See Edward Fon's full bibliography here
Selected Preprints
MacDougall EJ, Chen CXQ, Deneault E, You Z, Abdian N, Durcan TM, Senkevich K, Gan-Or Z, Fon EA. LRRK2 Kinase Mediates Increased GCase Activity in Microglia in Response to Proinflammatory Stimuli. [See the preprint]
Deyab G, Thomas RA, Ding XE, Li J, Sirois J, Al-Azzawi Z, Niu S, Durcan TM, Fon EA. Midbrain organoids with an SNCA gene triplication display dopamine-dependent alterations in network activity. [See the preprint]
Del Cid-Pellitero E, Goiran T, Al-Azzawi ZAM, Karpilovsky NC, Jones-Tabah J, Mayo JJ, Larroquette F, Luo W, Shlaifer I, Thattikota Y, Bayne A, Trempe JF, Durcan TM, Fon EA. N-terminal acetylation reduces α-synuclein pathology in models of Parkinson’s disease. [See the preprint]
Thomas RA, Cai E, Reintsch W, Han C, Shinde S, Larivière R, Krahn A, Chen CXQ, Nguyen-Renou E, Deneault E, You Z, Durcan TM, Fon EA. MA deep learning convolutional neural network distinguishes neuronal models of Parkinson’s disease from matched controls. [See the preprint]
Selected Published articles
Al-Azzawi ZAM, Silver NRG, Niu S, Luo W, Shlaifer I, Ingelsson M, Hyman BT, Trempe JF, Durcan TM, Watts JC, Fon EA. α-Synuclein purification significantly impacts seed amplification assay performance and consistency. Acta Neuropath Commun. 2025 [Read the paper]
Fiorini MR, Li J, Fon EA, Farhan SMK, Thomas RA. Neural networks reveal novel gene signatures in Parkinson disease from single-nuclei transcriptomes. NPJ Parkinsons Dis. 2025 [Read the paper]
Vanderperre B, Muraleedharan A, Dorion MF, Larroquette F, Del Cid Pellitero E, Rajakulendran N, Chen CXQ, Larivière R, Michaud-Tardif C, Chidiac R, Lipuma D, MacLeod G, Thomas RA, Wang Z, Reintsch WE, Luo W, Shlaifer I, Zhang F, Xia K, Yan L, Steinhart Z, Linhardt RJ, Trempe JF, Liu J, Durcan TM, Angers S, Fon EA. Novel regulators of heparan sulfate proteoglycans modulate cellular uptake of α-synuclein fibrils. Commun Biol. 2025 [Read the paper]
Fiorini MR, Amiri S, Dilliott AA, Ohki CMY, Smigielski L, Walitza S, Fon EA, Grünblatt E, Thomas RA, Farhan SMK. Ensemblex: an accuracy-weighted ensemble genetic demultiplexing framework for population-scale scRNAseq sample pooling. Genome Biol. 2025 [Read the paper]
Eldeeb MA, Shahid M, Fon EA. Cell biology: Mitochondrial protease degrades unoccupied translocases upon import stress. Curr Biol. 2025 [Read the paper]
Jones-Tabah J, He K, Karpilovsky N, Senkevich K, Deyab G, Goiran T, Pietrantonio I, Cousineau Y, Nikanorova D, Goldsmith T, Del Cid Pellitero E, Chen CXQ, Luo W, You Z, Abdian N, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Waters C, Monchi O, Dauvilliers Y, Dupré N, Miliukhina I, Timofeeva A, Emelyanov A, Pchelina S, Greenbaum L, Hassin-Baer S, Alcalay RN, Milnerwood A, Durcan TM, Gan-Or Z, Fon EA. The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons. Mol. Neurodegeneration. 2024 [Read the paper]
Eldeeb MA, Bayne AN, Fallahi A, Goiran T, MacDougall EJ, Soumbasis A, Zorca CE, Jones Tabah J, Thomas RA, Karpilovsky N, Mathur M, Durcan TM, Trempe JF, Fon EA. TOM20 Gates PINK1 Activity And Mediates Its Tethering Of The TOM And TIM23 Translocases Upon Mitochondrial Stress. Proc Natl Acad Sci USA 2024 [Read the paper]
