Publications

 

2019

  1. Ilie, A., A. Y. L. Gao, et al. 2019. A potential gain-of-function variant of SLC9A6 leads to endosomal alkalinization and neuronal atrophy associated with Christianson Syndrome. Neurobiol Dis 121: 187-204.

  2. Lacroix, A., Vengut-Climent E., de Rochambeau, D., and Sleiman, H. F. 2019. Uptake and Fate of Fluorescently Labeled DNA Nanostructures in Cellular Environments: A Cautionary Tale. ACS Central Science Article ASAP DOI: 10.1021/acscentsci.9b00174

  3. Luu, L., G. D. Ciccotosto, et al. 2019. Amyloid Precursor Protein Dimerisation Reduces Neurite Outgrowth. Mol Neurobiol 56(1): 13-28.

 

2018

  1. Aguilar-Valles, A., N. Haji, et al. 2018. Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E. Nat Commun 9(1): 2459.
  2. Amador-Canizares, Y., A. Bernier, et al. 2018. miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5' end from the cellular pyrophosphatases, DOM3Z and DUSP11. Nucleic Acids Res 46(10): 5139-5158.
  3. Barnard, T. R., M. M. Rajah, et al. 2018. Contemporary Zika Virus Isolates Induce More dsRNA and Produce More Negative-Strand Intermediate in Human Astrocytoma Cells. Viruses 10(12).
  4. Brown, C.M. 2018. Career in Core Facility Management. Cold Spring Harbor Perspectives in Biology. 10:a032805: 1-12. 
  5. Chaaban, S., S. Jariwala, et al. 2018. The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth. Dev Cell 47(2): 191-204 e198.
  6. Cordeiro Matos, S., M. Zamfir, et al. 2018. Noradrenergic fiber sprouting and altered transduction in neuropathic prefrontal cortex. Brain Struct Funct 223(3): 1149-1164.
  7. Cramer, Z., J. Sadek, et al. 2018. eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways. Sci Rep 8(1): 8414
  8. El-Hassan, A. R., V. Leung, et al. 2018. Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2. Mamm Genome 29(3-4): 229-244.
  9. Findlay, S., J. Heath, et al. 2018. SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice. EMBO J 37(18).
  10. Giannakopoulou, N., N. Mendis, et al. 2018. The Virulence Effect of CpxRA in Citrobacter rodentium Is Independent of the Auxiliary Proteins NlpE and CpxP. Front Cell Infect Microbiol 8: 320.
  11. Goyette, M. A., S. Duhamel, et al. 2018. The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression. Cell Rep 23(5): 1476-1490.
  12. Hakimzadeh, A., M. Okshevsky, et al. 2018. Exposure to Freeze-Thaw Conditions Increases Virulence of Pseudomonas aeruginosa to Drosophila melanogaster. Environ Sci Technol 52(24): 14180-14186.
  13. Hall, D. T., T. Griss, et al. 2018. The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting. EMBO Mol Med 10(7).
  14. Hirukawa, A., H. W. Smith, et al. 2018. Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program. Nat Commun 9(1): 2547.
  15. Huang, J., D. Kim, et al. 2018. Most bicarbonate secretion by Calu-3 cells is mediated by CFTR and independent of pendrin. Physiol Rep 6(5).
  16. Hulea, L., S. P. Gravel, et al. 2018. Translational and HIF-1alpha-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. Cell Metab 28(6): 817-832 e818.
  17. Juzwik, C. A., S. Drake, et al. 2018. Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis. Sci Rep 8(1): 13437.
  18. Kim, M., J.P. Tang, and N.S. Moon. 2018. An alternatively spliced form affecting the Marked Box domain of Drosophila E2F1 is required for proper cell cycle regulation. PLoS genetics. 14:e1007204. PMID: 29420631
  19. Kim, S. Y., C. S. Yang, et al. 2018. ESRRA (estrogen-related receptor alpha) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense. Autophagy 14(1): 152-168.
  20. Knight, J. F., V. Y. C. Sung, et al. 2018. KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer. Cell Rep 22(12): 3191-3205.
  21. Kostenko, S., C. C. Heu, et al. 2018. c-Src regulates cargo transit via the Golgi in pancreatic acinar cells. Sci Rep 8(1): 11903.
  22. Lapointe, J. F., C. D. McCarthy, et al. 2018. Physiological evidence of integrin-antibody reactive proteins influencing the innate cellular immune responses of larval Galleria mellonella hemocytes. Insect Sci.
  23. Latifi, N., M. Asgari, H. Vali, and L. Mongeau. 2018. A tissue-mimetic nano-fibrillar hybrid injectable hydrogel for potential soft tissue engineering applications. Scientific reports. 8:1047. PMID: 29348423 
  24. Li, Y., G. Schang, et al. 2018. Conditional Deletion of FOXL2 and SMAD4 in Gonadotropes of Adult Mice Causes Isolated FSH Deficiency. Endocrinology 159(7): 2641-2655.
  25. Liu, J., J. D. S. Reggiani, et al. 2018. Tbr1 instructs laminar patterning of retinal ganglion cell dendrites. Nat Neurosci 21(5): 659-670.
  26. Maysinger D, Ji J, Moquin A, Hossain S, Hancock MA, Zhang I, Chang PKY, Rigby M, Anthonisen M, Grütter P, Breitner J, McKinney RA, Reimann S, Haag R, Multhaup G. 2018. Dendritic Polyglycerol Sulfates in the Prevention of Synaptic Loss and Mechanism of Action on Glia. ACS Chem Neurosci. 9(2):260-271. doi: 10.1021/acschemneuro.7b00301. PMID: 29078046
  27. Maysinger, D., A. Moquin, et al. 2018. Gold nanourchins and celastrol reorganize the nucleo- and cytoskeleton of glioblastoma cells. Nanoscale 10(4): 1716-1726.
  28. Ngan, E., Kiepas, A., Brown, C.M., Siegel, P.M. 2018. “Emerging roles for LPP in metastatic cancer progression.” J. Cell Comm. & Signal. Oct. 13. PMID: 29027626
  29. Okiyoneda, T., G. Veit, et al. 2018. Chaperone-Independent Peripheral Quality Control of CFTR by RFFL E3 Ligase. Dev Cell 44(6): 694-708 e697.
  30. Omer, A., D. Patel, et al. 2018. Stress granules counteract senescence by sequestration of PAI-1. EMBO Rep 19(5).
  31. Pandzic, E., A. Abu-Arish, et al. 2018. Velocity landscape correlation resolves multiple flowing protein populations from fluorescence image time series. Methods 140-141: 126-139.
  32. Rajakumar, R., S. Koch, et al. 2018. Social regulation of a rudimentary organ generates complex worker-caste systems in ants. Nature 562(7728): 574-577.
  33. Reed, S.J., Lafferty, C.K., Mendozza, J.A., Yang, A.K., Davidson, T.J., Grosenick L, Deisseroth K, Britt, J.P. 2018. Coordinated Reductions in Excitatory Input to the Nucleus Accumbens Underlie Food Consumption. Neuron.  pii: S0896-6273(18)30649-4 PMID : 30146308
  34. Sanz, R. L., G. B. Ferraro, et al. 2018. MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding. J Neurosci 38(3): 518-529.
  35. Singh, B. K., R. A. Sinha, et al. 2018. Thyroid hormone receptor and ERRalpha coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function. Sci Signal 11(536).
  36. Stochaj, U., D. C. Rodriguez Burbano, et al. 2018. The effects of lanthanide-doped upconverting nanoparticles on cancer cell biomarkers. Nanoscale 10(30): 14464-14471
  37. Stolarczyk, M., G. Veit, et al. 2018. Extracellular oxidation in cystic fibrosis airway epithelium causes enhanced EGFR/ADAM17 activity. Am J Physiol Lung Cell Mol Physiol 314(4): L555-L568.
  38. Tang, K., Boudreau, C.G., Brown, C.M.*, Khadra, A.* 2018. “Paxillin phosphorylation at serine 273 and its effects on Rac, Rho and adhesion dynamics.” PLOS Computational Biology. July 5, 2018: 1-29. PMID: 29975690
  39. Tavakolian, M., M. Okshevsky, et al. 2018. Developing Antibacterial Nanocrystalline Cellulose Using Natural Antibacterial Agents. ACS Appl Mater Interfaces 10(40): 33827-33838.
  40. Valiei, A., M. Okshevsky, et al. 2018. Anodized Aluminum with Nanoholes Impregnated with Quaternary Ammonium Compounds Can Kill Pathogenic Bacteria within Seconds of Contact. ACS Appl Mater Interfaces.
  41. Wong, F.H., A. AbuArish, E. Matthes, M.J. Turner, L.E. Greene, A. Cloutier, R. Robert, D.Y. Thomas, G. Cosa, A.M. Cantin, and J.W. Hanrahan. 2018. Cigarette smoke activates CFTR through ROS-stimulated cAMP signaling in human bronchial epithelial cells. American journal of physiology. Cell physiology. 314:C118-C134. PMID: 28978522
  42. Zakaria, C., P. Sean, et al. 2018. Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis. PLoS Pathog 14(8): e1007264.

 

