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McIntyre Medical Sciences Building Tel: 514-398-2181
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Research:
Bastien Castagner obtained a Ph.D. in Chemistry at Columbia University in New York in 2004. His postdoctoral years were spent at ETH Zürich from 2005 - 2008. From 2009 - 2014 he was a Group Leader in the Institute of Pharmaceutical Sciences at ETH Zürich. He joined the Department of Pharmacology & Therapeutics at McGill in 2014 and was promoted to the rank of Associate Professor in 2020.
“Our team includes chemists, pharmacologists, and microbiologists who work closely together to explore new therapeutic avenues. We actively collaborate with other labs with expertise in microbiology, structural biology, computational chemistry, bioinformatics, and oncology to expand our understanding of complex biological systems. With this multidisciplinary approach, we explore novel drugs and therapies to improve the lives of patients.
Our research focuses on the design of small molecules and natural product analogues, with a particular interest in inositol phosphates, carbohydrates, and polyphenols. We are notably developing novel strategies to inactivate the toxins responsible for the pathogenesis of Clostridioides difficile. We are also interested in prebiotic approaches where glycans and polyphenols can enhance the growth of beneficial bacteria in the gut and improve human health, especially in the context of cancer immunotherapy.”