Thomas RA, Sirois J, Li S, Gestin A, Deyab G, Piscopo VE, Lépine P, Mathur M, Chen CXQ, Soubannier V, Goldsmith TM, Fawaz L, Durcan TM, Fon EA. CelltypeR: A flow cytometry pipeline to annotate, characterize and isolate single cells from brain organoids. iScience 2024 [Read the paper]
Dorion MF, Yaqubi M, Senkevich K, Kieran NW, MacDonald A, Chen CX, Luo W, Wallis A, Shlaifer I, Hall JA, Dudley RWR, Glass IA; Birth Defects Research Laboratory; Stratton JA, Fon EA, Bartels T, Antel JP, Gan-Or Z, Durcan TM, Healy LM. MerTK is a mediator of alpha-synuclein fibril uptake by human microglia. Brain 2023 [Read the paper]
Yu E, Lariviere R, Thomas RA, Liu L, Senkevich K, Rahayel S, Trempe JF, Fon EA, Gan-Or Z. Machine learning nominates the inositol pathway and novel genes in Parkinson’s disease. Brain 2023 Oct 10:1093/awad345. [Read the paper]
Senkevich K, Zorca CE, Dworkind A, Rudakou U, Somerville E, Yu E, Ermolaev A, Nikanorova D, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Fahn S, Waters C, Monchi O, Dauvilliers Y, Dupré N, Greenbaum L, Hassin-Baer S, Grenn FP, Chiang MSR, Sardi SP, Vanderperre B, Blauwendraat C, Trempe JF, Fon EA, Durcan TM, Alcalay RN, Gan-Or Z. GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson's disease. Brain 2023 [Read the paper]
Bayati A, Luo W, Del Cid-Pellitero E, Fon EA, Durcan TM, McPherson PS. Visualization of α-synuclein trafficking via nanogold labeling and electron microscopy. STAR Protoc. 2023 [Read the paper]
Stevens MU, Croteau N, Eldeeb MA, Antico O, Zeng ZW, Toth R, Durcan TM, Springer W, Fon EA, Muqit MM, Trempe JF. Structure-based design and characterization of Parkin-activating mutations. Life Sci Alliance. 2023 [Read the paper]
Eldeeb MA, Eldeeb MA, Soumbasis A, Fon EA. How does mitochondrial import machinery fine-tune mitophagy? Different paths and one destination. Trends Endocrinol Metab. 2023 [Read the paper]
Sheta R, Teixeira M, Idi W, Pierre M, de Rus Jacquet A, Emond V, Zorca CE, Vanderperre B, Durcan TM, Fon EA, Calon F, Chahine M, Oueslati A. Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons. Sci Rep. 2022 [Read the paper]
Lackie RE, de Miranda AS, Lim MP, Novikov V, Madrer N, Karunatilleke NC, Rutledge BS, Tullo S, Brickenden A, Maitland MER, Greenberg D, Gallino D, Luo W, Attaran A, Shlaifer I, Del Cid Pellitero E, Schild-Poulter C, Durcan TM, Fon EA, Duennwald M, Beraldo FH, Chakravarty MM, Bussey TJ, Saksida LM, Soreq H, Choy WY, Prado VF, Prado MAM. Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo. Acta Neuropathol. 2022 [Read the paper]
Bayati A, Banks E, Han C, Luo W, Reintsch WE, Zorca CE, Shlaifer I, Del Cid Pellitero E, Vanderperre B, McBride HM, Fon EA, Durcan TM, McPherson PS. Rapid macropinocytic transfer of α-synuclein to lysosomes. Cell Rep. 2022 [Read the paper]
Goiran T, Eldeeb MA, Zorca CE, Fon EA. Hallmarks and Molecular Tools for the Study of Mitophagy in Parkinson's Disease. Cells 2022 [Read the paper]
