Patricia Pelufo Silveira, MD, PhD

Patricia Pelufo Silveira

Associate Professor
Douglas Mental Health University Institute

Phone icon +1 514-761-6131 ext 2776
Email icon: patricia.silveira [at]




  • Associate Professor, Department of Psychiatry, McGill University;
  • Associate Director of McGill’s Integrated Program in Neuroscience (IPN);
  • Researcher and Lead for the Environmental Adversity, Neurodevelopment and Mental Health research group, Douglas Mental Health University Institute;
  • Scientific Director, Ludmer Centre for Neuroinformatics & Mental Health.

Patricia Pelufo Silveira, MD, PhD, is a professor in the department of Psychiatry, and is the associate director of the McGill Integrated Program in Neuroscience (IPN). Her research focuses on how perinatal and early-childhood environments can shape and modulate both health and disease across the lifespan, into old age. Dr. Silveira's aim is to identify genetic/epigenetic markers that interact with environmental adversities in childhood, modifying behaviours (impulsivity, sensitivity to reward, food choices) that ultimately affect healthy growth and neurodevelopment and increasing an individual’s risk for developing chronic diseases and mental illnesses as they age.

Dr. Silveira created a biologically informed methodology, expression-based Polygenic Risk Scores (ePRS), which is now an open source service company offering scientific consulting and a wide range of genomic services for both academia and industry. Her unique approach focuses on gene networks, rather than individual genes or single-genetic-variations, and enables the exploitation of under-utilised genetic data collected by most studies exploring the impact of early life adversities. 

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