2017

  1. Andersson, J. A., J. Sha, et al. 2017. Identification of New Virulence Factors and Vaccine Candidates for Yersinia pestis. Front Cell Infect Microbiol 7: 448.
  2. Cinti, A., V. Le Sage, M.P. Milev, F. Valiente-Echeverria, C. Crossie, M.J. Miron, N. Pante, M. Olivier, and A.J. Mouland. 2017. HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases. Scientific reports. 7:5515. PMID: 28710431
  3. Cruceanu, C., J.F. Schmouth, S.G. Torres-Platas, J.P. Lopez, A. Ambalavanan, E. Darcq, F. Gross, B. Breton, D. Spiegelman, D. Rochefort, P. Hince, J.M. Petite, J. Gauthier, R.G. Lafreniere, P.A. Dion, C.M. Greenwood, B.L. Kieffer, M. Alda, G. Turecki, and G.A. Rouleau. 2017. Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors. Molecular psychiatry. PMID: 29158579
  4. Dagenais, M., J. Dupaul-Chicoine, T. Douglas, C. Champagne, A. Morizot, and M. Saleh. 2017. The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis. Oncoimmunology. 6:e1287247. PMID: 28405519
  5. Deagle, R.C., T.L. Wee, and C.M. Brown. 2017. Reproducibility in light microscopy: Maintenance, standards and SOPs. The international journal of biochemistry & cell biology. 89:120-124. PMID: 28606390
  6. Dimitrov, V., M. Bouttier, G. Boukhaled, R. Salehi-Tabar, R.G. Avramescu, B. Memari, B. Hasaj, G.L. Lukacs, C.M. Krawczyk, and J.H. White. 2017. Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice. The Journal of biological chemistry. 292:20657-20668. PMID: 29061851
  7. El-Hassan, A.R., V. Leung, F. Kharfallah, M.C. Guyot, R. Allache, P. Gros, and Z. Kibar. 2017. Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2. Mammalian genome : official journal of the International Mammalian Genome Society. PMID: 29063958
  8. Gantois, I., A. Khoutorsky, J. Popic, A. Aguilar-Valles, E. Freemantle, R. Cao, V. Sharma, T. Pooters, A. Nagpal, A. Skalecka, V.T. Truong, S. Wiebe, I.A. Groves, S.M. Jafarnejad, C. Chapat, E.A. McCullagh, K. Gamache, K. Nader, J.C. Lacaille, C.G. Gkogkas, and N. Sonenberg. 2017. Metformin ameliorates core deficits in a mouse model of fragile X syndrome. Nature medicine. 23:674-677. PMID: 28504725
  9. Gonzalez-Morales, N., T.K. Holenka, and F. Schock. 2017. Filamin actin-binding and titin-binding fulfill distinct functions in Z-disc cohesion. PLoS genetics. 13:e1006880. PMID: 28732005
  10. Kaplan, A., B. Morquette, A. Kroner, S. Leong, C. Madwar, R. Sanz, S.L. Banerjee, J. Antel, N. Bisson, S. David, and A.E. Fournier. 2017. Small-Molecule Stabilization of 14-3-3 Protein-Protein Interactions Stimulates Axon Regeneration. Neuron. 93:1082-1093 e1085. PMID: 28279353
  11. Landry, M.J., M.B. Applegate, O.S. Bushuyev, F.G. Omenetto, D.L. Kaplan, M. Cronin-Golomb, and C.J. Barrett. 2017. Photo-induced structural modification of silk gels containing azobenzene side groups. Soft matter. 13:2903-2906. [PDF]
  12. Leventis, R., and J.R. Silvius. 2017. Incorporation of Artificial Lipid-Anchored Proteins into Cultured Mammalian Cells. Methods in molecular biology. 1609:241-253. PMID: 28660587
  13. Li Fraine, S., A. Patel, et al. 2017. Dynamic regulation of TREK1 gating by Polycystin 2 via a Filamin A-mediated cytoskeletal Mechanism. Sci Rep 7(1): 17403.
  14. Liebsch, F., M.R.P. Aurousseau, T. Bethge, H. McGuire, S. Scolari, A. Herrmann, R. Blunck, D. Bowie, and G. Multhaup. 2017. Full-length cellular beta-secretase has a trimeric subunit stoichiometry, and its sulfur-rich transmembrane interaction site modulates cytosolic copper compartmentalization. The Journal of biological chemistry. 292:13258-13270. PMID: 28637867
  15. Li-Jessen, N. Y. K., M. Powell, et al. 2017. Cellular source and proinflammatory roles of high-mobility group box 1 in surgically injured rat vocal folds. Laryngoscope 127(6): E193-E200.
  16. Ma, J.F., B.J. Sanchez, D.T. Hall, A.K. Tremblay, S. Di Marco, and I.E. Gallouzi. 2017. STAT3 promotes IFNgamma/TNFalpha-induced muscle wasting in an NF-kappaB-dependent and IL-6-independent manner. EMBO molecular medicine. 9:622-637. PMID: 28264935
  17. Morita, M., J. Prudent, et al. 2017. mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1. Mol Cell 67(6): 922-935 e925.
  18. Moujaber, O., H. Mahboubi, M. Kodiha, M. Bouttier, K. Bednarz, R. Bakshi, J. White, L. Larose, I. Colmegna, and U. Stochaj. 2017. Dissecting the molecular mechanisms that impair stress granule formation in aging cells. Biochim Biophys Acta. 1864:475-486. PMID: 27965113
  19. Mubaid, F., Brown, C.M. 2017. “Less is More: Longer exposure times with low light intensity is less photo-toxic”. Microscopy Today, November Issue, 1-8. [PDF]
  20. Ngan, E., K. Stoletov, H.W. Smith, J. Common, W.J. Muller, J.D. Lewis, and P.M. Siegel. 2017. LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis. Nature communications. 8:15059. PMID: 28436416
  21. Sanz, R.L., G.B. Ferraro, M.P. Girouard, and A.E. Fournier. 2017. Ectodomain shedding of Limbic System-Associated Membrane Protein (LSAMP) by ADAM Metallopeptidases promotes neurite outgrowth in DRG neurons. Scientific reports. 7:7961. [PDF]
  22. Sanz, R.L., G.B. Ferraro, J. Kacervosky, C. Salesse, E. Gowing, L. Hua, I. Rambaldi, F. Beaubien, K. Holmbeck, J.F. Cloutier, M. Levesque, K. Murai, and A.E. Fournier. 2017. MT3-MMP promotes excitatory synapse formation by promoting Nogo-66 receptor ectodomain shedding. The Journal of neuroscience : the official journal of the Society for Neuroscience. PMID: 29196321
  23. Savage, P., A. Blanchet-Cohen, et al. 2017. A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer. Cell Rep 21(5): 1140-1149.
  24. Shafer, M.E.R., A.H.T. Nguyen, M. Tremblay, S. Viala, M. Béland, N.R. Bertos, M. Park, and M. Bouchard. 2017. Lineage Specification from Prostate Progenitor Cells Requires Gata3-Dependent Mitotic Spindle Orientation. Stem Cell Reports. 8:1018-1031. PMID: 28285879
  25. Sharma, R., M. E. R. Shafer, et al. 2017. Bmp signaling maintains a mesoderm progenitor cell state in the mouse tailbud. Development 144(16): 2982-2993.
  26. Simond, A. M., T. Rao, et al. 2017. ErbB2-positive mammary tumors can escape PI3K-p110alpha loss through downregulation of the Pten tumor suppressor. Oncogene 36(43): 6059-6066.
  27. Stewart, K., Y. C. Tang, et al. 2017. Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis. Proc Natl Acad Sci U S A 114(43): E9016-E9025.
  28. Thomassin, J.L., J.M. Leclerc, N. Giannakopoulou, L. Zhu, K. Salmon, A. Portt, F. Daigle, H. Le Moual, and S. Gruenheid. 2017. Systematic Analysis of Two-Component Systems in Citrobacter rodentium Reveals Positive and Negative Roles in Virulence. Infection and immunity. 85. PMID: 27872242
  29. Tung, B., B. Schade, et al. 2017. beta-Catenin haploinsufficiency promotes mammary tumorigenesis in an ErbB2-positive basal breast cancer model. Proc Natl Acad Sci U S A 114(5): E707-E716.
  30. Uetani, N., S. Hardy, S.P. Gravel, S. Kiessling, A. Pietrobon, N.N. Wong, V. Chenard, N. Cermakian, J. St-Pierre, and M.L. Tremblay. 2017. PRL2 links magnesium flux and sex-dependent circadian metabolic rhythms. JCI insight. 2. PMID: 28679948
  31. Valanparambil, R.M., M. Tam, A. Jardim, T.G. Geary, and M.M. Stevenson. 2017. Primary Heligmosomoides polygyrus bakeri infection induces myeloid-derived suppressor cells that suppress CD4(+) Th2 responses and promote chronic infection. Mucosal immunology. 10:238-249. PMID: 27072608

 

