Prime Minister Keir Starmer appears to have been kept in the dark repeatedly over Peter Mandelson, the Jeffrey Epstein associate — fueling an image of weakness.

An anonymous reader quotes a report from Ars Technica: On Thursday, OpenAI announced it had developed a large language model specifically trained on common biology workflows. Called GPT-Rosalind after Rosalind Franklin, the model appears to differ from most science-focused models from major tech companies, which have generally taken a more generic approach that works for various fields. In a press briefing, Yunyun Wang, OpenAI's Life Sciences Product Lead, said the system was designed to tackle two major roadblocks faced by current biology researchers. One is the massive datasets created by decades of genome sequencing and protein biochemistry, which can be too much for any one researcher to take in. The second is that biology has many highly specialized subfields, each with its own techniques and jargon. So, for example, a geneticist who finds themselves working on a gene that's active in brain cells might struggle to understand the immense neurobiological literature. Wang said the company had taken an LLM and trained it on 50 of the most common biological workflows, as well as on how to access the major public databases of biological information. Further training has resulted in a system that can suggest likely biological pathways and prioritize potential drug targets. "We're connecting genotype to phenotype through known pathways and regulatory mechanisms, infer likely structural or functional properties of proteins, and really leveraging this mechanistic understanding," Wang said. To address LLMs' tendencies toward sycophancy and overenthusiasm, OpenAI says it has tuned the model to be more skeptical, so it's more likely to tell you when something is a bad drug target. There was a lot of talk about GPT-Rosalind's "reasoning" and "expert-level" abilities. We were told that the former was defined as being able to work through complex, multi-step processes, while the latter was derived from the model's performance on a handful of benchmarks. Access to GPT-Rosalind is currently limited "due to concerns about the model's potential for harmful outputs if asked to do something like optimize a virus's infectivity," notes Ars. Only U.S.-based organizations can request access at the moment.

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Longtime Slashdot reader AmiMoJo writes: Windows has limited FAT32 partitions to a maximum of 32GB for decades now. When memory cards and USB drives exceeded 32GB in size, the only options were exFAT or NTFS. Neither option was well supported on other platforms at first, although exFAT support is fairly widespread now. In their latest blog post, Microsoft announced that the limit for FAT32 partitions is being increased to 2TB. Of course, that doesn't mean that every device that supports FAT32 will work flawlessly with a 2TB partition size, but at least there is a decent chance that older devices with don't support exFAT will now be usable with memory cards over 32GB.

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The tax expert Ray Madoff explains why the American tax system is broken, and how to make it fairer.

Newly unsealed records in California's antitrust case against Amazon allegedly show the company pressured third-party sellers to raise prices on rival sites like Walmart, Target, and Wayfair so Amazon could maintain the appearance of offering the lowest price. California says Amazon used tools like Buy Box suppression to punish cheaper listings elsewhere. The Guardian reports: [...] In one previously redacted deposition, marked "highly confidential," Mayer Handler, owner of a clothing company called Leveret, testified that he received an email in October 2022 from Amazon notifying him that one of his products was "no longer eligible to be a featured offer" through Amazon's Buy Box. The tech giant, he testified, had suppressed the item, a tiger-themed, toddler's pajama set, because his company was selling it for $19.99 on Amazon, a single cent higher than what his company was offering it for on Walmart. Afterwards, Handler testified, his company "changed pricing on Walmart to match or exceed Amazon's price" or changed the item's product code to try to throw off Amazon's price tracking system. In response to a question from the Guardian, Handler criticized Amazon for tracking prices across the internet and "shadow" blocking his company's products -- tactics which he said were depriving consumers of "lower prices." "Maybe that's capitalism," he wrote. "Or that's a monopoly causing price hikes on the consumer." In another unsealed deposition, Terry Esbenshade, a Pennsylvania garden store supplier, testified in October 2024 that whenever his products lost Amazon's Buy Box because of lower prices elsewhere on the internet, his sales on Amazon would plummet by about 80%. This financial reality forced him to try to raise his products' prices with other retailers elsewhere, he said. In one instance, Esbenshade testified, he discovered that one of his company's better-selling patio tables had "become suppressed" on Amazon. Esbenshade wasn't sure why, he recalled, until someone at Amazon suggested he look at Wayfair, another online retailer that happened to be selling his patio table below Amazon's price. The businessman went online and set up a new minimum advertised price for the table on Wayfair to ensure it was higher than Amazon's. "So that raised the price up, and, voila, my product came back" on Amazon, he said, thanks to the reinstatement of the Buy Box.

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Producers and the cultural authorities hope that technology can overcome a language barrier and take the country’s shows to the world.

