Depression drugs linked to failure of dental implants
The researchers reached this conclusion by looking back over the records of dental implants done over a six-year period, between 2007 – 2013, in a clinic in Moncton, New Brunswick. Follow-ups took place with the patients between three and 67 months after the implant was done to see whether it had been successful.
Results of 916 dental implants done on 490 patients
| Number of patients | Number of implants | Successful implants | Implant failures | Implant failures as a percentage of total number of implants done |
Patients not taking SSRIs | 439 | 822 | 784 | 38 | 4.62 % |
Patients taking SSRIs | 51 | 94 | 84 | 10 | 10.64% |
“Unfortunately, because this study was based on data collected after the implants had been done rather than through interviews with incoming patients, it is impossible right now to determine the kind of SSRI dosage that could have this effect,” says Tamimi. “But what this study tells us is both that further work needs to be done in the field and that whether they are planning to have dental implants or hip or knee prostheses, SSRI users should consult their physicians and plan carefully to ensure that the surgical treatment is successful.”
The research was funded by the China Scholarship Council, Clifford Wong Fellowship, Canadian Institutes of Health Research, Institute of Musculoskeletal Health and Arthritis Bridge Funding, and Le Réseau de recherche en santé buccodentaire et osseuse.
To read the full text “Selective Serotonin Reuptake Inhibitors and the Risk of Osseointegrated Implant Failure, A Cohort Study” par X. Wu et al in the Journal of Dental Research
To contact the researcher directly: faleh.tamimi [at] mcgill.ca
McGill Media Relations contact: katherine.gombay [at] mcgill.ca
https://www.mcgill.ca/newsroom/
PHOTO: THINKSTOCK