2016

  1. Beaubien, F., R. Raja, T.E. Kennedy, A.E. Fournier, and J.F. Cloutier. 2016. Slitrk1 is localized to excitatory synapses and promotes their development. Scientific reports. 6:27343. PMID: 27273464
  2. Boudreau, C., T.L. Wee, Y.R. Duh, M.P. Couto, K.H. Ardakani, and C.M. Brown. 2016. Excitation Light Dose Engineering to Reduce Photo-bleaching and Photo-toxicity. Scientific reports. 6:30892. [PDF]
  3. Boulay, P.L., L. Mitchell, J. Turpin, J.E. Huot-Marchand, C. Lavoie, V. Sanguin-Gendreau, L. Jones, S. Mitra, J.M. Livingstone, S. Campbell, M. Hallett, G.B. Mills, M. Park, L. Chodosh, D. Strathdee, J.C. Norman, and W.J. Muller. 2016. Rab11-FIP1C Is a Critical Negative Regulator in ErbB2-Mediated Mammary Tumor Progression. Cancer Res. 76:2662-2674. PMID: 26933086
  4. Bouttier, M., D. Laperriere, B. Memari, J. Mangiapane, A. Fiore, E. Mitchell, M. Verway, M.A. Behr, R. Sladek, L.B. Barreiro, S. Mader, and J.H. White. 2016. Alu repeats as transcriptional regulatory platforms in macrophage responses to M. tuberculosis infection. Nucleic acids research. 44:10571-10587. PMID: 27604870
  5. Bradley-Gill, M.R., M. Kim, D. Feingold, C. Yergeau, J. Houde, and N.S. Moon. 2016. Alternate transcripts of the Drosophila "activator" E2F are necessary for maintenance of cell cycle exit during development. Developmental biology. 411:195-206. PMID: 26859702
  6. Bujold, K.E., J.C. Hsu, and H.F. Sleiman. 2016. Optimized DNA "Nanosuitcases" for Encapsulation and Conditional Release of siRNA. Journal of the American Chemical Society[PDF]
  7. Cyr-Depauw, C., J.J. Northey, S. Tabaries, M.G. Annis, Z. Dong, S. Cory, M. Hallett, J.P. Rennhack, E.R. Andrechek, and P.M. Siegel. 2016. Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion. Molecular and cellular biology. 36:1509-1525. PMID: 26976638
  8. Dagenais, M., J. Dupaul-Chicoine, C. Champagne, A. Skeldon, A. Morizot, and M. Saleh. 2016. A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways. Mucosal immunology. 9:146-158. PMID: 26037070
  9. Deblois, G., H.W. Smith, I.S. Tam, S.P. Gravel, M. Caron, P. Savage, D.P. Labbe, L.R. Begin, M.L. Tremblay, M. Park, G. Bourque, J. St-Pierre, W.J. Muller, and V. Giguere. 2016. ERRalpha mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nature communications. 7:12156. PMID: 27402251
  10. Dehghani, M., and P. Lasko. 2016. C-terminal residues specific to Vasa among DEAD-box helicases are required for its functions in piRNA biogenesis and embryonic patterning. Development genes and evolution. 226:401-412. PMID: 27572922
  11. Do Carmo, S., C.E. Hanzel, M.L. Jacobs, Z. Machnes, M.F. Iulita, J. Yang, L. Yu, A. Ducatenzeiler, M. Danik, L.S. Breuillaud, D.A. Bennett, M. Szyf, and A.C. Cuello. 2016. Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model. Scientific reports. 6:34051. PMID: 27681803
  12. Fregoso Lomas, M., S. De Vito, J.F. Boisclair Lachance, J. Houde, and L.A. Nilson. 2016. Determination of EGFR Signaling Output by Opposing Gradients of BMP and JAK/STAT Activity. Current biology : CB. 26:2572-2582. PMID: 27593379
  13. Girouard, M.P., M. Pool, R. Alchini, I. Rambaldi, and A.E. Fournier. 2016. RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress. PloS one. 11:e0168641. PMID: 27992599
  14. Goulet-Hanssens, A., M.H. Magdesian, G.M. Lopez-Ayon, P. Grutter, and C.J. Barrett. 2016. Reversing adhesion with light: a general method for functionalized bead release from cells. Biomater Sci. 4:1193-1196. PMID: 27165466
  15. Heileman, K.L., J. Daoud, and M. Tabrizian. 2016. Elaboration of a finite element model of pancreatic islet dielectric response to gap junction expression and insulin release. Colloids and surfaces. B, Biointerfaces. 148:474-480. PMID: 27665380
  16. Heris, H.K., J. Daoud, S. Sheibani, H. Vali, M. Tabrizian, and L. Mongeau. 2016. Investigation of the Viability, Adhesion, and Migration of Human Fibroblasts in a Hyaluronic Acid/Gelatin Microgel-Reinforced Composite Hydrogel for Vocal Fold Tissue Regeneration. Adv Healthc Mater. 5:255-265. PMID: 26501384
  17. Ilie, A., A.Y. Gao, J. Reid, A. Boucher, C. McEwan, H. Barriere, G.L. Lukacs, R.A. McKinney, and J. Orlowski. 2016. A Christianson syndrome-linked deletion mutation ((287)ES(288)) in SLC9A6 disrupts recycling endosomal function and elicits neurodegeneration and cell death. Mol Neurodegener. 11:63. PMID: 27590723
  18. Jia, B., T.L. Wee, C.G. Boudreau, D.J. Berard, A. Mallik, D. Juncker, C.M. Brown, and S.R. Leslie. 2016. Parallelized cytoindentation using convex micropatterned surfaces. BioTechniques. 61:73-82. PMID: 27528072
  19. Kaur, S., Y. Coulombe, Z.M. Ramdzan, L. Leduy, J.Y. Masson, and A. Nepveu. 2016. Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair. The Journal of biological chemistry. 291:22769-22780. PMID: 27590341
  20. Khoutorsky, A., R.E. Sorge, M. Prager-Khoutorsky, S.A. Pawlowski, G. Longo, S.M. Jafarnejad, S. Tahmasebi, L.J. Martin, M.H. Pitcher, C.G. Gkogkas, R. Sharif-Naeini, A. Ribeiro-da-Silva, C.W. Bourque, F. Cervero, J.S. Mogil, and N. Sonenberg. 2016. eIF2alpha phosphorylation controls thermal nociception. Proc Natl Acad Sci U S A. 113:11949-11954. PMID: 27698114
  21. Klein, H., A. Abu-Arish, N.T. Trinh, Y. Luo, P.W. Wiseman, J.W. Hanrahan, E. Brochiero, and R. Sauve. 2016. Investigating CFTR and KCa3.1 Protein/Protein Interactions. PloS one. 11:e0153665. PMID: 27092946
  22. Konokhova, Y., S. Spendiff, R.T. Jagoe, S. Aare, S. Kapchinsky, N.J. MacMillan, P. Rozakis, M. Picard, M. Aubertin-Leheudre, C.H. Pion, J. Bourbeau, R.T. Hepple, and T. Taivassalo. 2016. Failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers of chronic obstructive pulmonary disease locomotor muscle. Skelet Muscle. 6:10. PMID: 26893822
  23. Kowanda, M., J. Bergalet, M. Wieczorek, G. Brouhard, E. Lecuyer, and P. Lasko. 2016. Loss of function of the Drosophila Ninein-related centrosomal protein Bsg25D causes mitotic defects and impairs embryonic development. Biology open. 5:1040-1051. PMID: 27422905
  24. Latifi, N., H.K. Heris, S.L. Thomson, R. Taher, S. Kazemirad, S. Sheibani, N.Y. Li-Jessen, H. Vali, and L. Mongeau. 2016. A Flow Perfusion Bioreactor System for Vocal Fold Tissue Engineering Applications. Tissue Eng Part C Methods. 22:823-838. PMID: 27537192
  25. Lawrence, E.J., E. Boucher, and C.A. Mandato. 2016. Mitochondria-cytoskeleton associations in mammalian cytokinesis. Cell division. 11:3. PMID: 27030796 
  26. Leung, V., A. Iliescu, C. Jolicoeur, M. Gravel, S. Apuzzo, E. Torban, M. Cayouette, and P. Gros. 2016. The planar cell polarity protein Vangl2 is required for retinal axon guidance. Developmental neurobiology. 76:150-165. PMID: 25990804
  27. Li, J., A.L. Luco, B. Ochietti, I. Fadhil, A. Camirand, T.A. Reinhardt, R. St-Arnaud, W. Muller, and R. Kremer. 2016. Tumoral Vitamin D Synthesis by CYP27B1 1-alpha-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-kappaB Modulation. Endocrinology. 157:2204-2216. PMID: 27119753
  28. Liao, K.A., N. Gonzalez-Morales, and F. Schock. 2016. Zasp52, a Core Z-disc Protein in Drosophila Indirect Flight Muscles, Interacts with alpha-Actinin via an Extended PDZ Domain. PLoS genetics. 12:e1006400. PMID: 27783625
  29. Ling, E.J., V. Uong, J.S. Renault-Crispo, A.M. Kietzig, and P. Servio. 2016. Reducing Ice Adhesion on Nonsmooth Metallic Surfaces: Wettability and Topography Effects. ACS Appl Mater Interfaces. 8:8789-8800. PMID: 26953827 
  30. Madwar, C., G. Gopalakrishnan, and R.B. Lennox. 2016. Lipid Microdomains in Synapse Formation. ACS Chem Neurosci. 7:833-841. PMID: 27070205
  31. Mahboubi, H., A.E. Koromilas, and U. Stochaj. 2016. AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization. Mol Pharmacol. 90:460-468. PMID: 27430620
  32. Paredes, J. C., J. K. Herren, et al. 2016. The Role of Lipid Competition for Endosymbiont-Mediated Protection against Parasitoid Wasps in Drosophila. MBio 7(4).
  33. Penney, J., K. Tsurudome, E.H. Liao, G. Kauwe, L. Gray, A. Yanagiya, R.C. M, N. Sonenberg, and A.P. Haghighi. 2016. LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction. Nature communications. 7:12188. PMID: 27432119
  34. Power, G.A., F.C. Minozzo, S. Spendiff, M.E. Filion, Y. Konokhova, M.F. Purves-Smith, C. Pion, M. Aubertin-Leheudre, J.A. Morais, W. Herzog, R.T. Hepple, T. Taivassalo, and D.E. Rassier. 2016. Reduction in single muscle fiber rate of force development with aging is not attenuated in world class older masters athletes. American journal of physiology. Cell physiology. 310:C318-327. PMID: 26632598
  35. Qi, X., J. Sun, and H. Zheng. 2016. A GTPase-Dependent Fine ER Is Required for Localized Secretion in Polarized Growth of Root Hairs1. Plant Physiol. 171:1996-2007. PMID: 27231102
  36. Rajadurai, C.V., S. Havrylov, P.P. Coelho, C.D. Ratcliffe, K. Zaoui, B.H. Huang, A. Monast, N. Chughtai, V. Sangwan, F.B. Gertler, P.M. Siegel, and M. Park. 2016. 5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion. The Journal of cell biology. 214:719-734. PMID: 27597754
  37. Rappaz, B., K. Lai Wing Sun, J.P. Correia, P.W. Wiseman, and T.E. Kennedy. 2016. FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth Cones. PloS one. 11:e0159405. PMID: 27482713
  38. Ratcliffe, C.D., P. Sahgal, C.A. Parachoniak, J. Ivaska, and M. Park. 2016. Regulation of Cell Migration and beta1 Integrin Trafficking by the Endosomal Adaptor GGA3. Traffic. 17:670-688. PMID: 26935970
  39. Roohnikan, M., V. Toader, A. Rey, and L. Reven. 2016. Hydrogen-Bonded Liquid Crystal Nanocomposites. Langmuir. 32:8442-8450. [PDF]
  40. Rouger, V., R. Alchini, A. Kazarine, A.A. Gopal, M.P. Girouard, A.E. Fournier, and P.W. Wiseman. 2016. Low-cost multimodal light sheet microscopy for optically cleared tissues and living specimens. J Biomed Opt. 21:126008. PMID: 27999866
  41. Singh, S., M. Verma, M. Malhotra, S. Prakash, and T.D. Singh. 2016. Cytotoxicity of alkaloids isolated from Argemone mexicana on SW480 human colon cancer cell line. Pharmaceutical biology. 54:740-745. PMID: 26439487
  42. Skeldon, A.M., A. Morizot, T. Douglas, N. Santoro, R. Kursawe, J. Kozlitina, S. Caprio, W.Z. Mehal, and M. Saleh. 2016. Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance. Journal of immunology. 196:437-447. PMID: 26582949
  43. Sleno, R., D. Petrin, D. Devost, E. Goupil, A. Zhang, and T.E. Hebert. 2016. Designing BRET-based conformational biosensors for G protein-coupled receptors. Methods. 92:11-18. PMID: 25962643
  44. Spendiff, S., M. Vuda, G. Gouspillou, S. Aare, A. Perez, J.A. Morais, R.T. Jagoe, M.E. Filion, R. Glicksman, S. Kapchinsky, N.J. MacMillan, C.H. Pion, M. Aubertin-Leheudre, S. Hettwer, J.A. Correa, T. Taivassalo, and R.T. Hepple. 2016. Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J Physiol. 594:7361-7379. PMID: 27619626
  45. Stewart, K., Y. Gaitan, M.E. Shafer, L. Aoudjit, D. Hu, R. Sharma, M. Tremblay, H. Ishii, M. Marcotte, D. Stanga, Y.C. Tang, S.K. Boualia, A.H. Nguyen, T. Takano, N. Lamarche-Vane, S. Vidal, and M. Bouchard. 2016. A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects. PLoS genetics. 12:e1005785. PMID: 26859289
  46. Tanvir Ahmmed, K.M., and A.M. Kietzig. 2016. Drag reduction on laser-patterned hierarchical superhydrophobic surfaces. Soft matter. 12:4912-4922. [PDF]
  47. Tiner, B. L., J. Sha, et al. 2016. Immunisation of two rodent species with new live-attenuated mutants of Yersinia pestis CO92 induces protective long-term humoral- and cell-mediated immunity against pneumonic plague. NPJ Vaccines 1: 16020.
  48. Turpin, J., C. Ling, E.J. Crosby, Z.C. Hartman, A.M. Simond, L.A. Chodosh, J.P. Rennhack, E.R. Andrechek, J. Ozcelik, M. Hallett, G.B. Mills, R.D. Cardiff, J.W. Gray, O.L. Griffith, and W.J. Muller. 2016. The ErbB2DeltaEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment. Oncogene. 35:6053-6064. PMID: 27157621
  49. Urbanska, A.M., J. Bhathena, S. Cherif, and S. Prakash. 2016. Orally delivered microencapsulated probiotic formulation favorably impacts polyp formation in APC (Min/+) model of intestinal carcinogenesis. Artificial cells, nanomedicine, and biotechnology. 44:1-11. PMID: 25060720
  50. Verbich, D., Becker, D., Vlachos, A., Mundel, P., Deller, T., & McKinney, R. A. 2016. Rewiring neuronal microcircuits of the brain via spine head protrusions-a role for synaptopodin and intracellular calcium stores. Acta Neuropathologica Communications4, 38. PMID: 27102112
  51. Vijftigschild, L.A., G. Berkers, J.F. Dekkers, D.D. Zomer-van Ommen, E. Matthes, E. Kruisselbrink, A. Vonk, C.E. Hensen, S. Heida-Michel, M. Geerdink, H.M. Janssens, E.A. van de Graaf, I. Bronsveld, K.M. de Winter-de Groot, C.J. Majoor, H.G. Heijerman, H.R. de Jonge, J.W. Hanrahan, C.K. van der Ent, and J.M. Beekman. 2016. beta2-Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis. The European respiratory journal. 48:768-779. PMID: 27471203
  52. Vincent, K., V.M. Cornea, Y.J. Jong, A. Laferriere, N. Kumar, A. Mickeviciute, J.S. Fung, P. Bandegi, A. Ribeiro-da-Silva, K.L. O'Malley, and T.J. Coderre. 2016. Intracellular mGluR5 plays a critical role in neuropathic pain. Nature communications. 7:10604. PMID: 26837579
  53. Wieczorek, M., J. Tcherkezian, C. Bernier, A.E. Prota, S. Chaaban, Y. Rolland, C. Godbout, M.A. Hancock, J.C. Arezzo, O. Ocal, C. Rocha, N. Olieric, A. Hall, H. Ding, A. Bramoulle, M.G. Annis, G. Zogopoulos, P.G. Harran, T.M. Wilkie, R.A. Brekken, P.M. Siegel, M.O. Steinmetz, G.C. Shore, G.J. Brouhard, and A. Roulston. 2016. The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity. Science translational medicine. 8:365ra159. PMID: 27856798
  54. Yan, M., E. Audet-Walsh, S. Manteghi, C.R. Dufour, B. Walker, M. Baba, J. St-Pierre, V. Giguere, and A. Pause. 2016. Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1alpha/ERRalpha. Genes & development. 30:1034-1046. PMID: 27151976

 

2015

  1. Abu-Arish, A., E. Pandzic, J. Goepp, E. Matthes, J.W. Hanrahan, and P.W. Wiseman. 2015. Cholesterol modulates CFTR confinement in the plasma membrane of primary epithelial cells. Biophysical journal. 109:85-94. PMID: 26153705
  2. Accardi, M. V., P. M. Brown, et al. 2015. alpha6-Containing GABAA Receptors Are the Principal Mediators of Inhibitory Synapse Strengthening by Insulin in Cerebellar Granule Cells. J Neurosci 35(26): 9676-9688.
  3. Barucker,B., Bittner,H.J., Chang, P.K.Y., Cameron,S., Hancock,M.A., Harmeier,A., Shaw,H., Charron,F.M., Gensler,M, Dembny,P, Zhuang, Schmitz,D.,   Rabe,J.P,  Rao,Y., Lurz,R., Hildebrand,P.W., McKinney,R.A. and Multhaup,G. 2015. Aβ42-oligomer Interacting Peptide (AIP) neutralizes toxic amyloid-β42 species and protects synaptic structure and function. Sci. Rep. 2015 Oct 29, 5: 5:15410 PMID: 26510576
  4. Brown, C.M., A. Reilly, and R.W. Cole. 2015. A Quantitative Measure of Field Illumination. Journal of biomolecular techniques : JBT. 26:37-44. PMID: 25802488
  5. Chang, P. K-Y, Khatchadourian, A., McKinney, R.A.# and Maysinger, D. # (#Joint Senior). 2015. Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology J Neuroinflammation Dec;12(1):244. doi: 10.1186/s12974-015-0244-5. PMID: 25889069
  6. Dehghani, M., and P. Lasko. 2015. In vivo mapping of the functional regions of the DEAD-box helicase Vasa. Biology open. 4:450-462. PMID: 25795910
  7. Ghosh, S., and P. Lasko. 2015. Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis. PloS one. 10:e0122519. PMID: 25849588
  8. Jonkman, J., and C.M. Brown. 2015. Any Way You Slice It-A Comparison of Confocal Microscopy Techniques. Journal of biomolecular techniques : JBT. 26:54-65. PMID: 25802490
  9. Kharitidi, D., P.M. Apaja, S. Manteghi, K. Suzuki, E. Malitskaya, A. Roldan, M.C. Gingras, J. Takagi, G.L. Lukacs, and A. Pause. 2015. Interplay of Endosomal pH and Ligand Occupancy in Integrin alpha5beta1 Ubiquitination, Endocytic Sorting, and Cell Migration. Cell reports. 13:599-609. PMID: 26456826
  10. Krawchuk, D., S. Anani, N. Honma-Yamanaka, S. Polito, M. Shafik, and Y. Yamanaka. 2015. Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo. Journal of cell science. 128:1011-1022. PMID: 25588837
  11. Lariviere, R., R. Gaudet, et al. 2015. Sacs knockout mice present pathophysiological defects underlying autosomal recessive spastic ataxia of Charlevoix-Saguenay. Hum Mol Genet 24(3): 727-739.
  12. Liu, N., and P. Lasko. 2015. Analysis of RNA Interference Lines Identifies New Functions of Maternally-Expressed Genes Involved in Embryonic Patterning in Drosophila melanogaster. G3. 5:1025-1034. PMID: 25834215
  13. Maysinger, D., Groger, D., Lake, A., Licha, L., Weinhart, M., Chang, P.K., Mulvey, R., Hagg, R. and McKinney, R.A. 2015. Dendritic polyglycerol sulfate inhibits microglial activation and reduces hippocampal CA1 dendritic spine morphology deficits. Biomacromolecues2015 Sept 14:16(9):3073-3082. PMID: 26218295
  14. Morquette, B., P. Morquette, et al. 2015. REDD2-mediated inhibition of mTOR promotes dendrite retraction induced by axonal injury. Cell Death Differ 22(4): 612-625.
  15. Olsson, A.L., M.R. Mitzel, and N. Tufenkji. 2015. QCM-D for non-destructive real-time assessment of Pseudomonas aeruginosa biofilm attachment to the substratum during biofilm growth. Colloids and surfaces. B, Biointerfaces. 136:928-934. PMID: 26551870
  16. Petitjean, H., S.A. Pawlowski, S.L. Fraine, B. Sharif, D. Hamad, T. Fatima, J. Berg, C.M. Brown, L.Y. Jan, A. Ribeiro-da-Silva, J.M. Braz, A.I. Basbaum, and R. Sharif-Naeini. 2015. Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury. Cell reports. 13:1246-1257. PMID: 26527000
  17. Robellet, X., Y. Thattikota, F. Wang, T.L. Wee, M. Pascariu, S. Shankar, E. Bonneil, C.M. Brown, and D. D'Amours. 2015. A high-sensitivity phospho-switch triggered by Cdk1 governs chromosome morphogenesis during cell division. Genes & development. 29:426-439. PMID: 25691469
  18. Sanz, R., G.B. Ferraro, and A.E. Fournier. 2015. IgLON cell adhesion molecules are shed from the cell surface of cortical neurons to promote neuronal growth. The Journal of biological chemistry. 290:4330-4342. PMID:25538237
  19. Shao, W., A. Paul, L. Rodes, and S. Prakash. 2015. A New Carbon Nanotube-Based Breast Cancer Drug Delivery System: Preparation and In Vitro Analysis Using Paclitaxel. Cell biochemistry and biophysics. 71:1405-1414. PMID:27101155
  20. Wieczorek, M., S. Bechstedt, S. Chaaban, and G.J. Brouhard. 2015. Microtubule-associated proteins control the kinetics of microtubule nucleation. Nature cell biology. 17:907-916. PMID: 26098575

