Associate Professor - Reproductive biologyT: 514-398-7793 | vilceu.bordignon [at] mcgill.ca (Email) | Macdonald-Stewart Building, MS1-089 |
Degrees
DVM (Universidade da Região da Campanha (Brazil))
PhD (Université de Montréal)
Short Bio
Vilceu Bordignon obtained his PhD in 1999 and postdoctoral training in 2002 in biomedical sciences at the University of Montreal, following his DVM and MSc in veterinary sciences in Brazil. He joined McGill’s Department of Animal Science in July 2002. His is the Director of the McGill Large Animal Research Unit. His lab produced the first cloned and transgenic pigs in Canada by somatic cell nuclear transfer. His current research program in reproductive biology and animal biotechnology is: i) investigating how early stage embryos deal with stressful conditions by regulating coping mechanisms that allow them to survive without passing on altered or damaged genomes that threaten development and later life; ii) studying how cell reprogramming is regulated in embryos produced by somatic cell nuclear transfer; and iii) using genome editing tools (CRISPR/Cas system) along with in vitro embryo technologies and somatic cell nuclear transfer to create gene edited embryos and live pigs to study development, metabolism and pathophysiology mechanisms.
Active Affiliations
Member of the McGill Centre for Research in Reproduction and Development – CRRD
Member of the Réseau Québécois en Reproduction – RQR
Member of the International Embryo Technology Society (IETS)
Member of the Society for the Study of Reproduction – SSR
Research Interests
- Somatic cell reprogramming
- Oocyte and embryo development
- Nuclear transfer and animal cloning
- Creation of swine models for biomedical research
Current Research
- DNA damage and endoplasmic reticulum stress during early embryo development.
- Acquisition of developmental competence in oocyte and embryos.
- Cell reprogramming and embryos produced by somatic cell nuclear transfer.
- Genome editing in swine.
Courses
Graduate students (current)
rodrigo.bohrer [at] mail.mcgill.ca (Rodrigo C. Bohrer), PhD candidate
naomi.dicks [at] mail.mcgill.ca (Naomi Dicks), PhD candidate
karina.gutierrez [at] mail.mcgill.ca (Karina Gutierrez) – PhD camdidate
rosalba.lopez [at] mail.mcgill.ca (Rosalba Lopez )– MSc student
mariana.priottodemacedo [at] mail.mcgill.ca (Mariana Priotto De Macedo) - MSc student
palunardelli [at] hotmail.com (Paula Alvares Lunardelli), Visiting Research Student (PhD) from the University of Londrina, Parana State, Brazil
Visiting Researchers
wernergiehl [at] gmail.com (Werner Giehl Glanzner), Visiting Research Student (PhD) from the Federal University of Santa Maria, Brazil