endocrine disrupting chemicals, perturbateurs endocriniens

Knowledge Transfer

Publications

Hardy, C. & Maguire, S., 2019. Organizations, Risk Translation, and an Ecology of Risks: The Discursive Construction of a Novel Risk, Academy of Management Journal, Published Online: 2 May 2019, https://doi.org/10.5465/amj.2017.0987

Yan, H. and Hales, B. F. 2019. Effects of Organophosphate Ester Flame Retardants on Endochondral Ossification in Ex Vivo Murine Limb Bud Cultures. Toxicological Sciences Apr 1 2019, 168(2):420-429.

Tian L, Goodyer CG, Zheng J, Bayen S. 2020. Thermal degradation of bisphenol A and bisphenol S in water and fish (cod and basa) fillets. Food Chem. 328:126999.

Tian L., Zheng J., Goodyer C, Bayen S. 2020. Non-targeted screening of plastic-related contaminants in food from Montreal, Canada. Food Chemistry. 316: 126942.

Yan, H. and Hales, B. F. 2020. Exposure to tert-Butylphenyl Diphenyl Phosphate, an Organophosphate Ester Flame Retardant and Plasticizer, Alters Hedgehog Signaling in Murine Limb Bud Cultures. Toxicol Sci. 2020 Sep 25:kfaa145. doi: 10.1093/toxsci/kfaa145.

Hales BF, Robaire B. 2020. Effects of brominated and organophosphate ester flame retardants on male reproduction. Andrology. 8(4):915-923. doi: 10.1111/andr.12789. Epub 2020 Apr 28.

Rajkumar A, Luu T, Beal MA, Barton-Maclaren TS, Robaire B, Hales 2021. BF. Elucidation of the Effects of Bisphenol A and Structural Analogs on Germ and Steroidogenic Cells Using Single Cell High-Content Imaging. Toxicol Sci. 180(2):224-238. doi: 10.1093/toxsci/kfab012.

Wang X, Hales BF, Robaire B. 2021. Effects of flame retardants on ovarian function. Reprod Toxicol. 102:10-23. doi: 10.1016/j.reprotox.2021.03.006. Epub 2021 Apr 2.

We also invite you to refer to related publications that served as a basis for this research project.
 

Presentations

INVITED

  • Hales BF. Current Endocrine Disrupting Chemicals Affect Reproductive Health: The Pathway Towards A Safer Tomorrow? MUHC Urology Research Seminar, Montreal QC, Jan 31, 2017.
  • Hales BF. The Future of Endocrine Disrupting Chemicals: From Regrettable Substitutions to Responsible Replacements. Society for the Study of Reproduction. Washington DC, Jul 13-16, 2017.
  • Hales BF. The Future of Endocrine Disrupting Chemicals: From Regrettable Substitution to Responsible Replacement? Interdisciplinary Environmental Toxicology Program Open House, University of Illinois Champaign, Champaign, IL, Nov 10, 2017.
  • Hales BF, Robaire B. The search for safe replacements for endocrine disrupting chemicals. 10th Congress of Toxicology in Developing Countries. Belgrade, Serbia, Apr 18-21, 2018.
  • Hales BF. From Legacy Flame Retardants to their Replacements: a Bumpy Road? Brominated Flame Retardants Workshop 2018. Niagara College, Niagara on the Lake Campus, ON, May 24-25, 2018.
  • Robaire B, Hales BF. An Approach to Responsible Replacements for Endocrine Disrupting Chemicals. Society for the Study of Reproduction. New Orleans, LA, Jul 10-13, 2018.
  • Hales BF. Effects of Flame Retardants on Testicular Function. XXV North American Testis Workshop. Chicago, IL, Apr 3-6, 2019.


