Nicole Yee Key Li-Jessen

Academic title(s): 

Associate Professor
School of Communication Sciences and Disorders

Canada Research Chair in Personalized Medicine of Voice Disorders

Associate Member
Department of Biomedical Engineering
Department of Otolaryngology - Head and Neck Surgery

Nicole Yee Key Li-Jessen
Contact Information
Phone: 
514-398-5933
Address: 

2001 McGill College , 8th floor 
Montreal, Quebec, H3A 1G1

Email address: 
nicole.li [at] mcgill.ca
Department: 
Communication Sciences and Disorders
Areas of expertise: 

Dr. Li-Jessen’s laboratory integrates in vitro, in vivo and in silico (computational) approaches to study vocal fold biology and wound healing. The research goal is to generate a computational platform that can guide surgeons and speech pathologists in the best methods to repair voices that have been lost. Current research projects focus on what cells and proteins drive the vocal fold injury and repair after surgical and vocal trauma, along with the roles of biomechanical stress in cellular and tissue adaptation. Our lab uses agent-based modeling to simulate patient-specific vocal trauma and repair response in computers. In addition, we work in collaboration with engineers and surgeons to develop non-invasive assessment of vocal fold pathology and create biomaterial for vocal fold reconstruction.

Research areas: 
Medical Diagnostics and Therapeutics
Biomolecular and Cellular Engineering
Biomedical Modelling
Bioinformatics and Computational Biology
Area(s): 
System Biology
Human Voice Production
Mechanobiology
Computational Modeling
Diagnosis and Treatment Systems
Non-invasive Diagnostics
Stem Cell Therapy
Inflammation
Tissue Regeneration
Larynx
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