Sauvé V, Sung G, MacDougall EJ, Kozlov G, Saran A, Fakih R, Fon EA, Gehring K. Structural basis for feedforward control in the PINK1/Parkin pathway. EMBO J. 2022 [Read the paper]
Eldeeb MA, Thomas RA, Ragheb MA, Fallahi A, Fon EA. Mitochondrial quality control in health and in Parkinson's disease. Physiol Rev 2022 [Read the paper]
Dong J, Duchesne A, Bayne AN, Mohamed NV, Yi W, Mathur M, Chen CXQ, You Z, Abdian N, Taylor L, Fon EA, Durcan TM, Trempe JF. An approach to measuring protein turnover in human induced pluripotent stem cell organoids by mass spectrometry. Methods 2022 [Read the paper]
Bérard M, Sheta R, Malvaut S, Rodriguez-Aller R, Teixeira M, Idi W, Turmel R, Alpaugh M, Dubois M, Dahmene M, Salesse C, Lamontagne-Proulx J, St-Pierre MK, Tavassoly O, Luo W, Del Cid-Pellitero E, Qazi R, Jeong JW, Durcan TM, Vallières L, Tremblay ME, Soulet D, Lévesque M, Cicchetti F, Fon EA, Saghatelyan A, Oueslati A. A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease. PLoS Biol. 2022 [Read the paper]
Rasool S, Veyron S, Soya N, Eldeeb MA, Lukacs GL, Fon EA, Trempe JF. Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex. Mol Cell. 2022 [Read the paper]
Tavassoly O*, Del Cid-Pellitero E*, Larroquette F, Cai E, Thomas RA, Soubannier V, Luo W, Durcan TM, Fon EA. Pharmacological Inhibition of Brain EGFR Activation By a BBB-penetrating Inhibitor, AZD3759, Attenuates α-synuclein Pathology in a Mouse Model of α-Synuclein Propagation. Neurotherapeutics 2021 *First co-authors [Read the paper]
Jin JW*, Fan X*, Del Cid-Pellitero E*, Liu XX, Zhou L, Dai C, Gibbs E, He W, Li H, Wu X, Hill A, Leavitt BR, Cashman N, Liu L, Lu J, Durcan TM, Dong Z, Fon EA & Wang YT. Development of an α-synuclein knockdown peptide and evaluation of its efficacy in Parkinson’s disease models. Communications Biology 2021 *First co-authors [Read the paper]
Roberts R., Bayne AN., Goiran T., Lévesque D., Boisvert FM., Trempe JF., Fon EA. Proteomic Profiling of Mitochondrial-Derived Vesicles in Brain Reveals Enrichment of Respiratory Complex Sub-assemblies and Small TIM Chaperones. J Proteome Res 2021 [Read the paper]
Jefri M, Bell S, Peng H, Hettige N, Maussion G, Soubannier V, Wu H, Silveira H, Theroux JF, Moquin L, Zhang X, Aouabed Z, Krishnan J, O'Leary LA, Antonyan L, Zhang Y, McCarty V, Mechawar N, Gratton A, Schuppert A, Durcan TM, Fon EA, Ernst C. Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells. Stem Cells Transl Med. 2020 [Read the paper]
Martínez GF, Gazal NG, Quassollo G, Szalai AM, Cid-Pellitero ED, Durcan TM, Fon EA, Bisbal M, Stefani FD, Unsain N. Quantitative expansion microscopy for the characterization of the spectrin periodic skeleton of axons using fluorescence microscopy. Sci. Rep. 2020;10(1):2917. [Read the paper]
Gan-Or Z, Rao T, Leveille E, Degroot C, Chouinard S, Cicchetti F, Dagher A, Das S, Desautels A, Drouin-Ouellet J, Durcan T, Gagnon JF, Genge A, Karamchandani J, Lafontaine AL, Sun SLW, Langlois M, Levesque M, Melmed C, Panisset M, Parent M, Poline JB, Postuma RB, Pourcher E, Rouleau GA, Sharp M, Monchi O, Dupré N, Fon EA. The Quebec Parkinson Network: A Researcher-Patient Matching Platform and Multimodal Biorepository. J Parkinsons Dis. 2020;10(1):301-313 [Read the paper]
