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Biophysical chemistry

BIOC 404

3 credits
Biophysical Methods in Biochemistry.

Biochemistry: Applications and fundamental bases of important biophysical techniques used in modern biochemistry research laboratories to isolate, characterize and determine the structure and dynamics of proteins, nucleic acids, small molecules and complexes that underlie life and disease.

Offered by: Biochemistry

  • Terms
    • Winter 2017
  • Instructors
    • John R Silvius, William Claude Galley, Thomas Martin Schmeing

Lectures

Consult Student Course Calendars for date, time and location.

Evaluation

  • Mid-term: 30%
  • Final exam: 70%

Course Text

There is no assigned text for this course; readings will be placed in binders that can be signed out (in exchange for your ID card) from the Biochemistry office. Several not-for-credit problem sets (with answers) will be handed out during the course as a study aid.

Topics

  • Hydrodynamics
  • Sedimentation
  • Electrophoresis
  • Optical Absorption Spectroscopy
  • Fluorescence Spectroscopy
  • Mass Spectrometry
  • NMR
  • X-ray Crystallography

Lecture notes and downloads


Hydrodynamics article 1 Hydrodynamics article 2 Sedimentation article 1 Sedimentation article 2 Electrophoresis article 1 Electrophoresis article 2 (optional) Fluorescence readings 1 Fluorescence readings 2 404 Fluorescence Handout 404 Hydrodynamics Q/A's 404 Sedimentation Q/A’s 404 Fluorescence Correlation Spectroscopy handout 404 Fluorescence Problem Set 404 Fluorescence Problem Set Answers 404 Sedimentation Handout Biochemistry 404 Data Sheet 404 FCS study Q's

Statement on Academic Integrity

"No student shall, with intent to deceive, represent the work of another person as his or her own in any academic writing, essay, thesis, research report, project or assignment submitted in a course or program of study or represent as his or her own an entire essay or work of another, whether the material so represented constitutes a part or the entirety of the work submitted."