An anonymous reader quotes a report from the Wall Street Journal: An agreement with the Philippines to establish a high-tech industrial hub is the Trump administration's latest effort to lessen China's dominance over global supply chains. The deal to build up American manufacturing across a stretch of the island of Luzon, signed Thursday, will offer U.S. companies access to essential inputs such as critical minerals that bypass Beijing's control. The artificial-intelligence-powered manufacturing hub is planned for a 4,000-acre site given to the U.S. by Manila, said undersecretary of State for Economic Affairs Jacob Helberg. The U.S. will occupy the site rent-free and administer it as a special economic zone. The hub will have diplomatic immunity, such as the protections afforded to an American embassy, and operate under U.S. common law -- the first arrangement of its kind anywhere in the world. The two-year lease is renewable for 99 years. [...] "You can't build anything in Ohio if the minerals and the process materials are controlled by an adversary who can cut you off tomorrow," Helberg said in an interview. [...] The planned manufacturing hub is largely conceptual at this stage, and details, including which American companies will participate and just what they will build in the Philippines, are yet to be determined. [...] The administration will ask companies to put forward proposals to compete for a spot in building out the hub, giving priority to bids that will help move critical minerals processing and manufacturing off Chinese suppliers. Investment will have to come from private-sector companies -- not the U.S. government. Factories approved for operation in the hub will be highly automated, Helberg said, using autonomous systems to operate around the clock. The Philippines has a history of robust manufacturing, particularly in semiconductors, but that has stagnated in recent decades because of high energy and logistics costs. Companies will have to address in their proposals how they will contend with energy costs and workforce needs; they can send American workers overseas or hire locally, Helberg said.

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Reed Hastings is stepping down from Netflix's board in June, ending a 29-year run at the company he co-founded and helped transform from a DVD-by-mail business into a global streaming giant. Hastings said in a shareholder (PDF) letter that he's stepping down to focus on "his philanthropy and other pursuits." Engadget reports: Hastings has served as chairman of Netflix's board since 2023, a role he assumed after stepping down as co-CEO and promoting Greg Peters in his place. "Netflix changed my life in so many ways, and my all-time favorite memory was January 2016, when we enabled nearly the entire planet to enjoy our service," Hastings said in a statement. "My real contribution at Netflix wasn't a single decision; it was a focus on member joy, building a culture that others could inherit and improve, and building a company that could be both beloved by members and wildly successful for generations to come. A special thanks to Greg and Ted, whose commitment to Netflix's greatness is so strong that I can now focus on new things."

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Intel has launched a new budget-focused Core Series 3 processor line for lower-cost laptops -- "Intel's response to budget CPUs that are appearing in laptops like the Apple MacBook Neo," writes PCWorld's Mark Hachman. From the report: Intel unexpectedly launched the Core Series 3, based on its excellent "Panther Lake" (Core Ultra Series 3) architecture and 18A manufacturing, for devices for home consumers and small business on Thursday. Intel announced that a number of partners will launch laptops based upon the chip, including Acer, Asus, HP, Lenovo, and others. Although those laptops will be available beginning today, a number of them will begin shipping later this year, the partners said. All of it -- from the specifications down to the messaging -- feels extremely aimed at trimming the fat and delivering to users just what they'll want. Intel's new Core Series 3 family just includes two "Cougar Cove" performance cores and four low-power efficiency "Darkmont" cores, with two Xe graphics cores on top of it. Intel isn't really worrying about AI, with an NPU capable of just 17 TOPS, though the company claims the CPU, NPU, and GPU combined reach 40 TOPS of performance. Yes, laptops will use pricey DDR5 memory, but at the lower end: just DDR5-6400 speeds. Support for three external displays will be included, though, maximizing multiple screens for maximum productivity. Intel used the term "all day battery life" without elaboration. [...] Intel Core Series 3 delivers up to 47 percent better single-thread performance, up to 41 percent better multi thread performance, and up to 2.8x better GPU AI performance, Intel said. Compared against Intel's older Core 7 150U, Intel is saying that the new chip will outperform it by 2.1 times in content-creation and 2.7 times the AI performance. [...] We still don't know what Intel will charge for the chip, nor do we know what you'll be able to buy a Core Series 3 laptop for.

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Ms. Mejia, who helped run Sen. Bernie Sanders’s presidential campaign, beat her Republican opponent, Joe Hathaway, to win a seat Ms. Sherrill vacated after she was elected governor of New Jersey.

An anonymous reader quotes a report from the Guardian: We may appear to have little in common with sperm whales – enormous, ocean-dwelling animals that last shared a common ancestor with humans more than 90 million years ago. But the whales' vocalized communications are remarkably similar to our own, researchers have discovered. Not only do sperm whale have a form of "alphabet" and form vowels within their vocalizations but the structure of these vowels behaves in the same way as human speech, the new study has found. Sperm whales communicate in a series of short clicks called codas. Analysis of these clicks shows that the whales can differentiate vowels through the short or elongated clicks or through rising or falling tones, using patterns similar to languages such as Mandarin, Latin and Slovenian. The structure of the whales' communication has "close parallels in the phonetics and phonology of human languages, suggesting independent evolution," the paper, published in the Proceedings B journal, states. Sperm whale coda vocalizations are "highly complex and represent one of the closest parallels to human phonology of any analyzed animal communication system," it added. [...] The new study shows that "sperm whale communication isn't just about patterns of clicks -- it involves multiple interacting layers of structure," said Mauricio Cantor, a behavioral ecologist at the Marine Mammal Institute who was not involved in the research. "With this study, we're starting to see that these signals are organized in ways we didn't fully appreciate before." The latest discovery around sperm whale speech has inched forward the possibility of someday fully understanding the creatures and even communicating with them. Project CETI has set a goal of being able to comprehend 20 different vocalized expressions, relating to actions such as diving and sleeping, within the next five years. A future where we're able to fully understand what the whales are saying and be able to have a conversation with them is "totally within our grasp," said David Gruber, founder and president of Project CETI. "We've already got a lot further than I thought we could. But it will take time, and funding. At the moment we are like a two-year-old, just saying a few words. In a few years' time, maybe we will be more like a five-year-old."