 

2014

  1. Anani, S., S. Bhat, N. Honma-Yamanaka, D. Krawchuk, and Y. Yamanaka. 2014. Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo. Development. 141:2813-2824. PMID: 24948601
  2. Bagci, H., M. Laurin, J. Huber, W.J. Muller, and J.F. Cote. 2014. Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling. Cell Death Dis. 5:e1375. PMID: 25118935
  3. Biard, R., D. Kaufman, and C.M. Brown. 2014. Mercury Free Microscpy: An Opportunity for Core Facility Directors. J. Biomol Tech. July:In Press. PMID: 24982596
  4. Brandao, H.B., H. Sangji, E. Pandzic, S. Bechstedt, G.J. Brouhard, and P.W. Wiseman. 2014. Measuring ligand-receptor binding kinetics and dynamics using k-space image correlation spectroscopy. Methods. 66:273-282. PMID: 23938869
  5. Brown, C. 2014. Core Facility Management In Career Alternatives for Biomedical Scientists Cold Spring Harbour Laboratory Press. NLM ID:101647626 [Book]
  6. Brown, C.M. 2014. Live-cell techniques - advances and challenges. Cell adhesion & migration. 8:429. PMID: 25603364
  7. Chang PK, Prenosil GA, Verbich D, Gill R, McKinney RA. 2014. Prolonged ampakine exposure prunes dendritic spines and increases presynaptic release probability for enhanced long-term potentiation in the hippocampus. Eur J Neurosci. 2014 Sep;40(5):2766-76. PMID:24925283
  8. Chen, J., N. Ingham, J. Kelly, S. Jadeja, D. Goulding, J. Pass, V.B. Mahajan, S.H. Tsang, A. Nijnik, I.J. Jackson, J.K. White, A. Forge, D. Jagger, and K.P. Steel. 2014. Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss. PLoS genetics. 10:e1004688. PMID: 25356849
  9. Eason, B., Young, D., Spurmanis, A.J., Wee,T.L. (E.), Kaufman,D., Brown, C.M. . 2014. Microscope maintenance and quality control: a practical guide. In Microscopy: advances in scientific research and education. A.Mendez-Vilas, editor. Formatex Research Center. [PDF]
  10. Fernandes, I., and F. Schock. 2014. The nebulin repeat protein Lasp regulates I-band architecture and filament spacing in myofibrils. The Journal of cell biology. 206:559-572. PMID: 25113030
  11. Gouspillou, G., N. Sgarioto, S. Kapchinsky, F. Purves-Smith, B. Norris, C.H. Pion, S. Barbat-Artigas, F. Lemieux, T. Taivassalo, J.A. Morais, M. Aubertin-Leheudre, and R.T. Hepple. 2014. Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans. FASEB J. 28:1621-1633. PMID: 24371120
  12. Gouspillou, G., N. Sgarioto, B. Norris, S. Barbat-Artigas, M. Aubertin-Leheudre, J.A. Morais, Y. Burelle, T. Taivassalo, and R.T. Hepple. 2014. The relationship between muscle fiber type-specific PGC-1alpha content and mitochondrial content varies between rodent models and humans. PloS one. 9:e103044. PMID: 25121500
  13. Hamlin, J.N., L.K. Schroeder, M. Fotouhi, H. Dokainish, M.S. Ioannou, M. Girard, N. Summerfeldt, P. Melancon, and P.S. McPherson. 2014. Scyl1 scaffolds class II Arfs to specific subcomplexes of coatomer through the gamma-COP appendage domain. Journal of cell science. 127:1454-1463. PMID: 24481816
  14. Hudson, J., J.R. Ha, V. Sabourin, R. Ahn, R. La Selva, J. Livingstone, L. Podmore, J. Knight, L. Forrest, N. Beauchemin, M. Hallett, M. Park, and J. Ursini-Siegel. 2014. p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition. Molecular and cellular biology. 34:3689-3701. PMID: 25071152
  15. Ilie, A., E. Weinstein, A. Boucher, R.A. McKinney, and J. Orlowski. 2014. Impaired posttranslational processing and trafficking of an endosomal Na+/H+ exchanger NHE6 mutant (Delta(370)WST(372)) associated with X-linked intellectual disability and autism. Neurochem Int. 73:192-203. PMID: 24090639
  16. Iliescu, A., M. Gravel, C. Horth, and P. Gros. 2014. Independent mutations at Arg181 and Arg274 of Vangl proteins that are associated with neural tube defects in humans decrease protein stability and impair membrane targeting. Biochemistry. 53:5356-5364. PMID: 25068569
  17. Iliescu, A., and P. Gros. 2014. The intracellular carboxyl terminal domain of Vangl proteins contains plasma membrane targeting signals. Protein Sci. 23:337-343. PMID: 24452931
  18. Iulita, M.F., S. Allard, L. Richter, L.M. Munter, A. Ducatenzeiler, C. Weise, S. Do Carmo, W.L. Klein, G. Multhaup, and A.C. Cuello. 2014. Intracellular Abeta pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study. Acta neuropathologica communications. 2:61. PMID: 24903713
  19. Jinadasa, T., E.Z. Szabo, M. Numat, and J. Orlowski. 2014. Activation of AMP-activated protein kinase regulates hippocampal neuronal pH by recruiting Na(+)/H(+) exchanger NHE5 to the cell surface. The Journal of biological chemistry. 289:20879-20897. PMID: 24936055
  20. Jonkman, J., C.M. Brown, and R.W. Cole. 2014. Quantitative confocal microscopy: beyond a pretty picture. Methods Cell Biol. 123:113-134. PMID: 24974025
  21. Khazaei, M.R., M.P. Girouard, R. Alchini, S. Ong Tone, T. Shimada, S. Bechstedt, M. Cowan, D. Guillet, P.W. Wiseman, G. Brouhard, J.F. Cloutier, and A.E. Fournier. 2014. Collapsin response mediator protein 4 regulates growth cone dynamics through the actin and microtubule cytoskeleton. The Journal of biological chemistry. 289:30133-30143. PMID: 25225289
  22. Kodiha, M., E. Hutter, S. Boridy, M. Juhas, D. Maysinger, and U. Stochaj. 2014. Gold nanoparticles induce nuclear damage in breast cancer cells, which is further amplified by hyperthermia. Cell Mol Life Sci. 71:4259-4273. PMID: 24740795
  23. Kumar, R., S. Turcaud, and L. Micouin. 2014. The Reaction of Dimethylalkynylaluminum Reagents with Trimethylsilyldiazomethane: Original Reactivity Leading to New alpha-Silylated Alkynyl Hydrazones. Org Lett. PMID: 25402443
  24. Lai, A.Z., S. Cory, H. Zhao, M. Gigoux, A. Monast, M.C. Guiot, S. Huang, A. Tofigh, C. Thompson, M. Naujokas, V.A. Marcus, N. Bertos, B. Sehat, R.M. Perera, E.S. Bell, B.D. Page, P.T. Gunning, L.E. Ferri, M. Hallett, and M. Park. 2014. Dynamic reprogramming of signaling upon met inhibition reveals a mechanism of drug resistance in gastric cancer. Sci Signal. 7:ra38. PMID: 24757178
  25. Larivière R, Gaudet R, Gentil BJ, Girard M, Conte TC, Minotti S, Leclerc-Desaulniers K, Gehring K, McKinney RA, Shoubridge EA, McPherson PS, Durham HD, Brais B. 2014. Sacs knockout mice present pathophysiological defects underlying autosomal recessive spastic ataxia of Charlevoix-Saguenay. Hum Mol Genet. 2014 Sep 26. pii: ddu491 PMID:25260547
  26. Lee, J.S., T.L. Wee, and C.M. Brown. 2014. Calibration of wide-field deconvolution microscopy for quantitative fluorescence imaging. Journal of biomolecular techniques : JBT. 25:31-40. PMID: 24688321 
  27. Lee, T., D. Di Paola, A. Malina, J.R. Mills, A. Kreps, F. Grosse, H. Tang, M. Zannis-Hadjopoulos, O. Larsson, and J. Pelletier. 2014. Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner. The Journal of biological chemistry. 289:22798-22814. PMID: 24990949
  28. Mahboubi, H., and U. Stochaj. 2014. Nucleoli and stress granules: connecting distant relatives. Traffic. 15:1179-1193. PMID: 24990581
  29. Malhotra, M., C. Tomaro-Duchesneau, S. Saha, and S. Prakash. 2014. Intranasal delivery of chitosan-siRNA nanoparticle formulation to the brain. Methods in molecular biology. 1141:233-247. PMID: 24567143
  30. Mayo, L., S.A. Trauger, M. Blain, M. Nadeau, B. Patel, J.I. Alvarez, I.D. Mascanfroni, A. Yeste, P. Kivisakk, K. Kallas, B. Ellezam, R. Bakshi, A. Prat, J.P. Antel, H.L. Weiner, and F.J. Quintana. 2014. Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation. Nature medicine. 20:1147-1156. PMID: 25216636
  31. Mille, F., L. Tamayo-Orrego, M. Levesque, M. Remke, A. Korshunov, J. Cardin, N. Bouchard, L. Izzi, M. Kool, P.A. Northcott, M.D. Taylor, S.M. Pfister, and F. Charron. 2014. The shh receptor boc promotes progression of early medulloblastoma to advanced tumors. Dev Cell. 31:34-47. PMID: 25263791
  32. Morquette B, Morquette P, Agostinone J, Feinstein E, McKinney RA, Kolta A, Di Polo A. 2014. REDD2-mediated inhibition of mTOR promotes dendrite retraction induced by axonal injury. Cell Death Differ. 2014 Sep 26. PMID:25257176
  33. Possik, E., Z. Jalali, Y. Nouet, M. Yan, M.C. Gingras, K. Schmeisser, L. Panaite, F. Dupuy, D. Kharitidi, L. Chotard, R.G. Jones, D.H. Hall, and A. Pause. 2014. Folliculin regulates ampk-dependent autophagy and metabolic stress survival. PLoS genetics. 10:e1004273. PMID: 24763318
  34. Prager-Khoutorsky, M., A. Khoutorsky, and C.W. Bourque. 2014. Unique interweaved microtubule scaffold mediates osmosensory transduction via physical interaction with TRPV1. Neuron. 83:866-878. PMID: 25123313
  35. Radovanovic, I., V. Leung, A. Iliescu, S.E. Bongfen, A. Mullick, D. Langlais, and P. Gros. 2014. Genetic control of susceptibility to Candida albicans in SM/J mice. Journal of immunology. 193:1290-1300. PMID: 24973457
  36. Ramdzan, Z.M., C. Vadnais, R. Pal, G. Vandal, C. Cadieux, L. Leduy, S. Davoudi, L. Hulea, L. Yao, A.N. Karnezis, M. Paquet, D. Dankort, and A. Nepveu. 2014. RAS transformation requires CUX1-dependent repair of oxidative DNA damage. PLoS biology. 12:e1001807. PMID: 24618719
  37. Rodrigue-Gervais, I.G., K. Labbe, M. Dagenais, J. Dupaul-Chicoine, C. Champagne, A. Morizot, A. Skeldon, E.L. Brincks, S.M. Vidal, T.S. Griffith, and M. Saleh. 2014. Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival. Cell host & microbe. 15:23-35. PMID: 24439895 
  38. Salem, S., D. Langlais, F. Lefebvre, G. Bourque, V. Bigley, M. Haniffa, J.L. Casanova, D. Burk, A. Berghuis, K.M. Butler, T.R. Leahy, S. Hambleton, and P. Gros. 2014. Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8K108E mutation. Blood. PMID: 25122610
  39. Sattel, H., R. Schaefert, W. Hauser, M. Herrmann, J. Ronel, P. Henningsen, and C. Hausteiner-Wiehle. 2014. [Treatment of non-specific, functional and somatoform bodily complaints]. Dtsch Med Wochenschr. 139:602-607. PMID: 24619719
  40. Schreij, A.M., M. Chaineau, W. Ruan, S. Lin, P.A. Barker, E.A. Fon, and P.S. McPherson. 2014. LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation. EMBO Rep. PMID: 25427558
  41. Upton, J.W., and H. Sridharan. 2014. InFLUencing host survival: cIAP2 tips the scales. Cell host & microbe. 15:3-5. PMID: 24439892
  42. Vadnais, C., P. Shooshtarizadeh, C.V. Rajadurai, R. Lesurf, L. Hulea, S. Davoudi, C. Cadieux, M. Hallett, M. Park, and A. Nepveu. 2014. Autocrine Activation of the Wnt/beta-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers. Biology open. 3:937-946. PMID: 25217618 
  43. Zhang, X., S. Shastry, S.E. Bradforth, and J.L. Nadeau. 2014. Nuclear uptake of ultrasmall gold-doxorubicin conjugates imaged by fluorescence lifetime imaging microscopy (FLIM) and electron microscopy. Nanoscale. PMID: 25407725 

