.
Credits: 3 Offered by: Pharmacology and Therapeutics (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth.
- Winter
- Prerequisites: BIOL 200, BIOL 201 or BIOC 212, PHGY 209 and PHGY 210
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Principles of Toxicology |
3 |
PHGY 311. Channels, Synapses and Hormones.
Credits: 3 Offered by: Physiology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system.
- Fall
- 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term
- Prerequisite: PHGY 209 or permission of the instructor.
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Channels, Synapses & Hormones |
3 |
PHGY 312. Respiratory, Renal, and Cardiovascular Physiology.
Credits: 3 Offered by: Physiology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level.
- Winter
- 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term
- Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor
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Respiratory, Renal & Cardiovascular Physiology |
3 |
PHGY 313. Blood, Gastrointestinal, and Immune Systems Physiology.
Credits: 3 Offered by: Physiology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology.
- Winter
- 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term
- Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor
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Blood, Gastrointestinal & Immune Systems Physiology |
3 |
PHGY 314. Integrative Neuroscience.
Credits: 3 Offered by: Physiology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours.
- Fall
- 3 hours of lectures per week
- Prerequisites: PHGY 209
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Integrative Neuroscience |
3 |
BIOC 404. Biophysical Methods in Biochemistry.
Credits: 3 Offered by: Biochemistry (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Applications and fundamental bases of important biophysical techniques used in modern biochemistry research laboratories to isolate, characterize and determine the structure and dynamics of proteins, nucleic acids, small molecules and complexes that underlie life and disease.
- Winter
- Prerequisites: CHEM 204, CHEM 214 or equivalent
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Biophysical Chemistry |
3 |
BIOC 450. Protein Structure and Function.
Credits: 3 Offered by: Biochemistry (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Primary, secondary, tertiary and quaternary structure of enzymes. Active site mapping and site-specific mutagenesis of enzymes. Enzyme kinetics and mechanisms of catalysis. Multienzyme complexes.
- Fall
- Prerequisites: BIOC 311, BIOC 312 and/or sufficient organic chemistry.
- Restriction: Intended primarily for students at the U3 level
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Protein Structure and Function |
3 |
BIOC 454. Nucleic Acids.
Credits: 3 Offered by: Biochemistry (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
RNA processing, localization and stability. RNAi mechanisms, regulation and applications. Regulation of DNA replication. Genomics: human genome sequence, regulation and organization. DNA repair mechanisms. Special topics on transgenics, genetic diseases and cancer.
- Fall
- Prerequisites: BIOC 311, BIOC 312 or permission of instructor
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Nucleic Acids |
3 |
BIOC 458. Membranes and Cellular Signaling.
Credits: 3 Offered by: Biochemistry (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
- Winter
- Prerequisites: BIOC 212 or ANAT 212 or BIOL201, ANAT 262, one of PHGY 209 or BIOL 205; one of BIOC 312 or ANAT 365; BIOC 311 recommended
- Restriction: This course is also listed as ANAT 458. Not open to students who have taken or are taking ANAT 458.
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ANAT 458. Membranes and Cellular Signaling.
Credits: 3 Offered by: Anatomy and Cell Biology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
- Winter
- 3 hours lectures
- Prerequisites: BIOC 212 or ANAT 212 or BIOL 201, ANAT 262, one of PHGY 209 or BIOL 205; one of BIOC 312 or ANAT 365; BIOC 311 recommended
- Restriction: This course is also listed as BIOC 458. Not open to students who are taking or who have taken BIOC 458
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Membranes and Cellular Signaling
Membranes and Cellular Signaling |
3
3 |
BIOC 503. Biochemistry of Immune Diseases.
Credits: 3 Offered by: Biochemistry (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Current selected topics in immunology. The biochemical mechanisms underlying various immuno-pathologies and the clinical significance of therapeutic interventions.
- Winter
- Prerequisites: BIOC 311, BIOC 312
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Immunochemistry |
3 |
BIOL 520. Gene Activity in Development.
Credits: 3 Offered by: Biology (Faculty of Science)
This course is not offered this catalogue year.
Description
An analysis of the role and regulation of gene expression in several models of eukaryotic development. The emphasis will be on critical evaluation of recent literature concerned with molecular or genetic approaches to the problems of cellular differentiation and determination. Recent research reports will be discussed in conferences and analyzed in written critiques.
