Professor
B.Sc. Chemistry (Université du Québec à Chicoutimi)
Ph.D. Organic Chemistry (University of Alberta, Prof. John C. Vederas)
PDF Pharmaceutical Chemistry (University of California, San Francisco, Prof. Paul R. Ortiz de Montellano)
Assistant Professor of Chemistry, McGill University 2002-2008
Associate Professor of Chemistry, McGill University since 2009
Full Professor of Chemistry, McGill University, since 2016
Tier 1 Canada Research Chair in Antimicrobials and Green Enzymes, since 2019
Office: Otto Maass 422
Phone: (514)398-2822
Email: Karine.Auclair [at] McGill.CA
Lab: Otto Maass 200
Lab Phone: (514)398-6229
Web Page: Auclair Group Website
Research Themes
- Chemical Biology
- Synthesis/Catalysis
Research Description
Our research takes advantage of chemical tools to study and manipulate biological systems. We are especially interested in antibiotic resistance and green chemistry. For example we look for new molecules to treat infections, we study allostery in P450 enzymes, develop biocatalytic methods using new strategies such as bioconjugation or mechanoenzymology in the absence of bulk water.
Currently Teaching
CHEM 332. Biological Chemistry.
Credits: 3
Offered by: Chemistry (Faculty of Science)
This course is not offered this catalogue year.
Description
An introduction to biological chemistry. Topics will include chemistry and structure of proteins, nucleic acids, and lipids; protein and nucleic acid biosynthesis; enzyme kinetics and mechanisms; membranes and membrane transport; bioenergetics; redox reactions in biological chemistry; gene expression; cloning, RNA and
antibody technologies; genomics and proteomics.
- Prerequisite(s): CHEM 222 and CHEM 273.
- Corequisite(s): CHEM 302
- Restriction(s): Restricted to Chemistry Majors/Honours only except by permission of instructor.
- Restriction(s): Not open to students who are taking or have taken BIOL 200 or BIOL 201.
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CHEM 502. Advanced Bio-Organic Chemistry.
Credits: 3
Offered by: Chemistry (Faculty of Science)
This course is not offered this catalogue year.
Description
This course will cover biologically relevant molecules, particularly nucleic acids, proteins, and their building blocks. In each case, synthesis and biological functions will be discussed. The topics include synthesis of oligonucleotides and peptides; chemistry of phosphates; enzyme structure and function; coenzymes, and enzyme catalysis; polyketides; antiviral and anticancer agents.
- Restriction: Not open to students who have taken CHEM 402.
- Winter
- Prerequisite: CHEM 302
- Restriction: Not open to students who have taken CHEM 402.
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