 

2013

  1. Apaja, P.M., B. Foo, T. Okiyoneda, W.C. Valinsky, H. Barriere, R. Atanasiu, E. Ficker, G.L. Lukacs, and A. Shrier. 2013. Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane. Molecular biology of the cell. 24:3787-3804. PMID: 24152733
  2. Arabzadeh, A., C. Chan, A.L. Nouvion, V. Breton, S. Benlolo, L. DeMarte, C. Turbide, P. Brodt, L. Ferri, and N. Beauchemin. 2013. Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer. Oncogene. 32:849-860. PMID: 22469976
  3. Ayoub, E., A. Hall, A.M. Scott, M.J. Chagnon, G. Miquel, M. Halle, M. Noda, A. Bikfalvi, and M.L. Tremblay. 2013. Regulation of the Src kinase-associated phosphoprotein 55 homologue by the protein tyrosine phosphatase PTP-PEST in the control of cell motility. The Journal of biological chemistry. 288:25739-25748. PMID: 23897807
  4. Blanchette, P., P. Wimmer, F. Dallaire, C.Y. Cheng, and P.E. Branton. 2013. Aggresome formation by the adenoviral protein E1B55K is not conserved among adenovirus species and is not required for efficient degradation of nuclear substrates. J Virol. 87:4872-4881. PMID: 23408624
  5. Broussard, J.A., B. Rappaz, D.J. Webb, and C.M. Brown. 2013. Fluorescence resonance energy transfer microscopy as demonstrated by measuring the activation of the serine/threonine kinase Akt. Nat Protoc. 8:265-281. PMID: 23306460
  6. Chang PK, Boridy S, McKinney RA#, Maysinger D.#(#joint Senior) .2013. Letrozole potentiates Mitochondria and Dendritic Spine Impairments induced by β Amyloid. J Aging Res. [PDF]
  7. Cheng, C.Y., T. Gilson, P. Wimmer, S. Schreiner, G. Ketner, T. Dobner, P.E. Branton, and P. Blanchette. 2013. Role of E1B55K in E4orf6/E1B55K E3 ligase complexes formed by different human adenovirus serotypes. J Virol. 87:6232-6245. PMID:23536656
  8. Cole, R.W., M. Thibault, C.J. Bayles, B. Eason, A.M. Girard, T. Jinadasa, C. Opansky, K. Schulz, and C.M. Brown. 2013. International test results for objective lens quality, resolution, spectral accuracy and spectral separation for confocal laser scanning microscopes. Microsc Microanal. 19:1653-1668. PMID:24103552
  9. Collins, H., and N.S. Moon. 2013. The components of Drosophila histone chaperone dCAF-1 are required for the cell death phenotype associated with rbf1 mutation. G3. 3:1639-1647.PMID: 23893745
  10. Deane, E.C., A.E. Ilie, S. Sizdahkhani, M. Das Gupta, J. Orlowski, and R.A. McKinney. 2013. Enhanced recruitment of endosomal Na+/H+ exchanger NHE6 into Dendritic spines of hippocampal pyramidal neurons during NMDA receptor-dependent long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33:595-610. [PDF]
  11. Ellis, S.J., B.T. Goult, M.J. Fairchild, N.J. Harris, J. Long, P. Lobo, S. Czerniecki, F. Van Petegem, F. Schock, M. Peifer, and G. Tanentzapf. 2013. Talin autoinhibition is required for morphogenesis. Current biology : CB. 23:1825-1833. PMID:24012314
  12. Gill R, Chang PK, Prenosil GA, Deane EC, McKinney RA. 2013. Blocking brain-derived neurotrophic factor inhibits injury-induced hyperexcitability of hippocampal CA3 neurons. Eur J Neurosci.Dec;38(11):3554-66 PMID:24118418
  13. Gkogkas, C.G., A. Khoutorsky, I. Ran, E. Rampakakis, T. Nevarko, D.B. Weatherill, C. Vasuta, S. Yee, M. Truitt, P. Dallaire, F. Major, P. Lasko, D. Ruggero, K. Nader, J.C. Lacaille, and N. Sonenberg. 2013. Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature. 493:371-377. PMID: 23172145
  14. Hernandez, G., M. Miron, H. Han, N. Liu, J. Magescas, G. Tettweiler, F. Frank, N. Siddiqui, N. Sonenberg, and P. Lasko. 2013. Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster. Molecular and cellular biology. 33:2854-2864. PMID: 23716590
  15. Katzemich, A., K.A. Liao, S. Czerniecki, and F. Schock. 2013. Alp/Enigma family proteins cooperate in Z-disc formation and myofibril assembly. PLoS genetics. 9:e1003342. PMID: 23505387
  16. Khoutorsky, A., A. Yanagiya, C.G. Gkogkas, M.R. Fabian, M. Prager-Khoutorsky, R. Cao, K. Gamache, F. Bouthiette, A. Parsyan, R.E. Sorge, J.S. Mogil, K. Nader, J.C. Lacaille, and N. Sonenberg. 2013. Control of synaptic plasticity and memory via suppression of poly(A)-binding protein. Neuron. 78:298-311. PMID: 23622065
  17. Knight, J.F., R. Lesurf, H. Zhao, D. Pinnaduwage, R.R. Davis, S.M. Saleh, D. Zuo, M.A. Naujokas, N. Chughtai, J.I. Herschkowitz, A. Prat, A.M. Mulligan, W.J. Muller, R.D. Cardiff, J.P. Gregg, I.L. Andrulis, M.T. Hallett, and M. Park. 2013. Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer. Proc Natl Acad Sci U S A. 110:E1301-1310. PMID: 23509284
  18. Krawchuk, D., N. Honma-Yamanaka, S. Anani, and Y. Yamanaka. 2013. FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst. Developmental biology. 384:65-71. PMID: 24063807
  19. Krivy, K., M.R. Bradley-Gill, and N.S. Moon. 2013. Capicua regulates proliferation and survival of RB-deficient cells in Drosophila. Biology open. 2:183-190. PMID: 23429853
  20. Krumova, K., L.E. Greene, and G. Cosa. 2013. Fluorogenic alpha-tocopherol analogue for monitoring the antioxidant status within the inner mitochondrial membrane of live cells. Journal of the American Chemical Society. 135:17135-17143. [PDF]
  21. Lacoste, J., K. Young, and C.M. Brown. 2013. Live-cell migration and adhesion turnover assays. Methods in molecular biology. 931:61-84. PMID: 23026997
  22. Lawrence, E.J., and C.A. Mandato. 2013. Mitochondria localize to the cleavage furrow in mammalian cytokinesis. PloS one. 8:e72886. PMID: 23991162
  23. Lukashova, V., T. Jinadasa, A. Ilie, D. Verbich, E. Cooper, and J. Orlowski. 2013. The Na(+)/H (+) exchanger NHE5 is sorted to discrete intracellular vesicles in the central and peripheral nervous systems. Advances in experimental medicine and biology. 961:397-410. PMID: 23224898
  24. Machnes ZM, Huang TC, Chang PK, Gill R, Reist N, Dezsi G, Ozturk E, Charron F, O'Brien TJ, Jones NC, McKinney RA#, Szyf M#.(#Joint Senior) .2013. DNA Methylation Mediates Persistent Epileptiform Activity In Vivo and In Vitro.  PLoS One. 2013 Oct 2;8(10):e76299 PMID: 2409846
  25. Ngan, E., J.J. Northey, C.M. Brown, J. Ursini-Siegel, and P.M. Siegel. 2013. A complex containing LPP and alpha-actinin mediates TGFbeta-induced migration and invasion of ErbB2-expressing breast cancer cells. Journal of cell science. 126:1981-1991. PMID: 23447672
  26. Papapietro, O., S. Teatero, A. Thanabalasuriar, K.E. Yuki, E. Diez, L. Zhu, E. Kang, S. Dhillon, A.M. Muise, Y. Durocher, M.M. Marcinkiewicz, D. Malo, and S. Gruenheid. 2013. R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea. Nature communications. 4:1898. PMID: 23695692 
  27. Stewart, K., N. Uetani, W. Hendriks, M.L. Tremblay, and M. Bouchard. 2013. Inactivation of LAR family phosphatase genes Ptprs and Ptprf causes craniofacial malformations resembling Pierre-Robin sequence. Development. 140:3413-3422. PMID: 23863482
  28. Thanabalasuriar, A., J. Kim, and S. Gruenheid. 2013. The inhibition of COPII trafficking is important for intestinal epithelial tight junction disruption during enteropathogenic Escherichia coli and Citrobacter rodentium infection. Microbes Infect. 15:738-744. PMID: 23747681
  29. Webb, D.J., and C.M. Brown. 2013. Epi-fluorescence microscopy. Methods in molecular biology. 931:29-59. PMID: 23026996

 