OTHER
(*) indicates that the first author is/was a graduate student, post-doctoral fellow or resident

  • Maguire S, Hardy C. Constructing Nov­el Risks: The Case of Bisphenol A. 10th Annual Conference of the Society for Risk Analysis of Australia and New Zealand (SRA-ANZ). Melbourne, Australia, Nov 22, 2017.
  • *Yan H, Hales BF. The search for safe re­­placements for endocrine disrupting flame retardants. 51st Gene Families and Isozymes Conference. Kona, HI, Dec 3-8, 2017.
  • *Yan H, Hales BF. Exposure to flame retardants alters the expression of mas­ter regulators of chondrogenesis and osteogenesis in murine limb buds. Bromi­nated Flame Retardants Workshop 2018. Niagara College, Niagara on the Lake Campus, ON, May 24-25, 2018.
  • Maguire S, Hardy C. The discursive construction of novel risks: The case of bisphenol A. 13th International Conference on Organizational Discourse. London, UK, Jul 12, 2018.
  • *Yan H, Hales BF. The effects of two new generation flame retardants on markers of oxidative stress and cell cycle regulation during endochondral ossification in mouse limb buds. 50th Annual Symposium of Society of Toxicology of Canada. Toronto, ON, Dec 10-12, 2018.
  • *Wang X, Robaire B, Hales BF. Effects of organophosphate ester flame retardants on a human granulosa cell line. 50th Annual Symposium of Society of Toxicology of Canada. Toronto, ON, Dec 10-12, 2018.
  • *Tardif S, Robaire B, Delbes, G. Criblage de la toxicité et du potentiel perturbateur endocrinien de plastifiants et d’ignifugeants émergents. Colloque TOXEN. Montreal, QC. May 9, 2019. (Poster Presentation)
  • *Yan H, Hales BF. Transcriptomic changes in murine limb buds exposed to tert-butylphenyl diphenyl phosphate. 9th International Symposium on Flame Retardants. Montreal, QC. May 15-17, 2019. (Oral Presentation)
  • *Yan H, Hales BF. The biological processes affected in murine limb buds exposed to tert-butylphenyl diphenyl phosphate. 9th International Symposium on Flame Retardants. Montreal, QC. May 15-17, 2019 (Poster Presentation)
  • *Wang X, Hales BF, Robaire B. Effects of organophosphate esters on a human granulosa cell line. 9th International Symposium on Flame Retardants. Montreal, QC. May 15-17, 2019. (Poster Presentation)
  • *Rajkumar A, Hales BF, Robaire B. Mitochondrial bioenergetic effects of an environmentally- relevant organophosphate ester (OPE) mixture on liver cells. 9th International Symposium on Flame Retardants. Montreal, QC. May 15-17, 2019. (Poster Presentation)
  • *Furlong D, Goodyer C, Kubwabo C, Siddique S, Zhang G, Bayen S. Organophosphate esters and their metabolites in food and breast milk – is dietary exposure an important pathway for Canadians? 9th International Symposium on Flame Retardants. Montreal, QC. May 15-17, 2019 (Poster Presentation)
  • *Tardif S, Robaire B, Delbes, G. Criblage de la toxicité et du potentiel perturbateur endocrinien de plastifiants et d’ignifugeants émergents. Journée de recherche en toxicologie et pharmacologie de l'INRS. Laval, QC. May 22, 2019 (Poster Presentation)
  • *Tian L, Bayen S. Determination of 11 bisphenols and other plastic-related contaminants in food using HPLC-QTOF-MS. 102nd Canadian Chemistry Conference and Exhibition. Quebec, QC. Jun 4-7, 2019 (Poster Presentation)
  • *Tian L, Bayen S. Non-targeted analysis of plastic-related contaminants in food from Montreal using HPLC-QTOF-MS. 63rd International Conference on Analytical Sciences and Spectroscopy. Montreal, QC. Jun 25-28, 2019. (Oral Presentation)