Eldeeb MA, MacDougall EJ, Ragheb MA, Fon EA. Beyond ER: Regulating TOM-Complex-Mediated Import by Ubx2. Trends Cell Biol. 2019;29(9):687-689 [Read the paper]
Fava VM, Xu YZ, Lettre G, Van Thuc N, Orlova M, Thai VH, Tao S, Croteau N, Eldeeb MA, MacDougall EJ, Cambri G, Lahiri R, Adams L, Fon EA, Trempe JF, Cobat A, Alcaïs A, Abel L, Schurr E. Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease. Proc Natl Acad Sci U S A. 2019;116(31):15616-15624 [Read the paper]
Eldeeb MA, Ragheb MA, Fon EA. Cell Death: N-degrons Fine-Tune Pyroptotic Cell Demise. Curr Biol. 2019;29(12):R588-R591 [Read the paper]
Eldeeb MA, Fahlman RP, Esmaili M, Fon EA. When Degradation Elicits the Alarm: N-Terminal Degradation of NLRP1B Unleashes Its Inflammasome Activity. Mol Cell. 2019;74(4):637-639 [Read the paper]
Yi W, MacDougall EJ, Tang MY, Krahn AI, Gan-Or Z, Trempe JF, Fon EA. The landscape of Parkin variants reveals pathogenic mechanisms and therapeutic targets in Parkinson's disease. Hum Mol Genet. 2019;28(17):2811-2825 [Read the paper]
Alcalay RN, Mallett V, Vanderperre B, Tavassoly O, Dauvilliers Y, Wu RYJ, Ruskey JA, Leblond CS, Ambalavanan A, Laurent SB, Spiegelman D, Dionne-Laporte A, Liong C, Levy OA, Fahn S, Waters C, Kuo SH, Chung WK, Ford B, Marder KS, Kang UJ, Hassin-Baer S, Greenbaum L, Trempe JF, Wolf P, Oliva P, Zhang XK, Clark LN, Langlois M, Dion PA, Fon EA, Dupre N, Rouleau GA, Gan-Or Z. SMPD1 mutations, activity, and α-synuclein accumulation in Parkinson's disease. Mov Disord. 2019;34(4):526-535 [Read the paper]
Mohamed NV, Mathur M, Da Silva RV, Beitel LK, Fon EA, Durcan TM. Generation of human midbrain organoids from induced pluripotent stem cells. MNI Open Research 2019 [Read the paper]
Mohamed NV, Larroquette F, Beitel LK, Fon EA, Durcan TM. One Step Into the Future: New iPSC Tools to Advance Research in Parkinson's Disease and Neurological Disorders. J Parkinsons Dis. 2019;9(2):265-281 [Read the paper]
Eldeeb MA*, Fahlman RP, Esmalili M, Fon EA. Formylation of Eukaryotic Cytoplasmic Proteins:Linking Stress to Degradation. Trends Biochem, Sci. 2019; 181-183 [Read the paper]
Rudakou U, Ouled Amar Bencheikh B, Ruskey JA, Krohn L, Laurent SB, Spiegelman D, Liong C, Fahn S, Waters C, Monchi O, Fon EA, Dauvilliers Y, Alcalay RN, Dupré N, Gan-Or Z. Common and rare GCH1 variants are associated with Parkinson's disease. Neurobiol. Aging. 2019; 73:231.e1-231.e6. [Read the paper]
McLelland GL*, Fon EA. MFN2 retrotranslocation boosts mitophagy by uncoupling mitochondria from the ER. Autophagy. 2018; 1658-1660. [Read the paper]
McLelland GL*, Fon EA. Principles of mitochondrial vesicle transport. Curr. Opin. Physiol. 2018; 3:25–33. [Read the paper]
Ouled Amar Bencheikh B, Leveille E, Ruskey JA, Spiegelman D, Liong C, Fon EA, Rouleau GA, Dauvilliers Y, Dupre N, Alcalay RN, Gan-Or Z. Sequencing of the GBA coactivator, Saposin C, in Parkinson disease. Neurobiol. Aging. 2018; S0197-4580(18)30239-2.–33. [Read the paper]