2012

  1. Aswani, K., T. Jinadasa, and C.M. Brown. 2012. “Fluorescence Microscopy Light Sources”. Microscopy Today. 20:22-28. [PDF] 
  2. Bouaouina, M., K. Jani, J.Y. Long, S. Czerniecki, E.M. Morse, S.J. Ellis, G. Tanentzapf, F. Schock, and D.A. Calderwood. 2012. Zasp regulates integrin activation. Journal of cell science. 125:5647-5657. [PDF]
  3. Broussard, J.A., W.H. Lin, D. Majumdar, B. Anderson, B. Eason, C.M. Brown, and D.J. Webb. 2012. The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration. Molecular biology of the cell. 23:1486-1499. PMID:22379109
  4.  Chang, P.K.Y., Verbich, D., and McKinney R.A. (2012) AMPA receptors as drug targets in neurological disease: caveats and advantage. Eur J Neurosci 35: 1098-1916 (CIHR and NSERC funded) PMID: 22708602 
  5. D'Antoni, M.L., P.-A. Risse, P. Ferraro, J.G. Martin, and M.S. Ludwig. 2012. Effects of decorin and biglycan on human airway smooth muscle cell adhesion. Matrix Biology. 31:101-112. PMID: 22155154
  6. Fathers, K.E., E.S. Bell, C.V. Rajadurai, S. Cory, H. Zhao, A. Mourskaia, D. Zuo, J. Madore, A. Monast, A.M. Mes-Masson, A.A. Grosset, L. Gaboury, M. Hallet, P. Siegel, and M. Park. 2012. Crk adaptor proteins act as key signaling integrators for breast tumorigenesis. Breast Cancer Res. 14:R74. PMID: 22569336
  7. Fonseca, B.D., G.H. Diering, M.A. Bidinosti, K. Dalal, T. Alain, A.D. Balgi, R. Forestieri, M. Nodwell, C.V. Rajadurai, C. Gunaratnam, A.R. Tee, F. Duong, R.J. Andersen, J. Orlowski, M. Numata, N. Sonenberg, and M. Roberge. 2012. Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling. The Journal of biological chemistry. 287:17530-17545. PMID: 22474287
  8. Hernandez, G., H. Han, V. Gandin, L. Fabian, T. Ferreira, J. Zuberek, N. Sonenberg, J.A. Brill, and P. Lasko. 2012. Eukaryotic initiation factor 4E-3 is essential for meiotic chromosome segregation, cytokinesis and male fertility in Drosophila. Development. 139:3211-3220. PMID: 22833128
  9. Hossain, S., M.A. de la Cruz-Morcillo, R. Sanchez-Prieto, and G. Almazan. 2012. Mitogen-activated protein kinase p38 regulates Krox-20 to direct Schwann cell differentiation and peripheral myelination. Glia. 60:1130-1144. PMID: 22511272 
  10. Katzemich, A., N. Kreiskother, A. Alexandrovich, C. Elliott, F. Schock, K. Leonard, J. Sparrow, and B. Bullard. 2012. The function of the M-line protein obscurin in controlling the symmetry of the sarcomere in the flight muscle of Drosophila. Journal of cell science. 125:3367-3379. PMID: 22467859
  11. Lacoste, J., K. Young, et al. 2012. Live-Cell Migration and Adhesion Turnover Assays. Methods Mol Biol.
  12. Lai, A.Z., M. Durrant, D. Zuo, C.D. Ratcliffe, and M. Park. 2012. Met kinase-dependent loss of the E3 ligase Cbl in gastric cancer. The Journal of biological chemistry. 287:8048-8059. PMID: 22262855
  13. Ling, C., V. M. Su, et al. 2012. Loss of the 14-3-3sigma tumor suppressor is a critical event in ErbB2-mediated tumor progression. Cancer Discov 2(1): 68-81.
  14. McGuire, H., M.R. Aurousseau, D. Bowie, and R. Blunck. 2012. Automating single subunit counting of membrane proteins in mammalian cells. The Journal of biological chemistry. 287:35912-35921. PMID: 22930752
  15. Penney, J., K. Tsurudome, E.H. Liao, F. Elazzouzi, M. Livingstone, M. Gonzalez, N. Sonenberg, and A.P. Haghighi. 2012. TOR Is Required for the Retrograde Regulation of Synaptic Homeostasis at the Drosophila Neuromuscular Junction. Neuron. 74:166-178. PMID: 22500638
  16. Picard, M., B. Jung, F. Liang, I. Azuelos, S. Hussain, P. Goldberg, R. Godin, G. Danialou, R. Chaturvedi, K. Rygiel, S. Matecki, S. Jaber, C. Des Rosiers, G. Karpati, L. Ferri, Y. Burelle, D.M. Turnbull, T. Taivassalo, and B.J. Petrof. 2012. Mitochondrial dysfunction and lipid accumulation in the human diaphragm during mechanical ventilation. Am J Respir Crit Care Med. 186:1140-1149. PMID: 23024021
  17. Rajadurai, C.V., S. Havrylov, K. Zaoui, R. Vaillancourt, M. Stuible, M. Naujokas, D. Zuo, M.L. Tremblay, and M. Park. 2012. Met receptor tyrosine kinase signals through a cortactin-Gab1 scaffold complex, to mediate invadopodia. Journal of cell science. 125:2940-2953. PMID: 22366451
  18. Sharma, A., G.M. Soliman, N. Al-Hajaj, R. Sharma, D. Maysinger, and A. Kakkar. 2012. Design and evaluation of multifunctional nanocarriers for selective delivery of coenzyme Q10 to mitochondria. Biomacromolecules. 13:239-252. [PDF]
  19. Veit, G., F. Bossard, J. Goepp, A.S. Verkman, L.J. Galietta, J.W. Hanrahan, and G.L. Lukacs. 2012. Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Molecular biology of the cell. 23:4188-4202. PMID: 22973054 
  20. Zaun, H.C., A. Shrier, and J. Orlowski. 2012. N-myristoylation and Ca2+ binding of calcineurin B homologous protein CHP3 are required to enhance Na+/H+ exchanger NHE1 half-life and activity at the plasma membrane. The Journal of biological chemistry. 287:36883-36895. PMID: 22984264 
  21. Zhang, X., H. Chibli, D. Kong, and J. Nadeau. 2012. Comparative cytotoxicity of gold-doxorubicin and InP-doxorubicin conjugates. Nanotechnology. 23:275103. PMID: 22710097

 

2011

  1. Barriere, H., P. Apaja, T. Okiyoneda, and G.L. Lukacs. 2011. Endocytic Sorting of CFTR Variants Monitored by Single-Cell Fluorescence Ratiometric Image Analysis (FRIA) in Living Cells. Methods in molecular biology. 741:301-317. PMID: 21594793
  2. Berretta, F., J. St-Pierre, C.A. Piccirillo, and M.M. Stevenson. 2011. IL-2 contributes to maintaining a balance between CD4+Foxp3+ regulatory T cells and effector CD4+ T cells required for immune control of blood-stage malaria infection. Journal of immunology. 186:4862-4871. PMID: 21389253
  3. Chen, J., G. Stefano, F. Brandizzi, and H. Zheng. 2011. Arabidopsis RHD3 mediates the generation of the tubular ER network and is required for Golgi distribution and motility in plant cells. Journal of cell science. 124:2241-2252. PMID: 21652628 
  4. Cheng, C.Y., T. Gilson, F. Dallaire, G. Ketner, P.E. Branton, and P. Blanchette. 2011. The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity. Journal of virology. 85:765-775. PMID: 21068234 
  5. Chibli, H., L. Carlini, S. Park, N.M. Dimitrijevic, and J.L. Nadeau. 2011. Cytotoxicity of InP/ZnS quantum dots related to reactive oxygen species generation. Nanoscale. 3:2552-2559. PMID: 21509403 
  6. Cole, R.W., T. Jinadasa, and C.M. Brown. 2011. Measuring and interpreting point spread functions to determine confocal microscope resolution and ensure quality control. Nat Protoc. 6:1929-1941. PMID: 22082987
  7. Gawri, R., F. Mwale, J. Ouellet, P. Roughley, T. Steffen, J. Antoniou, and L. Haglund. 2011. Development of an organ culture system for long term survival of the intact human intervertebral disc. Spine. PMID: 21270705 
  8. Grenier, L., B. Robaire, and B.F. Hales. 2011. Paternal cyclophosphamide exposure induces the formation of functional micronuclei during the first zygotic division. PloS one. 6:e27600. PMID: 22110683
  9. Iliescu, A., M. Gravel, C. Horth, S. Apuzzo, and P. Gros. 2011. Transmembrane topology of mammalian planar cell polarity protein Vangl1. Biochemistry. 50:2274-2282. PMID: 21291170
  10. Iliescu, A., M. Gravel, C. Horth, Z. Kibar, and P. Gros. 2011. Loss of membrane targeting of Vangl proteins causes neural tube defects. Biochemistry. 50:795-804. PMID: 21142127
  11. Jim, B., T. Steffen, J. Moir, P. Roughley, and L. Haglund. 2011. Development of an intact intervertebral disc organ culture system in which degeneration can be induced as a prelude to studying repair potential. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. PMID: 21336509
  12. Katzemich, A., J.Y. Long, K. Jani, B.R. Lee, and F. Schock. 2011. Muscle type-specific expression of Zasp52 isoforms in Drosophila. Gene expression patterns : GEP. 11:484-490. PMID: 21867777
  13. Kodiha, M., D. Ho-Wo-Cheong, and U. Stochaj. 2011. Pharmacological AMP-kinase activators have compartment-specific effects on cell physiology. American journal of physiology. Cell physiology. 301:C1307-1315. PMID: 21918180
  14. Lacoste, J., C. Vining, D. Zuo, A. Spurmanis, and C.M. Brown. 2011. Optimal Conditions for Live Cell Microscopy and Raster Image Correlation Spectroscopy (RICS). In Annual Reviews in Fluorescence 2009. C.D. Geddes, editor. [PDF]
  15. Parachoniak, C.A., Y. Luo, J.V. Abella, J.H. Keen, and M. Park. 2011. GGA3 Functions as a Switch to Promote Met Receptor Recycling, Essential for Sustained ERK and Cell Migration. Developmental cell. 20:751-763. PMID: 21664574
  16. Picard, M., T. Taivassalo, D. Ritchie, K.J. Wright, M.M. Thomas, C. Romestaing, and R.T. Hepple. 2011. Mitochondrial structure and function are disrupted by standard isolation methods. PloS one. 6:e18317. PMID: 21512578
  17. Qi, X., M. Kaneda, J. Chen, A. Geitmann, and H. Zheng. 2011. A specific role for Arabidopsis TRAPPII in post-Golgi Trafficking that is Crucial for Cytokinesis and Cell Polarity. The Plant journal : for cell and molecular biology. PMID: 21689172
  18. Refaei, M., R. Leventis, and J.R. Silvius. 2011. Assessment of the Roles of Ordered Lipid Microdomains in Post-Endocytic Trafficking of Glycosyl-Phosphatidylinositol-Anchored Proteins in Mammalian Fibroblasts. Traffic. PMID: 21696526
  19. Rohn, J.L., D. Sims, T. Liu, M. Fedorova, F. Schock, J. Dopie, M.K. Vartiainen, A.A. Kiger, N. Perrimon, and B. Baum. 2011. Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype. The Journal of cell biology. 194:789-805. PMID: 21893601
  20. Sangwan, V., J. Abella, A. Lai, N. Bertos, M. Stuible, M.L. Tremblay, and M. Park. 2011. Protein-tyrosine phosphatase 1B modulates early endosome fusion and trafficking of Met and epidermal growth factor receptors. The Journal of biological chemistry. 286:45000-45013. PMID: 22045810
  21. Sansregret, L., C. Vadnais, J. Livingstone, N. Kwiatkowski, A. Awan, C. Cadieux, L. Leduy, M.T. Hallett, and A. Nepveu. 2011. Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure. Proceedings of the National Academy of Sciences of the United States of America. 108:1949-1954. [PDF]
  22. Tran, S.D., R.S. Redman, A.J. Barrett, S.Z. Pavletic, S. Key, Y. Liu, A. Carpenter, H.M. Nguyen, Y. Sumita, B.J. Baum, S.R. Pillemer, and E. Mezey. 2011. Microchimerism in salivary glands after blood- and marrow-derived stem cell transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 17:429-433. PMID: 20940057
  23. Wahba, A.S., F. Azizi, G.F. Deleavey, C. Brown, F. Robert, M. Carrier, A. Kalota, A.M. Gewirtz, J. Pelletier, R.H. Hudson, and M.J. Damha. 2011. Phenylpyrrolocytosine as an unobtrusive base modification for monitoring activity and cellular trafficking of siRNA. ACS Chem Biol. 6:912-919. PMID: 21667942
  24. Webb, D. J., & Brown, C. M. 2011. Epi-Fluorescence Microscopy. In D. J. Taatjes & J. Roth (Eds.), Cell Imaging Techniques: Methods and Protocols (Vol. Second Edition): Humana Press.
  25. Zhang, T., B. Dayanandan, I. Rouiller, E.J. Lawrence, and C.A. Mandato. 2011. Growth-arrest-specific protein 2 inhibits cell division in Xenopus embryos. PloS one. 6:e24698. PMID: 21931817
  26. Zhang, X., H. Chibli, R. Mielke, and J. Nadeau. 2011. Ultrasmall gold-doxorubicin conjugates rapidly kill apoptosis-resistant cancer cells. Bioconjugate chemistry. 22:235-243. PMID: 21189001
  27. Zhu, T., J.A. Mancini, P. Sapieha, C. Yang, J.S. Joyal, J.C. Honore, M. Leduc, K. Zaniolo, P. Hardy, Z. Shao, L. Fan, X. Hou, G.E. Rivard, and S. Chemtob. 2011. Cortactin activation by FVIIa/tissue factor and PAR2 promotes endothelial cell migration. American journal of physiology. Regulatory, integrative and comparative physiology. 300:R577-585. PMID: 21160057

 

