Associate Professor, Department of Pharmacology & Therapeutics, Department of Oncology
Research in my laboratory focuses on understanding macromolecular structure function relationships, particularly in receptor-ligand interactions.
We have contributed towards the development of protein mimicry technology (reviewed in Nature Biotechnology, 10: 773; Immunomethods 1: 3-12). Using molecular design, biochemistry, and molecular biology techniques large proteins may be dissected to their smallest functional units. These approaches can be adapted for rational drug design and the development of agonists and antagonists.