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As harmful as dehydration?

We are all familiar with the drawbacks of dehydration, but we rarely hear about the harmful effects of overhydration. It is known that excess fluid accumulation can lead to dangerously low sodium levels in the blood or hyponatremia – a life-threatening condition that can result in brain swelling. Similarly, more is known about the mechanisms in the body that detect and drive thirst while little is known about how the brain detects a state of overhydration.

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Published: 22 May 2018

New approach to global-warming projections could make regional estimates more precise

A new method for projecting how the temperature will respond to human impacts supports the outlook for substantial global warming throughout this century – but also indicates that, in many regions, warming patterns are likely to vary significantly from those estimated by widely used computer models.

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Published: 15 May 2018

Climate change = a much greater diversity of species + a need to rethink conservation paradigms

A team of researchers believe that Quebec’s protected areas are poised to become biodiversity refuges of continental importance. They used ecological niche modeling to calculate potential changes in the presence of 529 species in about 1/3 of the protected areas in southern Quebec almost all of which were under 50 km2 in size....

Published: 15 May 2018

Beyond Killing Tuberculosis

Historically, our view of host defense against infection was that we must eliminate pathogens to eradicate disease. However, this perspective has recently been challenged as scientists have taken a lesson from plant biologists about an ancient strategy involving the ability to “tolerate” rather than “resist” infection to maintain health. This concept, referred to as “disease tolerance”, provides an opportunity to develop new strategies that mitigate the consequences of infection.

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Published: 11 May 2018

How heart tissue combines mechanical strength and electrical reliability

The human heart can be viewed as both a mechanical and an electrical device – one that contracts and pumps billions of times over an average lifespan. How does it manage to achieve this feat without lapsing into dangerous irregularities?   New research by McGill University scientists finds that the answer lies in the particular geometry of the muscle fibres of the heart wall....
Published: 10 May 2018

Dr. Claudio Cuello elected as a Fellow of the British Academy of Medical Sciences

Dr. Claudio Cuello, Professor and inaugural Charles E....

Published: 10 May 2018

Hanadi Sleiman, C.J. Li awarded Killam Research Fellowships

McGill chemistry professors Hanadi Sleiman and Chao-Jun Li are among the six recipients of this year’s Killam Research Fellowships. The two-year fellowships, awarded to exceptional researchers working on groundbreaking projects of broad significance, are valued at $70,000 a year.   Prof....
Published: 8 May 2018

The effect of night shifts: gene expression fails to adapt to new sleep patterns

Have you ever considered that working night shifts may, in the long run, have an impact on your health? A team of researchers from the McGill University affiliated Douglas Mental Health University Institute (DMHUI) has discovered that genes regulating important biological processes are incapable of adapting to new sleeping and eating patterns and that most of them stay tuned to their daytime biological clock rhythms.

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Published: 7 May 2018

A new molecular target identified in depression

The discovery of a new mechanism involved in depression – and a way to target it with a drug as effective as classical antidepressants -- provides new understanding of this illness and could pave the way for treatments with fewer side effects.

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Published: 7 May 2018

Nine McGill experts named new Canada Research Chairs

By Meaghan Thurston

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Published: 3 May 2018

NEOMED Institute partners with McGill University to identify small molecule inhibitors of a novel oncology target: Cut-Like Homeobox 1 (CUX1)

The NEOMED Institute announced today that it has entered into a development collaboration with McGill University. Kemal Payza, Senior Project Director at NEOMED Institute will collaborate with Professor Alain Nepveu, Professor at the Goodman Cancer Research Centre and Departments of Oncology, Biochemistry and Medicine at McGill University, to discover new therapeutic small molecules to inhibit the protein target, Cut-Like Homeobox 1 (CUX1).

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Published: 3 May 2018

Early HIV treatment key to avoiding brain atrophy

New study underlines importance of early screening and antiretroviral therapy

While the human immunodeficiency virus (HIV) has largely dropped from news headlines since the 1990s, at the end of 2016 there were 36.7 million people living with the infection, and of those only 53 per cent had access to treatment. A new study underscores the neurological consequences of exposure to HIV without antiretroviral therapy.

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Published: 3 May 2018

Garvin Brown & Steffanie Diamond Brown boost public policy at McGill, endowing Chair in Democratic Studies

A $5-million gift from McGillians G. Garvin Brown IV, BA’91, and his wife Steffanie Diamond Brown, will make a major contribution to research and teaching at McGill’s Max Bell School of Public Policy by establishing an endowed Chair in Democratic Studies. The Chair will promote further scholarship and public outreach, encourage public discussion of key challenges facing the world’s democracies, and contribute to evidence-based policy decision-making.

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Published: 3 May 2018

Nurses’ care of young mothers leaves traces in babies’ DNA

Researchers have known for a couple of decades that early life adversity can affect the way that particular genes function through a process called epigenetics - a bit like a dimmer switch on a light, pushing gene activity up or down....
Published: 1 May 2018

Jozsef Kövecses awarded NSERC Synergy Award for Innovation

By Meaghan Thurston

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Published: 1 May 2018

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