PHGY 425. Analyzing Physiological Systems.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
An introduction to quantitative analysis of physiological data, both to the mode of thinking and to a set of tools that allows accurate predictions of biological systems. Examples will range from oscillating genetic networks to understanding higher brain function. Modelling and data analysis through examples and exercises will be emphasized.
- Prerequisite: PHGY 311, PHGY 314, BIOL 200 or permission from instructor.
- Note: Enrolment limited to 20 students.
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PHGY 451. Advanced Neurophysiology.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Topics of current interest in neurophysiology including the development of neurons and synapses, physiology of ionic channels, presynaptic and postsynaptic events in synaptic transmission and neuronal interactions in CNS function.
- Fall
- 3 hours lecture
- Prerequisite: PHGY 311 or equivalent
- Restriction: Departmental approval required
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PHGY 488. Stem Cell Biology.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
The main concepts in stem cell biology: embryonic stem cells, induced pluripotent stem cells, cancer stem cells, stem cells populations of many adult tissues, applications of stem cell biology and ethical issues surrounding stem cell use in research and medicine. The major experimental methods and laboratory techniques in stem cell biology.
- Prerequisite(s): PHGY 313 or by permission of instructor.
- Restriction(s): Registration is on a first-come, first-served basis.
- Restriction(s): Not open to students who are taking or have taken ANAT 416.
- Critical reading of peer-reviewed journal papers, practice in oral presentations of scientific material and participation in group discussions.
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PHGY 502. Exercise Physiology.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Behaviour of physiological processes in response to physical effort, in areas such as structural basis of muscle contraction, thermoregulation during exercise, mechanics and energetics of muscle contraction, fuel utilization, fatigue, physiological adjustments during exercise and influence of training.
- Winter
- Prerequisites: PHGY 311, PHGY 312, and PHGY 313
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PHGY 461D1. Experimental Physiology.
Credits: 4.5 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Individual project work under the supervision of Departmental Staff members.
- No credit will be given for this course unless both PHGY 461D1 and PHGY 461D2 are successfully completed in consecutive terms
- No credit will be given for this course unless both PHGY 461D1 and PHGY 461D2 are successfully completed in consecutive terms
- Fall
- Restrictions: Departmental approval required. This course is a requirement for U3 students in the Honours Physiology program, the Major Program in Physiology and Mathematics, and the Major program in Physiology and Physics, and is open to a limited number of other U3 Physiology students.
- Students must register for both PHGY 461D1 and PHGY 461D2.
- No credit will be given for this course unless both PHGY 461D1 and PHGY 461D2 are successfully completed in consecutive terms
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PHGY 461D2. Experimental Physiology.
Credits: 4.5 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
- Winter
- Prerequisite: PHGY 461D1
- No credit will be given for this course unless both PHGY 461D1 and PHGY 461D2 are successfully completed in consecutive terms
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| *the 9 credit course (PHGY 461D1 & PHGY 461D2) equals 3 credits of ULP and 6 credits of electives |
PHGY 508. Advanced Renal Physiology.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Advanced concepts in selected areas of kidney physiology, including the glomerulus, renal cell biology, kidney development, membrane and epithelial transport, hormones and autacoids, kidney transplantation, bioengineering and regenerative medicine.
- Fall. Offered in conjunction with the Department of Medicine.
- Prerequisite (Undergraduate): PHGY 312 or the equivalent
- Restriction: Open to advanced undergraduate and graduate students
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PHGY 513. Translational Immunology.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Advanced key concepts in immunology as they relate to health and disease, including infectious diseases, non-infectious diseases and autoimmunity, and cancer immunology.
- Winter
- 3 hours lectures
- Prerequisite: MIMM 314 or PHGY 313 or permission of the instructor
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PHGY 515. Blood-Brain Barrier in Health and Disease.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Molecular and cellular mechanisms underlying the organization and regulation of the blood-brain barrier, highlighting neurological diseases associated with the blood-brain barrier breakdown and give an overview of experimental approaches to study blood-brain barrier.
- Fall
- 1.5 hours Lecture and 1.5 hours Seminar weekly
- Prerequisite: PHGY 313 or PHGY 314 and permission of the instructor
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PHGY 516. Physiology of Blood
.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Bone marrow hematopoiesis, with emphasis on regulation of stem cell proliferation and differentiation along hematopoietic pathways. Formation and differentiation of red and white blood cells and some of the diseases associated with hematopoiesis will be covered. Emphasis will be given to the molecular mechanisms involved in the normal and pathological conditions.
- Winter
- 2 hours lecture plus 1 hour seminar weekly
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PHGY 518. Artificial Cells.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Physiology, biotechnology, chemistry and biomedical application of artificial cells, blood substitutes, immobilized enzymes, microorganisms and cells, hemoperfusion, artificial kidneys, and drug delivery systems. PHGY 517 and PHGY 518 when taken together, will give a complete picture of this field. However, the student can select one of these.
- Fall
- Prerequisite (Undergraduate): permission of instructors.
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PHGY 520. Ion Channels.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
A discussion of the principal theories and interesting new developments in the study of ion channels. Based on a textbook, computer exercises and critical reading and presentation of research papers. Topics include: Properties of voltage-and ligand-gated channels, single channel analysis, structure and function of ion channels.
- Winter
- Offered in even numbered years
- 1 1/2 hour lecture, 1 1/2 hour seminar
- Prerequisite: PHGY 311
- Priority to Graduate and Honours students; others by permission of instructors.
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PHGY 524. Chronobiology.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
An introduction to the field of chronobiology. The aim is to provide basic instruction on different
types of biological rhythms, with particular focus on circadian rhythms.
- Prerequisites: PHGY 209 and PHGY 210 (or NSCI 200 and NSCI 201), and a relevant 300-level course (PHGY 311, or PHGY 314, or PSYC 318, or BIOC 311, or other, with permission of course coordinator).
- Restriction: Course for senior undergraduate (U3) and graduate students
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PHGY 531. Topics in Applied Immunology.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Seminar format course in which experts in immunologic mechanisms of resistance against a variety of infectious diseases, including AIDS, malaria, and tuberculosis oversee student moderators in their presentation of recent scientific literature in the field.
- Winter
- Restriction: Permission of the instructor. U3 InterDept. Honours Immunology students and graduate students with strong immunology background i.e. PHGY 513 and BIOC 503
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PHGY 550. Molecular Physiology of Bone.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Students will develop a working knowledge of cartilage and bone. Discussion topics will include: molecular and cellular environment of bone; heritable and acquired skeletal defects; research models used to study metabolic bone disease.
- Fall
- 1 hour of lecture, 2 hours of seminar per week
- Prerequisites: PHGY 311, and BIOL 202 or equivalent
- Restriction: U3 Physiology students, and graduate students in biomedical departments; others by permission of the instructor
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PHGY 552. Cellular and Molecular Physiology.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Discussions of recent significant advances in our understanding of the gene products involved in diverse cellular signalling pathways. Topics will include cell-surface hormone receptors, nuclear steroid hormone receptors, and ion channels and transporters. Students will present and critically evaluate experimental approaches, results and interpretations of selected research publications.
- Winter
- 1 hour lecture, 2 hours seminar weekly
- Prerequisite: PHGY 311
- Preference will be given to Physiology Honours and Graduate students
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PHGY 556. Topics in Systems Neuroscience.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Topics of current interest in systems neurophysiology and behavioural neuroscience including: the neural representation of sensory information and motor behaviours, models of sensory motor integration, and the computational analysis of problems in motor control and perception. Students will be expected to present and critically discuss journal articles in class.
- Winter
- Restriction: Permission of the instructor required.
- Restriction: Not open to students who have taken PHGY 456
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PHGY 560. Light Microscopy-Life Science.
Credits: 3 Offered by: Physiology (Faculty of Science)
This course is not offered this catalogue year.
Description
Introduction to optics, light microscopy imaging and data analysis for life scientists.
- Winter
- Prerequisites: BIOL 301 or permission of instructors.
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EXMD 502. Advanced Endocrinology 1.
Credits: 3 Offered by: Medicine (Faculty of Science)
This course is not offered this catalogue year.
Description
This course is designed for U3 students who are in a major or honours program in anatomy, biology, biochemistry or physiology and for graduate students. A multidisciplinary approach will be used to teach biosynthesis and processing of hormones, their regulation, function and mechanism of action. The material will cover hypothalamic, pituitary, thyroid, atrial and adrenal hormones as well as prostaglandins and related substances.
- Prerequisite (Undergraduate): EXMD 301 or an equivalent course
- Fall
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EXMD 503. Advanced Endocrinology 02.
Credits: 3 Offered by: Medicine (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Study of the parathyroids, gut and pancreatic hormones and growth factors. In addition, the role of hormones and growth factors in reproduction and fetal maturation will be discussed.
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EXMD 506. Advanced Applied Cardiovascular Physiology.
Credits: 3 Offered by: Medicine (Faculty of Science)
This course is not offered this catalogue year.
Description
Offered in conjunction with the Department of Physiology. Current topics, methods and techniques for studying the cardiovascular system. Basic and applied cardiac electrophysiology, mechanisms of pacemaker activity, arrhythmias, the effects of drugs on cardiac functions, fetal circulation, coronary circulation, mechanics of blood flow, cardiovascular diseases, renal and neural control of the circulation, and cardiac assist devices.
- Fall
- Prerequisite: PHGY312 or PHGY 313 or permission of the instructors
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EXMD 507. Advanced Applied Respiratory Physiology.
Credits: 3 Offered by: Medicine (Faculty of Science)
This course is not offered this catalogue year.
Description
Offered in conjunction with the Department of Physiology. In depth coverage of respiratory biology including: functional anatomy of the respiratory system, pulmonary statics and dynamics, chest wall and respiratory muscles, ventilation and perfusion, control of breathing, and defense mechanisms. This course is aimed at providing a solid grounding in pulmonary biology and its research applications.
- Fall
- Prerequisite: PHGY 313
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EXMD 508. Advanced Topics in Respiration.
Credits: 3 Offered by: Medicine (Faculty of Science) Terms offered: Winter 2026 View offerings for Winter 2026 in Visual Schedule Builder.
Description
Offered in conjunction with the Department of Physiology. In depth coverage of developmental physiology, pulmonary vascular physiology, biology of airway smooth muscle, respiratory epithelium and molecular biology of respiratory muscles. Dyspnea, mechanical ventilation and respiratory failure will also be covered. This course emphasizes application of respiratory biology to basic and applied research and touches on pulmonary pathophysiology.
- Winter
- Prerequisite: EXMD 507
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