Ruskey JA, Zhou S, Santiago R, Franche LA, Alam A, Roncière L, Spiegelman D, Fon EA, Trempe JF, Kalia LV, Postuma RB, Dupre N, Rivard GE, Assouline S, Amato D, Gan-Or Z. The GBA p.Trp378Gly mutation is a probable French-Canadian founder mutation causing Gaucher disease and synucleinopathies. Clin. Genet. 2018; [Read the paper]
Bell S, Maussion G, Jefri M, Peng H, Theroux JF, Silveira H, Soubannier V, Wu H, Hu P, Galat E, Torres-Platas SG, Boudreau-Pinsonneault C, O'Leary LA, Galat V, Turecki G, Durcan TM, Fon EA, Mechawar N, Ernst C. Disruption of GRIN2B Impairs Differentiation in Human Neurons. Stem Cell Reports. 2018; S2213-6711(18)30236-4 [Read the paper]
Li J, Ruskey JA, Arnulf I, Dauvilliers Y, Hu MTM, Högl B, Leblond CS, Zhou S, Ambalavanan A, Ross JP, Bourassa CV, Spiegelman D, Laurent SB, Stefani A, Charley Monaca C, Cochen De Cock V, Boivin M, Ferini-Strambi L, Plazzi G, Antelmi E, Young P, Heidbreder A, Labbe C, Ferman TJ, Dion PA, Fan D, Desautels A, Gagnon JF, Dupré N, Fon EA, Montplaisir JY, Boeve BF, Postuma RB, Rouleau GA, Ross OA and Gan-Or Z. Full sequencing and haplotype analysis of MAPT in Parkinson disease and REM sleep behavior disorder. Mov. Disord. 2018; [Read the paper]
McLelland GL*, Goiran T*, Yi W*, Dorval G, Chen CX, Lauinger ND*, Krahn AI*, Valimehr S, Rakovic A, Rouiller I, Durcan TM, Trempe JF, Fon EA. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. Elife. 2018; 7.pii: e32866. [Read the paper]
Mohtashami S, He Q, Ruskey JA, Zhou S, Dion PA, Allen RP, Earley CJ, Fon EA, Xiong L, Dupre N, Dauvilliers Y, Rouleau GA, Gan-Or Z. TOX3 Variants Are Involved in Restless Legs Syndrome and Parkinson's Disease with Opposite Effects. J. Mol. Neurosci. 2018; 64(3):341-345. [Read the paper]
Ross JP, Mohtashami S, Leveille E, Johnson AM, Xiong L, Dion PA, Fon EA, Dauvilliers Y, Dupré N, Rouleau GA, Gan-Or Z. Association study of essential tremor genetic loci in Parkinson's disease. Neurobiol. Aging. 2018; 66:178.e13-178.e15. [Read the paper]
Manecka DL*, Vanderperre B*, Fon EA, Durcan TM. The Neuroprotective Role of Protein Quality Control in Halting the Development of Alpha-Synuclein Pathology. Front. Mol. Neurosci. 2017; 10: 311. [Read the paper]
Tang MY*, Vranas M, Krahn A*, Pundlik S*, Trempe JF, Fon EA. Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation. Nat. Commun. 2017; 8: 14697. [Read the paper]
Rodriguez L, Mohamed NV, Desjardins A, Lippé R, Fon EA, Leclerc N. Rab7A regulates Tau secretion. J. Neurochem. 2017; 141(4):592-605. [Read the paper]
Roberts RF*, Fon EA. Presenting mitochondrial antigens: PINK1, Parkin and MDVs steal the show. Cell Res. 2016; 26(11):1180-1181. [Read the paper]
Roberts RF*, Tang MY*, Fon EA, Durcan TM. Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles. Int. J. Biochem. Cell. Biol. 2016; 79:427-436. [Read the paper]
Munoz DP, Fon EA, Chen R. A New Collaboration Between the Canadian Association for Neuroscience and CJNS. Can. J. Neurol. Sci. 2016; 43(1):2. [Read the paper]
McLelland GL*, Lee SA*, McBride HM, Fon EA. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. J. Cell Biol. 2016; 214(3):275-91. [Read the paper]