- Winter
- 3 hours lecture and discussion
- Prerequisites: BIOL 300 and BIOL 303 or permission
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Gene Activity in Development |
3 |
EXMD 504. Biology of Cancer.
Credits: 3 Offered by: Medicine (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy.
- Fall
- Prerequisite (Undergraduate): A good knowledge of biology at the cellular and molecular level. Open to U3 and graduate students only
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Biology of Cancer |
3 |
MIMM 413. Parasitology.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
A study of the biology, immunological aspects of host-parasite interactions, pathogenicity, epidemiology and molecular biological aspects of selected parasites of medical importance. Laboratory will consist of a lecture on techniques, demonstrations and practical work.
- Winter
- Prerequisite: MIMM 314 or equivalent - ANAT 261 is strongly recommended
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Parasitology |
3 |
MIMM 465. Bacterial Pathogenesis.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Familiarizes students with key principles and recent advances in our understanding of the strategies that bacteria use to infect and cause disease, as well as the approaches used in the prevention and treatment of bacterial infections.
- Fall
- 3 hours of lecture
- Prerequisites: MIMM 214, MIMM 323, MIMM 384.
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Bacterial Pathogenesis |
3 |
MIMM 466. Viral Pathogenesis.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
A study of the biological and molecular aspects of viral pathogenesis with emphasis on the human pathogenic viruses including the retroviruses HIV and HTLV-1; herpes viruses; papilloma viruses; hepatitis viruses; and new emerging human viral diseases. These viruses will be discussed in terms of virus multiplication, gene expression virus-induced cytopathic effects and host immune response to infection.
- Winter
- 3 hours of lecture
- Prerequisites: MIMM 211, MIMM 324, MIMM 314
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Viral Pathogenesis |
3 |
MIMM 509. Inflammatory Processes.
Credits: 3 Offered by: Microbiology & Immunology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
This course concentrates on the non-specific aspects of the immune response, an area which is not adequately covered by the other immunology courses presented at the university. Interactions between guest researchers (from McGill and other universities) and students will be furthered.
- Winter
- 3 hours of seminar
- Corequisite: PHGY 513 or MIMM 414
- This course will be given in conjunction with the Division of Experimental Medicine
- Prerequisite: MIMM 314
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Inflammatory Processes |
3 |
PHAR 503. Drug Discovery and Development 1.
Credits: 3 Offered by: Pharmacology and Therapeutics (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
Chemistry, mechanisms of action, and steps in drug discovery and development.
- Fall
- Prerequisites: PHAR 301 or PHAR 303; or permission of instructor
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Drug Design and Development 1 |
3 |
PHAR 504. Drug Discovery and Development 2.
Credits: 3 Offered by: Pharmacology and Therapeutics (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Nobel Prize-winning discoveries as a basis for drug development.
- Winter
- Prerequisites: PHAR 301 or PHAR 303; or permission of instructor
- Restriction: U3 and graduate students. Students can register only with permission of coordinators.
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Drug Design and Development 2 |
3 |
PHGY 488. Stem Cell Biology.
Credits: 3 Offered by: Physiology (Faculty of Science) Terms offered: Fall 2025 View offerings for Fall 2025 in Visual Schedule Builder.
Description
The main concepts in stem cell biology: embryonic stem cells, induced pluripotent stem cells, cancer stem cells, stem cells populations of many adult tissues, applications of stem cell biology and ethical issues surrounding stem cell use in research and medicine. The major experimental methods and laboratory techniques in stem cell biology.
- Prerequisite(s): PHGY 313 or by permission of instructor.
- Restriction(s): Registration is on a first-come, first-served basis.
- Restriction(s): Not open to students who are taking or have taken ANAT 416.
- Critical reading of peer-reviewed journal papers, practice in oral presentations of scientific material and participation in group discussions.
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Stem Cell Biology |
3 |
PHGY 552. Cellular and Molecular Physiology.
Credits: 3 Offered by: Physiology (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Discussions of recent significant advances in our understanding of the gene products involved in diverse cellular signalling pathways. Topics will include cell-surface hormone receptors, nuclear steroid hormone receptors, and ion channels and transporters. Students will present and critically evaluate experimental approaches, results and interpretations of selected research publications.
- Winter
- 1 hour lecture, 2 hours seminar weekly
- Prerequisite: PHGY 311
- Preference will be given to Physiology Honours and Graduate students
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Cellular and Molecular Physiology |
3 |
2025-2026 IHI Research Supervisors