New publication from the Bui Lab in Current Biology on cilia tip structure
Motile cilia are specialized organelles essential for cell movement and fluid flow, driven by the beating of their internal cytoskeleton called the axoneme. At the core of the axoneme lies the central pair (CP) of microtubules, which features a distinct distal tip structure critical for motility. However, the proteins stabilizing this region have remained largely unknown.
New publication in Science from the Bernard lab with former and current Cell Biology graduate students Emilie Brûlé and Hailey Schultz
Myostatin is a paracrine myokine that regulates muscle mass in a variety of species, including humans. In this work, they report a functional role for myostatin as an endocrine hormone that directly promotes pituitary follicle-stimulating hormone (FSH) synthesis and thereby ovarian function in mice. Previously, this FSH-stimulating role was attributed to other members of the transforming growth factor-β family, the activins.
Celebrating Dedication & Commitment
Honoring our incredible team members for their years of service and dedication! 💙👏 Your hard work and passion make all the difference. Here's to many more milestones ahead! ✨ #StaffAppreciation #MilestoneMoments #TeamExcellence
Prof. Venne awarded the 2024 President's Prize for Excellence in Teaching
Prof. Gabriel Venne, Director of the Division of Anatomical Sciences, has been awarded the 2024 President's Prize for Excellence in Teaching. Pictured here is Prof. Venne receiving his award from McGill President Deep Saini at the Fall Convocation ceremony on Dec. 2nd.
Congratulations to Prof. Davis!
Last week, ACB had the opportunity to celebrate the retirement of Professor Elaine Davis, who has worked in the department for over twenty years. Congratulations to Prof. Davis!
Pictured from left to right: Carlos Morales, Hojatollah Vali, Elaine Davis, Chantal Autexier, Craig Mandato, and Gabriel Venne.
Anatomy & Cell Biology Scientific Image Contest: Winners Announced!
This summer, department members participated in our inaugural Scientific Image Contest: "Life Magnified: An Anatomy and Cell Biology Exploration."
Prof. Venne is the 2024 recipient of the Osler Award for Outstanding Teaching in the Faculty of Medicine and Health Sciences
Congratulations to Prof. Venne for this accomplishment!
Congratulations to our undergraduate scholarship winners!
Prof. Charles E. Smith has received an honorary doctorate from L'Université Laval
Congratulations to Prof. Charles E. Smith on receiving an honorary doctorate from L'Université Laval!
Pictured is Prof. Smith holding his award with the Secretary General (right side, Monique Richer), the Dean of the Dental School (Petros Papagerakis, left side), and the Rector (in red gown, Sophie D’Amours) of Université Laval.
New publication from the Reinhardt and Strauss labs
Two faculty members of the Department of Anatomy and Cell Biology joined forces to bridge the field of cryo-electron microscopy (Mike Strauss) and extracellular matrix cell biology (Dieter Reinhardt). This interdisciplinary team also spanned faculties across McGill, as Michael Wozny (Faculty of Medicine and Health Sciences) and Valentin Nelea (Faculty of Dental Medicine and Oral Health Sciences) spearheaded the experimental approaches together with other team members and a visiting scholar.
Congratulations to these ACB graduate students on receiving funding!
Publication from ACB and McGill Undergraduates
A useful tool in protein research comes from the collaborative efforts of two bright McGill undergraduates, Jerry Gao and Maxwell Tong. Under the supervision of postdoctoral fellow Thibault Legal and Associate Professor Khanh Huy Bui, Jerry and Max developed the DomainFit program for the identification of protein domains in cryo-electron microscopy (cryo-EM) maps at intermediate resolutions.
New publication from the Bui Lab
Effect of α-tubulin acetylation on the doublet microtubule structure.Acetylation of α-tubulin at the lysine 40 residue (αK40) by αTAT1/MEC-17 acetyltransferase modulates microtubule properties and occurs in most eukaryotic cells. Previous literatures suggest that acetylated microtubules are more stable and damage resistant. αK40 acetylation is the only known microtubule luminal post-translational modification site.
New Publication by Postdoctoral Fellow Lia Paim
Cell division is a fundamental process for growth and repair in our bodies. It relies on the beautiful and complex machinery of the mitotic spindle to ensure the accurate distribution of genetic material. The spindle is made up of tiny structures called microtubules, which act like molecular cables to move chromosomes to the right places.
Graduate student Kalley Kho is first author in a new JCI publication
Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption