Biophysical chemistry
BIOC 404
Biochemistry: Hydrodynamic and electrophoretic methods for separation and characterization of macromolecules. Optical and magnetic resonance spectroscopy of biopolymers, and applications to biological systems.
Offered by: Biochemistry
- Winter
- Prerequisites: CHEM 204, CHEM 214 or equivalent
- Restriction: Not open to students who have taken or are taking CHEM 404.
- Terms
- Winter 2014
- Instructors
- John R Silvius, William Claude Galley, Miroslaw Cygler
Consult Minerva's Class Schedule for date, time and location.
Lecturers
Dr. John Silvius - 514-398-7267; john [dot] silvius [at] mcgill [dot] ca
Dr. William Galley - 514-398-6928; william [dot] galley [at] mcgill [dot] ca
Dr. Kalle Gehring - 514-398-7287; alle [dot] gehring [at] mcgill [dot] ca
Dr. Mirek Cygler - (BRI) 514-496-6321; mirek [dot] cygler [at] bri [dot] nrc [dot] ca
Evaluation
- Mid-term: 30%
- Final exam: 70%
Course Text
There is no assigned text for this course; readings will be placed in binders that can be signed out (in exchange for your ID card) from the Biochemistry office. Several not-for-credit problem sets (with answers) will be handed out during the course as a study aid.
Topics
- Hydrodynamics
- Sedimentation
- Electrophoresis
- Optical Absorption Spectroscopy
- Fluorescence Spectroscopy
- Mass Spectrometry
- NMR
- X-ray Crystallography
Lecture notes and downloads
Hydrodynamics article 1 Hydrodynamics article 2 Sedimentation article 1 Sedimentation article 2 Electrophoresis article 1 Electrophoresis article 2 (optional) Fluorescence readings 1 Fluorescence readings 2 404 Fluorescence Handout 404 Hydrodynamics Q/A's 404 Sedimentation Q/A’s 404 Fluorescence Correlation Spectroscopy handout 404 Fluorescence Problem Set 404 Fluorescence Problem Set Answers 404 Sedimentation Handout Biochemistry 404 Data Sheet 404 FCS study Q's
Statement on Academic Integrity
"No student shall, with intent to deceive, represent the work of another person as his or her own in any academic writing, essay, thesis, research report, project or assignment submitted in a course or program of study or represent as his or her own an entire essay or work of another, whether the material so represented constitutes a part or the entirety of the work submitted."
