46 - Stomach: Carcinoma

Osler pathology specimen in jar

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Rodin Number: 41
E Number: 121
Donor: Osler
Date: 1878
Size (H x W cm): 18 x 19

The specimen consists of the stomach with a small portion of lower esophagus (E). There is a large carcinoma (arrows) which has ulcerated through the gastric wall revealing the adjacent liver (L).

Osler pathology specimen in jar

Comment

The case was documented in the PDF icon MGR and as Osler's autopsy protocol (Case CCLXXXI )PDF icon Rodin Pathology. The patient was a 45 year-old woman who had a 5-6 month history of "well marked symptoms of C” (presumably cancer). The minimal inflammatory reaction on the surface of the liver (most of which has a smooth appearance) suggests that the large size of the gastric disruption may be related to the autopsy/specimen handling. However, Osler's autopsy protocol indicates the presence of "two quarts of turbid fluid" in the peritoneal cavity, suggesting that rupture and peritonitis had indeed occurred.

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