  • *Furlong D, Goodyer CG, Kubwabo C, Siddique S, Zhang G, Bayen S. Organophosphate esters and their metabolites in food and breast milk - is dietary exposure an important pathway for Canadians? EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • *Iskandarani L, Robaire B, Hales BF. The effects of bisphenol A on limb development in a murine limb bud culture system. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • Fan X, Kubwabo C, Katuri GP, Caza A, Rasmussen PE. Analysis of 16 bisphenol analogues in Canadian indoor house dust by gas chromatography - tandem mass spectrometry. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • Siddique S, Zhang G, Kubwabo C. Analytical methods to quantify OPEs, PBDEs and DPS in food, milk and water supplies. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • *Papaluca A. Analysis of the policy and regulations related to endocrine disrupting chemicals and their replacements. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • *Singh M, Sorisky A, Atlas E. The effects of BPA and its analogues on adipocyte differentiation. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • *Struzina L, Aneck-Hahn N, Bayen S, Bornman R, Cherif Y, Heide K, Kubwabo C, Lashuk B, Misunis K, Pineda M, Shaikh B, Siddique S, Tian L, Yargeau V. Concentrations of phthalates, BPS, OPEs and PBDEs in drinking water. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • *Tardif S, Robaire B, Delbès G. Screening for the safety of emerging plasticizers and flame retardants. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • *Tian L, Zheng J, Chevrier J, Goodyer CG, Bayen S. Determination of several bisphenol A structural analogues in food from Canada and South Africa. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • *Wang X, Luu T, Hales BF, Robaire B. Effects of organophosphate ester flame retardants, plasticizers and bisphenols on KGN cells, a human granulosa cell line. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • *Yan H; Hales BF. Gene expression changes in mouse limb buds exposed to an emerging organophosphate ester flame retardant BPDP. EDCs Annual Meeting 2019, Montreal, QC. Oct 25, 2019 (Poster Presentation)
  • *Tian L, Goodyer C, Zheng J, Bayen S. Determination of bisphenol S and ten other bisphenol analogues in fresh fish from Canada. 9th International Symposium on Recent Advances in Food Analysis (RAFA 2019). Prague, Czech Republic. Nov 5-8, 2019 (Poster Presentation)
  • *Tian L, Goodyer C, Zheng J, Bayen S. Non-targeted analysis of the degradation of four plastic-related contaminants in food during thermal treatment. 9th International Symposium on Recent Advances in Food Analysis (RAFA 2019). Prague, Czech Republic. Nov 5-8, 2019 (Oral Presentation)
  • *Tardif S, Robaire B, Delbes G. Screening for the safety of emerging plasticizers and flame-retardants. 12th Annual Symposium of the Réseau Québécois en Reproduction. Québec, QC. Nov 5-6, 2019 (Poster Presentation)
  • *Wang X. Effects of environmentally-relevant mixtures of organophosphate ester (OPE) flame retardants on KGN cells, a human granulosa cell line. 12th Annual Symposium of the Réseau Québécois en Reproduction. Québec, QC. Nov 5-6, 2019 (Poster Presentation)
  • *Yan H. An environmentally relevant mixture of organophosphate ester flame retardants negatively impacts endochondral ossification. 12th Annual Symposium of the Réseau Québécois en Reproduction. Québec, QC. Nov 5-6, 2019 (Poster Presentation)
  • *Singh M, Sorisky A, Atlas E. The Effects of BPA and its Analogues on Aipocyte Differentiation. 51st Annual Symposium of the Society of Toxicology of Canada. Ottawa, ON. Dec 2-4, 2019 (Poster Presentation)
  • *Rajkumar A, Luu T, Hales BF, Robaire B. Studying the toxicological effects of Bis­phenol A replacements on the KGN human granulosa cell line – A BMD analyses approach. 51st Annual Symposium of the Society of Toxicology of Canada. Ottawa, ON. Dec 2-4, 2019 (Poster Presentation)
  • *Wang X. Effects of environmentally-relevant mixtures of organophosphate ester (OPE) flame retardants on KGN cells, a human granulosa cell line. 51st Annual Symposium of the Society of Toxicology of Canada. Ottawa, ON. Dec 2-4, 2019 (Poster Presentation)
