Morgan Craig - Adjunct Professor


Département de mathématiques et de statistique
Université de Montréal
5243, Pavillon André-Aisenstadt
Case postale 6128, succursale Centre-ville
Montréal, QC H3C 3J7

(514) 343-7471

morgan.craig [at] / morgan.craig [at]

Laboratory web site: 

Graduate and summer research positions available

Research Area: Mathematical medicine

Research Description: Broadly speaking, I work in quantitative medicine. My research is focused on constructing mechanistic mathematical models of physiological systems combined with drug models to optimize treatment strategies. My current projects include:

1) various studies of hematopoietic stem cell and neutrophil dynamics in health and disease,

2) PBPK/PD models of antiretroviral drugs to improve HIV treatment and prevention (PrEP) design,

3) the reconstruction of immune networks using dynamical systems techniques to understand how the production or consumption of one cytokine casually influences the up- or down-regulation of another

4) assessing phenotypic adaptive resistance in tumour cell co-cultures using game theoretic approaches

Education:  B.Sc., Université de Saint-Boniface; M.Sc., University of Manitoba, Ph.D., Université de Montréal

Selected Publications:

A.R. Kirtane, O. Abouzid, D. Minaham, T. Bensel, A.L. Hill, C. Selinger, A. Bershteyn, S.S. Mo, M. Craig, H. Mazdiyasni, C. Cleveland, J. Rogner, Y-A. Lee, L. Booth, F. Javid, T. Grant, A.M. Bellinger, B. Nikolic, A. Hayward, L. Wood, P.A. Eckhoff, M. A. Nowak, R. Langer, and G. Traverso. 2018. Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy.Nature Communications, 9, 1, p. 12.

D. Câmara De Souza*, M. Craig*, T. Cassidy, J. Li, F. Nekka, J. Bélair, and A. R. Humphries. 2018. Transit and lifespan in neutrophil production: implications for drug intervention.Journal of Pharmacokinetics and Pharmacodynamics, 45, 1, p. 59-77.[*=Co-first authors]

G.P. Langlois, M. Craig, A. R. Humphries, M. C. Mackey, J.M. Mahaffy, J Bélair, T Moulin, S.R. Sinclair, and L. Wang. 2017. Normal and pathological dynamics of platelets in humans.Journal of Mathematical Biology, 75, 6-7, p. 1141-1462.

M. Craig, A.R. Humphries, and M.C. Mackey. 2016. An upper bound for the half-removal time of neutrophils from the blood.Blood, 128, 15, p. 1989-1991.

M. Craig, A. R. Humphries, and M. C. Mackey. 2016. A mathematical model of granulopoiesis incorporating the negative feedback dynamics and kinetics of G-CSF/neutrophil binding and internalization.Bulletin of Mathematical Biology, 78, 12, p. 2304-2357.

Link to Dr. Craig's publications

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