2010

  1. Abella, J.V., C.A. Parachoniak, V. Sangwan, and M. Park. 2010. Dorsal ruffle microdomains potentiate Met receptor tyrosine kinase signaling and down-regulation. The Journal of biological chemistry. 285:24956-24967.
  2. Abella, J.V., R. Vaillancourt, M.M. Frigault, M.G. Ponzo, D. Zuo, V. Sangwan, L. Larose, and M. Park. 2010. The Gab1 scaffold regulates RTK-dependent dorsal ruffle formation through the adaptor Nck. Journal of cell science. 123:1306-1319.
  3. An, B.S., L.E. Tavera-Mendoza, V. Dimitrov, X. Wang, M.R. Calderon, H.J. Wang, and J.H. White. 2010. Stimulation of Sirt1-regulated FoxO protein function by the ligand-bound vitamin D receptor. Molecular and cellular biology. 30:4890-4900.
  4. Apaja, P.M., H. Xu, and G.L. Lukacs. 2010. Quality control for unfolded proteins at the plasma membrane. The Journal of cell biology. 191:553-570.
  5. Ball, R.W., M. Warren-Paquin, K. Tsurudome, E.H. Liao, F. Elazzouzi, C. Cavanagh, B.S. An, T.T. Wang, J.H. White, and A.P. Haghighi. 2010. Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons. Neuron. 66:536-549.
  6. Banski, P., H. Mahboubi, M. Kodiha, S. Shrivastava, C. Kanagaratham, and U. Stochaj. 2010. Nucleolar targeting of the chaperone hsc70 is regulated by stress, cell signaling, and a composite targeting signal which is controlled by autoinhibition. The Journal of biological chemistry. 285:21858-21867.
  7. Bhagatji, P., R. Leventis, R. Rich, C.J. Lin, and J.R. Silvius. 2010. Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane. Biophysical journal. 99:3327-3335.
  8. Ceni, C., R.P. Kommaddi, R. Thomas, E. Vereker, X. Liu, P.S. McPherson, B. Ritter, and P.A. Barker. 2010. The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling. Journal of cell science. 123:2299-2307.
  9. Chang, N.C., M. Nguyen, M. Germain, and G.C. Shore. 2010. Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. The EMBO journal. 29:606-618.
  10. Clarke, S., R.E. Mielke, A. Neal, P. Holden, and J.L. Nadeau. 2010. Bacterial and mineral elements in an arctic biofilm: a correlative study using fluorescence and electron microscopy. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 16:153-165.
  11. Contreras, I., M.A. Gomez, O. Nguyen, M.T. Shio, R.W. McMaster, and M. Olivier. 2010. Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63. PLoS pathogens. 6:e1001148.
  12. Cui, Q.L., G. Fragoso, V.E. Miron, P.J. Darlington, W.E. Mushynski, J. Antel, and G. Almazan. 2010. Response of human oligodendrocyte progenitors to growth factors and axon signals. Journal of neuropathology and experimental neurology. 69:930-944.
  13. Gravel, M., A. Iliescu, C. Horth, S. Apuzzo, and P. Gros. 2010. Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse. Biochemistry. 49:3445-3455.
  14. Haghayeghi, A., A. Sarac, S. Czerniecki, J. Grosshans, and F. Schock. 2010. Pellino enhances innate immunity in Drosophila. Mechanisms of development. 127:301-307.
  15. Haines, J.D., J. Fang, W.E. Mushynski, and G. Almazan. 2010. Mitogen-activated protein kinase activated protein kinase 2 (MK2) participates in p38 MAPK regulated control of oligodendrocyte differentiation. Glia. 58:1384-1393.
  16. Hossain, S., G. Fragoso, W.E. Mushynski, and G. Almazan. 2010. Regulation of peripheral myelination by Src-like kinases. Experimental neurology. 226:47-57.
  17. Hourani, R., M. Jain, D. Maysinger, and A. Kakkar. 2010. Multi-tasking with single platform dendrimers for targeting sub-cellular microenvironments. Chemistry. 16:6164-6168.
  18. Hutter, E., S. Boridy, S. Labrecque, M. Lalancette-Hebert, J. Kriz, F.M. Winnik, and D. Maysinger. 2010. Microglial response to gold nanoparticles. ACS nano. 4:2595-2606.
  19. Khila, A., and E. Abouheif. 2010. Evaluating the role of reproductive constraints in ant social evolution. Philos Trans R Soc Lond B Biol Sci. 365:617-630.
  20. Kodiha, M., N. Crampton, S. Shrivastava, R. Umar, and U. Stochaj. 2010. Traffic control at the nuclear pore. Nucleus. 1:237-244.
  21. Laplante, C., S.M. Paul, G.J. Beitel, and L.A. Nilson. 2010. Echinoid regulates tracheal morphology and fusion cell fate in Drosophila. Developmental dynamics : an official publication of the American Association of Anatomists. 239:2509-2519.
  22. LeSimple, P., J. Liao, R. Robert, D.C. Gruenert, and J.W. Hanrahan. 2010. Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers. J Physiol. 588:1195-1209.
  23. Ling, C., D. Zuo, B. Xue, S. Muthuswamy, and W.J. Muller. 2010. A novel role for 14-3-3sigma in regulating epithelial cell polarity. Genes & development. 24:947-956.
  24. Maghzal, N., E. Vogt, W. Reintsch, J.S. Fraser, and F. Fagotto. 2010. The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling. The Journal of cell biology. 191:645-659.
  25. Milev, M.P., C.M. Brown, and A.J. Mouland. 2010. Live cell visualization of the interactions between HIV-1 Gag and the cellular RNA-binding protein Staufen1. Retrovirology. 7:41.
  26. Miron, V.E., S.K. Ludwin, P.J. Darlington, A.A. Jarjour, B. Soliven, T.E. Kennedy, and J.P. Antel. 2010. Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices. The American journal of pathology. 176:2682-2694.
  27. Nouvion, A.L., M. Oubaha, S. Leblanc, E.C. Davis, H. Jastrow, R. Kammerer, V. Breton, C. Turbide, S. Ergun, J.P. Gratton, and N. Beauchemin. 2010. CEACAM1: a key regulator of vascular permeability. Journal of cell science. 123:4221-4230.
  28. Pontier, S.M., L. Huck, D.E. White, J. Rayment, V. Sanguin-Gendreau, B. Hennessy, D. Zuo, R. St-Arnaud, G.B. Mills, S. Dedhar, C.J. Marshall, and W.J. Muller. 2010. Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer. Oncogene. 29:3374-3385.
  29. Robert, R., G.W. Carlile, J. Liao, H. Balghi, P. Lesimple, N. Liu, B. Kus, D. Rotin, M. Wilke, H.R. de Jonge, B.J. Scholte, D.Y. Thomas, and J.W. Hanrahan. 2010. Correction of the Delta phe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine. Mol Pharmacol. 77:922-930.
  30. Rouleau, L., I.B. Copland, J.C. Tardif, R. Mongrain, and R.L. Leask. 2010. Neutrophil adhesion on endothelial cells in a novel asymmetric stenosis model: effect of wall shear stress gradients. Annals of biomedical engineering. 38:2791-2804.
  31. Rouleau, L., J. Rossi, and R.L. Leask. 2010. Concentration and time effects of dextran exposure on endothelial cell viability, attachment, and inflammatory marker expression in vitro. Annals of biomedical engineering. 38:1451-1462.
  32. Stuible, M., J.V. Abella, M. Feldhammer, M. Nossov, V. Sangwan, B. Blagoev, M. Park, and M.L. Tremblay. 2010. PTP1B targets the endosomal sorting machinery: dephosphorylation of regulatory sites on the endosomal sorting complex required for transport component STAM2. The Journal of biological chemistry. 285:23899-23907.
  33. Sukarieh, R., N. Sonenberg, and J. Pelletier. 2010. Nuclear assortment of eIF4E coincides with shut-off of host protein synthesis upon poliovirus infection. The Journal of general virology. 91:1224-1228.
  34. Tsurudome, K., K. Tsang, E.H. Liao, R. Ball, J. Penney, J.S. Yang, F. Elazzouzi, T. He, A. Chishti, G. Lnenicka, E.C. Lai, and A.P. Haghighi. 2010. The Drosophila miR-310 cluster negatively regulates synaptic strength at the neuromuscular junction. Neuron. 68:879-893.
  35. Ursini-Siegel, J., S. Cory, D. Zuo, W.R. Hardy, E. Rexhepaj, S. Lam, B. Schade, K. Jirstrom, E. Bjur, C.A. Piccirillo, D. Denardo, L.M. Coussens, D.J. Brennan, W.M. Gallagher, M. Park, T. Pawson, M. Hallett, and W.J. Muller. 2010. Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response. Cancer research. 70:7776-7787.
  36. Van Der Kraak, L., C. Meunier, C. Turbide, S. Jothy, L. Gaboury, V. Marcus, S.Y. Chang, N. Beauchemin, and P. Gros. 2010. A two-locus system controls susceptibility to colitis-associated colon cancer in mice. Oncotarget. 1:436-446.
  37. Walker, V.E., M.J. Wong, R. Atanasiu, C. Hantouche, J.C. Young, and A. Shrier. 2010. Hsp40 chaperones promote degradation of the HERG potassium channel. The Journal of biological chemistry. 285:3319-3329.
  38. Xu, B., J.S. Goldman, V.V. Rymar, C. Forget, P.S. Lo, S.J. Bull, E. Vereker, P.A. Barker, L.E. Trudeau, A.F. Sadikot, and T.E. Kennedy. 2010. Critical roles for the netrin receptor deleted in colorectal cancer in dopaminergic neuronal precursor migration, axon guidance, and axon arborization. Neuroscience. 169:932-949.
  39. Yang, C., C. Gagnon, X. Hou, and P. Hardy. 2010. Low density lipoprotein receptor mediates anti-VEGF effect of lymphocyte T-derived microparticles in Lewis lung carcinoma cells. Cancer biology & therapy. 10:448-456.
  40. Yang, W., and S. Hekimi. 2010. A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS biology. 8:e1000556.
  41. Zhan, Y., N.Y. Melian, M. Pantoja, N. Haines, H. Ruohola-Baker, C.W. Bourque, Y. Rao, and S. Carbonetto. 2010. Dystroglycan and mitochondrial ribosomal protein l34 regulate differentiation in the Drosophila eye. PloS one. 5:e10488.

 