Schreij AM, Fon EA, McPherson PS. Endocytic membrane trafficking and neurodegenerative disease. Cell. Mol. Life Sci. 2016; 73(8):1529-45. [Read the paper]
Durcan TM*, Fon EA. The three P’s of Mitophagy: PARKIN, PINK1 and Post-Translational Modifications. Genes Dev. 2015; 29(10):989-999. [Read the paper]
Ryan BJ, Hoek S, Fon EA, Wade-Martins R. Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease. Trends Biochem. Sci. 2015; 40(4):200-210. [Read the paper]
Durcan TM*, Fon EA. USP8 and PARK2/parkin-mediated mitophagy. Autophagy. 2015; 11(2):428-9. [Read the paper]
Aguileta MA*, Korac J, Durcan TM*, Trempe JF*, Haber M*, Gehring K, Elsasser S, Waidmann O, Fon EA, Husnjak K. The E3 Ubiquitin ligase parkin is recruited to the 26S proteasome via the proteasomal ubiquitin receptor Rpn13. J Biol Chem. 2015; 290(12):7492-505. [Read the paper]
Bertolin G, Jacoupy M, Traver S, Ferrando-Miguel R, Saint Georges T, Grenier K*, Ardila-Osorio H, Muriel MP, Takahashi H, Lees AJ, Gautier C, Guedin D, Coge F, Fon EA, Brice A, Corti O. Parkin maintains mitochondrial levels of the protective Parkinson's disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10. Cell Death Differ. 2015; 22(10):1563-76. [Read the paper]
Schreij AMA*, Chaineau M, Ruan W, Lin S, Barker, PA, Fon EA§, McPherson PS§. LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation. EMBO Rep. 2015; 16(1):79-86. §co-corresponding authors [Read the paper]
Grenier K*, Kontogiannea M*, Fon EA. Short mitochondrial ARF triggers Parkin/PINK1-dependent mitophagy in neurons. J. Biol. Chem. 2014; 289(43):29519-30 [Read the paper]
Durcan TM*, Tang MY*, Pérusse JR, Dashti EA*, Aguileta MA*, McLelland GL*, Gros P*, Shaler TA, Faubert D, Coulombe B, Fon EA. USP8 Regulates Mitophagy by Removing K6-linked Ubiquitin Conjugates from Parkin. EMBO J. 2014; 33(21):2473-91 [Read the paper]
Sugiura A, McLelland GL*, Fon EA, McBride HM. A new Pathway for Mitochondrial Quality Control: Mitochondrial Derived Vesicles. EMBO J. 2014; 33(19):2142-2156 [Read the paper]
Koyano F, Okatsu K, Kosako H, Tamura Y, Go E, Kimura M, Kimura Y, Tsuchiya H, Yoshihara H, Hirokawa T, Endo T, Fon EA, Trempe JF, Saeki Y, Tanaka K, Matsuda N. Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature. 2014; 510(7503):162-6 [Read the paper]
McLelland GL*, Soubannier V, Chen CX*, McBride HM, Fon EA. Parkin and PINK1 Function in a Vesicular Trafficking Pathway Regulating Mitochondrial Quality Control. EMBO J. 2014; 33(4):282-95. [Read the paper]
Bertolin G, Ferrando-Miguel R, Jacoupy M, Traver S, Grenier K*, Greene AW*, Dauphin A, Waharte F, Bayot A, Salamero J, Lombès A, Bulteau AL, Fon EA, Brice A, Corti O. The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance. Autophagy. 2013; 9(11):1801-17 [Read the paper]
Grenier K*, McLelland GL*, Fon EA. Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up? Front Neurol. 2013; 4:100 [Read the paper]
Trempe J-F*, Sauvé, V*, Grenier K, Seirafi, M, Tang MY, Ménade M, Krett J, Wong K, Kozlov G, Nagar B, Fon EA§, Gehring K§. Structure of parkin reveals mechanism of ubiquitin ligase activation. Science. 2013; 340: 1451-55 Epub 2013 May 9. §co-corresponding authors. [Read the paper]
