Marie-Astrid Lefebvre

Academic title(s): 

Assistant Professor 

MD, MSc, FRCPC 

Marie-Astrid Lefebvre
Contact Information
Address: 

Montreal Children’s Hospital
1001 Decarie Boulevard, Room 1954
Montreal, Quebec, H4A 3J1

Email address: 
marie-astrid.lefebvre.med [at] ssss.gouv.qc.ca
Division: 
Infectious Diseases
Area(s): 
Epidemiology
Quality improvement
Degree(s): 
  • Doctorem Medicinae et Chirurgiae Magistrum (MD CM), Faculty of Medicine, McGill University, Montreal, Quebec, August 2004-May 2008
  • Family Medicine Residency (partial), Hôpital Maisonneuve-Rosemont, Université de Montréal, Montreal, Quebec, July 2008-March 2009
  • Pediatrics Residency, Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts, United States, June 2009-June 2012
  • Pediatric Infectious Diseases Fellowship, Montreal Children’s Hospital, McGill University Health Centre, Montreal, Quebec, July 2012-August 2014
  • Infection Prevention and Control Fellowship, Mount Sinai Hospital, Toronto, Ontario, July 2015-June 2016
  • MSc in Quality Improvement & Patient Safety, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, June 2015-July 2016
Biography: 

Dr. Marie-Astrid Lefebvre graduated from Medical School at McGill, completed her Pediatrics Residency at the Floating Hospital for Children (Tufts University) in Boston and then returned to McGill for her Pediatric Infectious Diseases training, which she completed in 2014. Dr. Lefebvre then did a fellowship in Infection Prevention and Control at Mount Sinai Hospital in Toronto, along with a master’s degree in quality Improvement and Patient Safety. She started as a Pediatric Infectious Diseases consultant at the Montreal Children’s Hospital (MCH) in July 2016 and became the Medical Director of IPC in December 2016. Dr. Lefebvre is also in charge of the Antimicrobial Stewardship Program and participates in the Immunocompromised (HIV) clinic. She shares that she “chose the Department of Pediatrics at McGill as it felt like home to me, and I knew it would be a great place to grow both professionally and academically”.

Areas of expertise: 
  • Pediatric Infectious Diseases 
  • Infection Prevention and control 
  • Antimicrobial stewardship 
  • HIV 
  • Quality Improvement
Areas of interest: 
  • Epidemiology of healthcare-associated infections in the pediatric population 
  • Prevention of healthcare-associated infections (e.g., viral respiratory infections, central line-associated bloodstream infections), especially using quality improvement methods 
  • Antimicrobial stewardship  
  • Short- and long-term outcomes of HIV-exposed and HIV-infected children 
Selected publications: 
  • Lefebvre MA, Robinson JL, Winters N, Allen UD, Buteau C, Embree J, Gagneur A, Hamilton N, Hui C, Langley JM. Vaderkooi OG, Quach C. Validation of RSV infections in paediatric transplant recipients reported to a national surveillance program: a PICNIC study. JAMMI. 2017;2(1):16-22.
  • Rahmouni El Idrissi K, Isabel S, Carbonneau J, Lafond M, Quach C, Caya C, Fontela P, Beltempo M, Boivin G, Lefebvre MA, Papenburg J. Molecular and epidemiologic investigation of a rhinovirus outbreak in a neonatal intensive care unit. Infect Control Hosp Epidemiol. 2018;0:1-3.
  • Robinson JL, McAlpine A, Barton M, Balamohan A, Davies HD, Skar G, Lefebvre MA, et al. Duration of antibiotic therapy and timing of shunt reimplantation in pediatric CSF shunt infections: A retrospective multicenter case series. J Pediatric Infect Dis Soc. 2022;11(8):357-360.
  • McAlpine A, Robinson JL, Barton M, Balamohan A, Davies HD, Skar G, Lefebvre MA, et al; Paediatric Investigators Collaborative Network on Infections in Canada. Cerebrospinal fluid shunt infections: A multicenter pediatric study. Pediatr Infect Dis J. 2022;41(6):449-454.
  • Choi KB, Steele V, Conly J, Chow B, Comeau JL, Embree J, Lee BE, Lefebvre MA, et al. Cerebrospinal fluid shunt-associated surgical site infection with three-month versus twelve-month surveillance periods in Canadian hospitals. Infect Control Hosp Epidemiol. 2022;1-4.
Awards, honours, and fellowships: 
  • Distinction in Research Award, Floating Hospital for Children at Tufts Medical Center, Boston, MA, United States, 2012
  • The 2021 MCH Above and Beyond Special Award for recognition of extraordinary leadership during COVID-19 pandemic, Montreal Children’s Hospital, McGill University Health Centre, 2021
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