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The singer was detained in connection with the death of Celeste Rivas Hernandez, who died before her 15th birthday. D4vd’s lawyers said they would vigorously defend his innocence.

The musician is known for creating the anthem for Fortnite. He was touring for his major-label debut when Ms. Rivas Hernandez’s remains were found in his car, officials said.

In an interview with the local news outfit Hell Gate, the New York mayor framed his decision to avoid the glamorous fund-raiser as a way to keep his focus on affordability.

Todd Lyons said he would leave to spend more time with his family. He has spoken about a surge in threats against ICE officers, saying that he knew the reality firsthand.

The suspect is accused of carrying out a string of attacks in the Atlanta area that killed two women and injured a homeless man. The authorities described the attacks as random.

Workers in Cheboygan hurried to shore up a dam in danger of being overtopped, part of a “slow-moving disaster” threatening communities across the state.

An officer from the Police Department’s Mounted Unit raced through the Upper West Side of Manhattan, chasing a woman accused of snatching a purse.

Robert F. Kennedy Jr., who has sought to roll back longstanding vaccine policy, testified that the measles vaccine is safe and effective “for most people” and agreed it was safer than getting measles.

An anonymous reader quotes a report from Ars Technica: Two years ago, Microsoft launched its first wave of "Copilot+" Windows PCs with a handful of exclusive features that could take advantage of the neural processing unit (NPU) hardware being built into newer laptop processors. These NPUs could enable AI and machine learning features that could run locally rather than in someone's cloud, theoretically enhancing security and privacy. One of the first Copilot+ features was Recall, a feature that promised to track all your PC usage via screenshot to help you remember your past activity. But as originally implemented, Recall was neither private nor secure; the feature stored its screenshots plus a giant database of all user activity in totally unencrypted files on the user's disk, making it trivial for anyone with remote or local access to grab days, weeks, or even months of sensitive data, depending on the age of the user's Recall database. After journalists and security researchers discovered and detailed these flaws, Microsoft delayed the Recall rollout by almost a year and substantially overhauled its security. All locally stored data would now be encrypted and viewable only with Windows Hello authentication; the feature now did a better job detecting and excluding sensitive information, including financial information, from its database; and Recall would be turned off by default, rather than enabled on every PC that supported it. The reconstituted Recall was a big improvement, but having a feature that records the vast majority of your PC usage is still a security and privacy risk. Security researcher Alexander Hagenah was the author of the original "TotalRecall" tool that made it trivially simple to grab the Recall information on any Windows PC, and an updated "TotalRecall Reloaded" version exposes what Hagenah believes are additional vulnerabilities. The problem, as detailed by Hagenah on the TotalRecall GitHub page, isn't with the security around the Recall database, which he calls "rock solid." The problem is that, once the user has authenticated, the system passes Recall data to another system process called AIXHost.exe, and that process doesn't benefit from the same security protections as the rest of Recall. "The vault is solid," Hagenah writes. "The delivery truck is not." The TotalRecall Reloaded tool uses an executable file to inject a DLL file into AIXHost.exe, something that can be done without administrator privileges. It then waits in the background for the user to open Recall and authenticate using Windows Hello. Once this is done, the tool can intercept screenshots, OCR'd text, and other metadata that Recall sends to the AIXHost.exe process, which can continue even after the user closes their Recall session. "The VBS enclave won't decrypt anything without Windows Hello," Hagenah writes. "The tool doesn't bypass that. It makes the user do it, silently rides along when the user does it, or waits for the user to do it." A handful of tasks, including grabbing the most recent Recall screenshot, capturing select metadata about the Recall database, and deleting the user's entire Recall database, can be done with no Windows Hello authentication. Once authenticated, Hagenah says the TotalRecall Reloaded tool can access both new information recorded to the Recall database as well as data Recall has previously recorded. "We appreciate Alexander Hagenah for identifying and responsibly reporting this issue. After careful investigation, we determined that the access patterns demonstrated are consistent with intended protections and existing controls, and do not represent a bypass of a security boundary or unauthorized access to data," a Microsoft spokesperson told Ars. "The authorization period has a timeout and anti-hammering protection that limit the impact of malicious queries."

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