Mikaela Stiver won an Innovations Program Grant from the American Association for Anatomy.
Neuroanatomy is in the Cards for Member Mikaela Stiver
There are collectible trading card games for almost everything these days. Besides Pokémon, there are, of course, cards for athletes, celebrities, TV and movie characters, and musical instruments, just to name a few.
Dr. Strauss publishes article in the Journal of Cell Biology: Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain
Glucose homeostasis and growth essentially depend on the hormone insulin engaging its receptor. Despite biochemical and structural advances, a fundamental contradiction has persisted in the current understanding of insulin ligand–receptor interactions. While biochemistry predicts two distinct insulin binding sites, 1 and 2, recent structural analyses have resolved only site 1.
Dr. Charles E. Smith continues long-standing collaborative investigations with Dr. James Simmer and Dr. Jan Hu from the University of Michigan
Dr. Charles E. Smith continues long-standing collaborative investigations with Dr. James Simmer and Dr. Jan Hu from the University of Michigan about how ameloblasts coordinate their activities to produce the protective enamel covering of teeth as well as flawed responses that occur from these cells when matrix formation/signaling is disrupted by genetic alterations.
Below is a list of recent publications:
Dr. McPherson's Lab has developed a protocol to easily assess the specificity of antibodies—and hopefully stem some of the reproducibility crisis.
Peter S. McPherson
Opinion: Scientists Need to Demand Better Antibody ValidationMy lab has developed a protocol to easily assess the specificity of antibodies—and hopefully stem some of the reproducibility crisis.
Click here to read the full article.
Reinhardt lab receives funding from the prestigious Marfan Foundation (USA) to explore the connection between diet and disease development in Marfan syndrome
Reinhardt lab receives funding from the prestigious Marfan Foundation (USA) to explore the connection between diet and disease development in Marfan syndrome. Congratulations!
Dr. Sandra Miller published an article in Current Trends in Immunology
TITLE: Augmentation of cell numbers and function in the immune system by in vivo administration of North American (NA) ginseng (Panax Quinquefolium): Assessment in normal and cancer-bearing infant, juvenile, adult and elderly mice
Reinhardt lab published new mechanisms in elastic fiber formation in the Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Title: Fibulin-4 exerts a dual role in LTBP-4L–mediated matrix assembly and function
Amal Seffouh, a Postdoctoral Fellow in the Ortega lab, publishes her most recent work about the role of RbgA in the maturation of the 50S ribosomal subunit
Amal Seffouh, a Postdoctoral Fellow in the Ortega lab, publishes her most recent work about the role of RbgA in the maturation of the 50S ribosomal subunit.
Click here to read the paper.
Congratulations to Dr. Marc McKee for receiving the ASBMR 2019 Adele L. Boskey Award!
Congratulations to Dr. Marc McKee for receiving the ASBMR 2019 Adele L. Boskey Award! The Adele L Boskey Esteemed Award for Bone and Mineral Research recognizes an American Society for Bone and Mineral Research member for outstanding and major scientific contributions, leadership and mentorship in the area of bone and mineral research especially in the areas of mechanisms of mineralization, bone mineral, bone quality, and mechanobiology.
Aida Razi’s last PhD thesis chapter now published online in the Nucleic Acids Research journal. This publication features the first cryo-EM structures obtained by the Ortega lab in the Titan Krios microscope at FEMR-McGill
Aida Razi’s last PhD thesis chapter now published online in the Nucleic Acids Research journal. This publication features the first cryo-EM structures obtained by the Ortega lab in the Titan Krios microscope at FEMR-McGill.
Read the paper at https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz571/5527280?searchresult=1
Dr. Kelly Sears is awarded the Microscopical Society of Canada Technologist Award 2019
Dr. Kelly Sears, Research Manager at the Facility for Electron Microscopy Research (FEMR) is awarded the Microscopical Society of Canada Technologist Award 2019. This award recognizes his passion and dedication to FEMR research mission. Congratulations!
Deanna MacNeil from the Autexier lab establishes how an imbalance favoring telomerase RNA degradation over correct maturation is causative for the premature aging telomere biology disorder dyskeratosis congenita.
The telomerase holoenzyme responsible for maintaining telomeres in vertebrates requires many components in vivo, including dyskerin. Dyskerin binds and regulates the accumulation of the human telomerase RNA, hTR, as well as other non-coding RNAs that share the conserved H/ACA box motif.
Reinhardt lab receives 5-year CIHR grant to investigate extracellular matrix-mediated regulation of microRNAs in health and disease.
Reinhardt lab receives 5-year CIHR grant to investigate extracellular matrix-mediated regulation of microRNAs in health and disease. Congratulations!
Reinhardt lab establishes a new paradigm how extracellular fibrillin-1 regulates intracellular microRNAs and cell function
Fibrillins are the major components of microfibrils in the extracellular matrix of elastic and non-elastic tissues. Fibrillin-1 contains one evolutionarily conserved RGD sequence that mediates cell–matrix interactions through cell-surface integrins. The Reinhardt lab presents a novel paradigm how extracellular fibrillin-1 controls cellular function through integrin-mediated microRNA regulation.