Darcy Wagner

Academic title(s): 

Professor, Department of Biomedical Engineering

Professor, Department of Medicine, Division of Experimental Medicine

Canada Excellence Research Chair in Lung Regenerative Medicine

Faculty, Meakins-Christie Laboratories (Meakins)

Scientist, Translational Research in Respiratory Diseases Program (RESP) at the Research Institute of the McGill University Health Centre (RI-MUHC)

Principal Investigator, McGill Regenerative Medicine Network (MRM Network)

Darcy Wagner
Contact Information

Research Institute of the McGill University Health Centre

1001 Décarie Blvd., Block E, Montreal, QC, CANADA H4A 3J1

Email address: 
darcy.wagner [at] mcgill.ca
Biomedical Engineering
Experimental Medicine
Areas of expertise: 

Our lab focuses on how the extracellular environment directs stem cell behavior for endogenous and exogenous lung tissue regeneration. We use a multidisciplinary approach using advances in materials science (polymer design and synthesis), manufacturing (e.g. 3D bioprinting), and endogenous and iPSC-derived lung stem cells to construct these new models.

The main areas of interest of the lab are:

  • Design and use of biologic (acellular) and synthetic scaffolds in diverse manufacturing approaches to bioengineer new lung tissue for transplantation.

  • Understand the role of the extracellular matrix in directing lung stem cell behaviour in vivo and ex vivo during regeneration (normal and pathologic)

  • Build and validate new models of human lung tissue and chronic lung disease to reduce animal usage and for use as drug discovery and therapeutic screening platforms

Keywords: bioengineering, lung regeneration, biomaterials, stem cells, bioprinting, microfluidics, light sheet fluorescence microscopy, image analysis

Research areas: 
Biomaterials and Tissue Engineering
Biomolecular and Cellular Engineering
Imaging and Microscopy
Bioinformatics and Computational Biology
Tissue Engineering
Porous Biomaterials
Green Chemistry
Image Processing
Regenerative Medicine
Next-generation Sequencing (NGS)
3-D and 4-D Imaging
Stem Cell Therapy
3D Printing
Tissue Regeneration
Light Sheet Fluorescence Microscopy (LSFM)
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