The turn of the century brought about a pressing need for new, efficient and clean strategies for the chemical synthesis of biorelevant compounds. Our group has studied the use of various molecular rearrangements and atom-economical transformations as particularly appealing means towards the streamlined synthesis of complex small molecule targets. In this lecture, we will present an overview of our research in these areas focusing on the chemistries of sulfonium salts, keteniminium ions and small strained rings, and how they provide efficient solutions for the discovery of unusual reactivity or concise total synthesis.
Nuno Maulide was born in Lisbon in 1979. After graduating in chemistry from the Instituto Superior Tecnico in 2003, he completed an M.Sc. at the Ecole Polytechnique in 2004 (Summa cum Laude, ranking 1st out of 22 students) and received his Ph.D. from the Universite catholique de Louvain in 2007.He subsequently moved to Stanford University under Barry M. Trost for postdoctoral studies before returning to Europe to take an endowed position as Max-Planck Research Group Leader at the Max-Planck-Institut fur Kohlenforschung in early 2009, where he also received a prestigious European Research Council (ERC) Starting Grant (2011). Since October 2013 he is Full Professor and Chair of Organic Synthesis at the University of Vienna. His research interests span diverse areas within organic chemistry, focusing on unconventional reaction mechanisms and intermediates. Nuno Maulide has been elected “Scientist of the Year” 2018-19 in Austria and is the youngest Corresponding Member of the Austrian Academy of Sciences. He has received among others the Bayer Early Excellence in Science Award (2012), the ADUC prize of the German Chemical Society (2012), the inaugural EurJOC Young Researcher Award (2015), the Elisabeth Lutz Prize of the Austrian Academy of Sciences (2016) and the Prize of the City of Vienna (2017). Furthermore, he is an ERC Starting (2011), Consolidator (2016) and Proof of Concept (2018) Grantee.