  • *Yan H. An environmentally relevant mixture of organophosphate ester flame retardants negatively impacts endochondral ossification. 51st Annual Symposium of the Society of Toxicology of Canada. Ottawa, ON. Dec 2-4, 2019 (Poster Presentation)
  • *Katen A. Effects of an environmentally relevant mixture of organophosphate esters on testis function in rats. ASA 45th Annual Conference. Apr 25-28, 2020 (Poster Presentation)
  • *Katen A. Early life exposure of rats to organophosphate flame retardants found in Canadian house dust causes reduced sperm production and increased oxidative stress. 53rd SSR Annual Meeting. Jul 9-12, 2020 (Poster Presentation)
  • *Struzina L. Plasticizers, Bisphenols, and Flame Retardants in Drinking Water. EDCs Annual Meeting 2020 (Virtual Meeting). Nov 5-6, 2020 (Oral Presentation)
  • Bayen S. Food / Breat Milk Samples. EDCs Annual Meeting 2020 (Virtual Meeting). Nov 5-6, 2020 (Oral Presentation)
  • *Wang X. Effects of organophosphate ester (OPE) flame retardants on KGN, MA-10, C18-4 cells. EDCs Annual Meeting 2020 (Virtual Meeting). Nov 5-6, 2020 (Oral Presentation)
  • *Rajkumar A. Elucidation of the effects of alternative bisphenols and plasticizers on germ and steroidogenic cell targets using high-content imaging. EDCs Annual Meeting 2020 (Virtual Meeting). Nov 5-6, 2020 (Oral Presentation)
  • Wade M. Bisphenols - Effects on sterodogenesis. EDCs Annual Meeting 2020 (Virtual Meeting). Nov 5-6, 2020 (Oral Presentation)
  • Atlas E. In Vitro cell models. EDCs Annual Meeting 2020 (Virtual Meeting). Nov 5-6, 2020 (Oral Presentation)
  • Delbes G. Screening for toxicity and endocrine disruptor potential of emerging plasticizers and flame-retardants using rat fetal testis organ culture. EDCs Annual Meeting 2020 (Virtual Meeting). Nov 5-6, 2020 (Oral Presentation)
  • *Iskandarani L. The effects of bisphenols on endochondral ossification in murine limb bud cultures. EDCs Annual Meeting 2020 (Virtual Meeting). Nov 5-6, 2020 (Oral Presentation)
  • *Yan H. Exposure to tert-butylphenyl diphenyl phosphate alters Hedgehog signaling in mouse limb buds. EDCs Annual Meeting 2020 (Virtual Meeting). Nov 5-6, 2020 (Oral Presentation)
  • *Wang X. Effects of organophosphate ester flame retardants on KGN cells, a human granulosa cell line. 13th RQR Symposium. Nov 9-11, 2020 (Poster Presentation)
  • *Katen A. Effects of an environmentally relevant mixture of organophosphate esters on testis function and sperm capacitation in rats. 13th RQR Symposium. Nov 9-11, 2020 (Oral Presentation)
  • *Wang X. Effects of organophosphate ester flame retardants on KGN cells, a human granulosa cell line. The Society of Toxicology of Canada 52nd Annual Symposium. Nov 30-Dec 2, 2020 (Poster Presentation)
  • *Yu D. High content imaging analyses of the effects of an environmentally relevant organophosphate ester mixture in the HepG2 cell line . The Society of Toxicology of Canada 52nd Annual Symposium. Nov 30-Dec 2, 2020 (Poster Presentation)
  • *Li Z. Effects of an environmentally-relevant mixture of organophosphate esters on human adreno-carcinoma cells (H295R cells). The Society of Toxicology of Canada 52nd Annual Symposium. Nov 30-Dec 2, 2020 (Poster Presentation)
  • *Yu D. Analyses of the effects of an environmentally relevant organophosphate ester mixture in the HepG2 cell line using high content imaging.  Society of Toxicology Annual Meeting & ToxExpo. Virtural Event - March 2021 (Poster Presentation)
  • *Wang X. Benchmark Concentration (BMC) Analyses of the Effects of Organophosphate Esters (OPEs) on the Phenotype and Function of KGN Human Granulosa Cells. Society of Toxicology Annual Meeting & ToxExpo. Virtural Event - March 2021 (Poster Presentation)
  • *Struzina, L., Pineda, M., Yargeau, V, Chemicals of emerging concern in drinking water, Chemical Engineering Research Day, Montreal (virtual), March 30-31, 2021
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