2009

  1. Barriere, H., M. Bagdany, F. Bossard, T. Okiyoneda, G. Wojewodka, D. Gruenert, D. Radzioch, and G.L. Lukacs. 2009. Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles. Molecular biology of the cell. 20:3125-3141.
  2. Bertrand, M.J., K. Doiron, K. Labbe, R.G. Korneluk, P.A. Barker, and M. Saleh. 2009. Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2. Immunity. 30:789-801.
  3. Bhagatji, P., R. Leventis, J. Comeau, M. Refaei, and J.R. Silvius. 2009. Steric and not structure-specific factors dictate the endocytic mechanism of glycosylphosphatidylinositol-anchored proteins. The Journal of cell biology. 186:615-628.
  4. Boridy, S., H. Takahashi, K. Akiyoshi, and D. Maysinger. 2009. The binding of pullulan modified cholesteryl nanogels to Abeta oligomers and their suppression of cytotoxicity. Biomaterials. 30:5583-5591.
  5. Caceres, L., and L.A. Nilson. 2009. Translational repression of gurken mRNA in the Drosophila oocyte requires the hnRNP Squid in the nurse cells. Developmental biology. 326:327-334.
  6. Chevallier, J., C. Koop, A. Srivastava, R.J. Petrie, N. Lamarche-Vane, and J.F. Presley. 2009. Rab35 regulates neurite outgrowth and cell shape. FEBS letters. 583:1096-1101.
  7. Crampton, N., M. Kodiha, S. Shrivastava, R. Umar, and U. Stochaj. 2009. Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1. Molecular biology of the cell. 20:5106-5116.
  8. Czachorowski, M., S. Lam-Yuk-Tseung, M. Cellier, and P. Gros. 2009. Transmembrane topology of the mammalian Slc11a2 iron transporter. Biochemistry. 48:8422-8434.
  9. Dallaire, F., P. Blanchette, and P.E. Branton. 2009. A proteomic approach to identify candidate substrates of human adenovirus E4orf6-E1B55K and other viral cullin-based E3 ubiquitin ligases. Journal of virology. 83:12172-12184.
  10. Dallaire, F., P. Blanchette, P. Groitl, T. Dobner, and P.E. Branton. 2009. Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex. Journal of virology. 83:5329-5338.
  11. Divangahi, M., H. Balghi, G. Danialou, A.S. Comtois, A. Demoule, S. Ernest, C. Haston, R. Robert, J.W. Hanrahan, D. Radzioch, and B.J. Petrof. 2009. Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis mice. PLoS genetics. 5:e1000586.
  12. Fan, J., M.B. Rone, and V. Papadopoulos. 2009. Translocator protein 2 is involved in cholesterol redistribution during erythropoiesis. The Journal of biological chemistry. 284:30484-30497.
  13. Frigault, M.M., J. Lacoste, J.L. Swift, and C.M. Brown. 2009. Live-cell microscopy - tips and tools. Journal of cell science. 122:753-767.
  14. Huot, M.E., C.M. Brown, N. Lamarche-Vane, and S. Richard. 2009. An adaptor role for cytoplasmic Sam68 in modulating Src activity during cell polarization. Molecular and cellular biology. 29:1933-1943.
  15. Huot, M.E., G. Vogel, and S. Richard. 2009. Identification of a Sam68 ribonucleoprotein complex regulated by epidermal growth factor. The Journal of biological chemistry. 284:31903-31913.
  16. Jani, K., and F. Schock. 2009. Molecular mechanisms of mechanosensing in muscle development. Developmental dynamics : an official publication of the American Association of Anatomists. 238:1526-1534.
  17. Jaramillo, M., M.J. Bellemare, C. Martel, M.T. Shio, A.P. Contreras, M. Godbout, M. Roger, E. Gaudreault, J. Gosselin, D.S. Bohle, and M. Olivier. 2009. Synthetic Plasmodium-like hemozoin activates the immune response: a morphology - function study. PloS one. 4:e6957.
  18. Javeshghani, D., E.L. Schiffrin, M.R. Sairam, and R.M. Touyz. 2009. Potentiation of vascular oxidative stress and nitric oxide-mediated endothelial dysfunction by high-fat diet in a mouse model of estrogen deficiency and hyperandrogenemia. Journal of the American Society of Hypertension : JASH. 3:295-305.
  19. Jeong, S.Y., K.I. Rathore, K. Schulz, P. Ponka, P. Arosio, and S. David. 2009. Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29:610-619.
  20. Katoh, Y., B. Ritter, T. Gaffry, F. Blondeau, S. Honing, and P.S. McPherson. 2009. The clavesin family, neuron-specific lipid- and clathrin-binding Sec14 proteins regulating lysosomal morphology. The Journal of biological chemistry. 284:27646-27654.
  21. Kedinger, V., L. Sansregret, R. Harada, C. Vadnais, C. Cadieux, K. Fathers, M. Park, and A. Nepveu. 2009. p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludin. The Journal of biological chemistry. 284:27701-27711.
  22. Khatchadourian, A., K. Krumova, S. Boridy, A.T. Ngo, D. Maysinger, and G. Cosa. 2009. Molecular imaging of lipid peroxyl radicals in living cells with a BODIPY-alpha-tocopherol adduct. Biochemistry. 48:5658-5668.
  23. Khatchadourian, A., and D. Maysinger. 2009. Lipid droplets: their role in nanoparticle-induced oxidative stress. Molecular pharmaceutics. 6:1125-1137.
  24. Krishnaswamy, A., and E. Cooper. 2009. An activity-dependent retrograde signal induces the expression of the high-affinity choline transporter in cholinergic neurons. Neuron. 61:272-286.
  25. Lachance, J.F., M.F. Lomas, A. Eleiche, P.B. Kerr, and L.A. Nilson. 2009. Graded Egfr activity patterns the Drosophila eggshell independently of autocrine feedback. Development. 136:2893-2902.
  26. Larocque, D., G. Fragoso, J. Huang, W.E. Mushynski, M. Loignon, S. Richard, and G. Almazan. 2009. The QKI-6 and QKI-7 RNA binding proteins block proliferation and promote Schwann cell myelination. PloS one. 4:e5867.
  27. Lin, C.J., R. Sukarieh, and J. Pelletier. 2009. Silibinin inhibits translation initiation: implications for anticancer therapy. Molecular cancer therapeutics. 8:1606-1612.
  28. Livingstone, M., O. Larsson, R. Sukarieh, J. Pelletier, and N. Sonenberg. 2009. A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E. Chem Biol. 16:1240-1249.
  29. Marcotte, R., L. Zhou, H. Kim, C.D. Roskelly, and W.J. Muller. 2009. c-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential. Molecular and cellular biology. 29:5858-5871.
  30. Merino, C., J. Penney, M. Gonzalez, K. Tsurudome, M. Moujahidine, M.B. O'Connor, E.M. Verheyen, and P. Haghighi. 2009. Nemo kinase interacts with Mad to coordinate synaptic growth at the Drosophila neuromuscular junction. The Journal of cell biology. 185:713-725.
  31. Michoud, M.C., R. Robert, M. Hassan, B. Moynihan, C. Haston, V. Govindaraju, P. Ferraro, J.W. Hanrahan, and J.G. Martin. 2009. Role of the cystic fibrosis transmembrane conductance channel in human airway smooth muscle. Am J Respir Cell Mol Biol. 40:217-222.
  32. Nguyen, A.H., M. Beland, Y. Gaitan, and M. Bouchard. 2009. Calcineurin a-binding protein, a novel modulator of the calcineurin-nuclear factor of activated T-cell signaling pathway, is overexpressed in wilms' tumors and promotes cell migration. Molecular cancer research : MCR. 7:821-831.
  33. Palijan, A., I. Fernandes, Y. Bastien, L. Tang, M. Verway, M. Kourelis, L.E. Tavera-Mendoza, Z. Li, V. Bourdeau, S. Mader, X.J. Yang, and J.H. White. 2009. Function of histone deacetylase 6 as a cofactor of nuclear receptor coregulator LCoR. The Journal of biological chemistry. 284:30264-30274.
  34. Palijan, A., I. Fernandes, M. Verway, M. Kourelis, Y. Bastien, L.E. Tavera-Mendoza, A. Sacheli, V. Bourdeau, S. Mader, and J.H. White. 2009. Ligand-dependent corepressor LCoR is an attenuator of progesterone-regulated gene expression. The Journal of biological chemistry. 284:30275-30287.
  35. Paliouras, G.N., M.A. Naujokas, and M. Park. 2009. Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. Molecular and cellular biology. 29:3018-3032.
  36. Ponzo, M.G., R. Lesurf, S. Petkiewicz, F.P. O'Malley, D. Pinnaduwage, I.L. Andrulis, S.B. Bull, N. Chughtai, D. Zuo, M. Souleimanova, D. Germain, A. Omeroglu, R.D. Cardiff, M. Hallett, and M. Park. 2009. Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 106:12903-12908.
  37. Shen, Z., N. Paquin, A. Forget, and P. Chartrand. 2009. Nuclear shuttling of She2p couples ASH1 mRNA localization to its translational repression by recruiting Loc1p and Puf6p. Molecular biology of the cell. 20:2265-2275.
  38. Sparrow, J.C., and F. Schock. 2009. The initial steps of myofibril assembly: integrins pave the way. Nature reviews. Molecular cell biology. 10:293-298.
  39. Sukarieh, R., N. Sonenberg, and J. Pelletier. 2009. The eIF4E-binding proteins are modifiers of cytoplasmic eIF4E relocalization during the heat shock response. American journal of physiology. Cell physiology. 296:C1207-1217.
  40. Thomas, S., B. Ritter, D. Verbich, C. Sanson, L. Bourbonniere, R.A. McKinney, and P.S. McPherson. 2009. Intersectin regulates dendritic spine development and somatodendritic endocytosis but not synaptic vesicle recycling in hippocampal neurons. The Journal of biological chemistry. 284:12410-12419.
  41. Tong, X.K., N. Nicolakakis, P. Fernandes, B. Ongali, J. Brouillette, R. Quirion, and E. Hamel. 2009. Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice. Neurobiology of disease. 35:406-414.
  42. Zoubeidi, A., J. Rocha, F.Z. Zouanat, L. Hamel, E. Scarlata, A.G. Aprikian, and S. Chevalier. 2009. The Fer tyrosine kinase cooperates with interleukin-6 to activate signal transducer and activator of transcription 3 and promote human prostate cancer cell growth. Molecular cancer research : MCR. 7:142-155.

 

2008

  1. Brown, C. M., R. B. Dalal, et al. 2008. Raster image correlation spectroscopy (RICS) for measuring fast protein dynamics and concentrations with a commercial laser scanning confocal microscope. J Microsc 229(Pt 1): 78-91.
  2. Dansereau, D.A., and P. Lasko. 2008. RanBPM regulates cell shape, arrangement, and capacity of the female germline stem cell niche in Drosophila melanogaster. The Journal of cell biology. 182:963-977.
  3. Digman, M. A., C. M. Brown, et al. 2008. Paxillin dynamics measured during adhesion assembly and disassembly by correlation spectroscopy. Biophys J 94(7): 2819-2831.
  4. Easley, C. A. t., C. M. Brown, et al. 2008. CaMK-II promotes focal adhesion turnover and cell motility by inducing tyrosine dephosphorylation of FAK and paxillin. Cell Motil Cytoskeleton 65(8): 662-674.
  5. Frigault, M.M., M.A. Naujokas, and M. Park. 2008. Gab2 requires membrane targeting and the Met binding motif to promote lamellipodia, cell scatter, and epithelial morphogenesis downstream from the Met receptor. J Cell Physiol. 214:694-705.
  6. Halle, M., M.A. Gomez, M. Stuible, H. Shimizu, W.R. McMaster, M. Olivier, and M.L. Tremblay. 2008. The Leishmania surface protease GP63 cleaves multiple intracellular proteins and actively participates in p38 mitogen activated protein kinase inactivation. The Journal of biological chemistry.
  7. Houssier, M., W. Raoul, S. Lavalette, N. Keller, X. Guillonneau, B. Baragatti, L. Jonet, J.C. Jeanny, F. Behar-Cohen, F. Coceani, D. Scherman, P. Lachapelle, H. Ong, S. Chemtob, and F. Sennlaub. 2008. CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents. PLoS Med. 5:e39.
  8. Khila, A., and E. Abouheif. 2008. Reproductive constraint is a developmental mechanism that maintains social harmony in advanced ant societies. Proc Natl Acad Sci U S A. 105:17884-17889.
  9. Kodiha, M., P. Banski, D. Ho-Wo-Cheong, and U. Stochaj. 2008. Dissection of the molecular mechanisms that control the nuclear accumulation of transport factors importin-alpha and CAS in stressed cells. Cell Mol Life Sci. 65:1756-1767.
  10. Kodiha, M., C.M. Brown, and U. Stochaj. 2008. Analysis of signaling events by combining high-throughput screening technology with computer-based image analysis. Sci Signal. 1:pl2.
  11. Kodiha, M., D. Tran, C. Qian, A. Morogan, J.F. Presley, C.M. Brown, and U. Stochaj. 2008. Oxidative stress mislocalizes and retains transport factor importin-alpha and nucleoporins Nup153 and Nup88 in nuclei where they generate high molecular mass complexes. Biochim Biophys Acta. 1783:405-418.
  12. Lee, S., L. Zhou, J. Kim, S. Kalbfleisch, and F. Schock. 2008. Lasp anchors the Drosophila male stem cell niche and mediates spermatid individualization. Mechanisms of development. 125:768-776.
  13. Ouellet, J., S. Li, and R. Roy. 2008. Notch signalling is required for both dauer maintenance and recovery in C. elegans. Development. 135:2583-2592.
  14. Sangwan, V., G.N. Paliouras, J.V. Abella, N. Dube, A. Monast, M.L. Tremblay, and M. Park. 2008. Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase. The Journal of biological chemistry. 283:34374-34383.
  15. Ursini-Siegel, J., W.R. Hardy, D. Zuo, S.H. Lam, V. Sanguin-Gendreau, R.D. Cardiff, T. Pawson, and W.J. Muller. 2008. ShcA signalling is essential for tumour progression in mouse models of human breast cancer. Embo J.
  16. Zaun, H.C., A. Shrier, and J. Orlowski. 2008. Calcineurin B homologous protein 3 promotes the biosynthetic maturation, cell surface stability, and optimal transport of the Na+/H+ exchanger NHE1 isoform. The Journal of biological chemistry. 283:12456-12467.

 

2007

  1. Brault, S., F. Gobeil, Jr., A. Fortier, J.C. Honore, J.S. Joyal, P.S. Sapieha, A. Kooli, E. Martin, P. Hardy, A. Ribeiro-da-Silva, K. Peri, P. Lachapelle, D. Varma, and S. Chemtob. 2007. Lysophosphatidic acid induces endothelial cell death by modulating the redox environment. Am J Physiol Regul Integr Comp Physiol. 292:R1174-1183.
  2. Brown, C.M. 2007. Fluorescence microscopy--avoiding the pitfalls. Journal of cell science. 120:1703-1705.
  3. Dillon, R.L., S.T. Brown, C. Ling, T. Shioda, and W.J. Muller. 2007. An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer. Molecular and cellular biology. 27:8648-8657.
  4. Jani, K., and F. Schock. 2007. Zasp is required for the assembly of functional integrin adhesion sites. The Journal of cell biology. 179:1583-1597.
  5. Kodiha, M., J.G. Rassi, C.M. Brown, and U. Stochaj. 2007. Localization of AMP kinase is regulated by stress, cell density, and signaling through the MEK-->ERK1/2 pathway. American journal of physiology. Cell physiology. 293:C1427-1436.
  6. Lahlou, H., V. Sanguin-Gendreau, D. Zuo, R.D. Cardiff, G.W. McLean, M.C. Frame, and W.J. Muller. 2007. Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression. Proc Natl Acad Sci U S A. 104:20302-20307.
  7. Mak, H.H., P. Peschard, T. Lin, M.A. Naujokas, D. Zuo, and M. Park. 2007. Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway. Oncogene. 26:7213-7221.
  8. Sheftel, A.D., A.S. Zhang, C. Brown, O.S. Shirihai, and P. Ponka. 2007. Direct interorganellar transfer of iron from endosome to mitochondrion. Blood. 110:125-132.
  9. Ursini-Siegel, J., A.B. Rajput, H. Lu, V. Sanguin-Gendreau, D. Zuo, V. Papavasiliou, C. Lavoie, J. Turpin, K. Cianflone, D.G. Huntsman, and W.J. Muller. 2007. Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development. Molecular and cellular biology. 27:6361-6371.
  10. Walker, V.E., R. Atanasiu, H. Lam, and A. Shrier. 2007. Co-chaperone FKBP38 promotes HERG trafficking. The Journal of biological chemistry. 282:23509-23516.

 

2006

  1. Bates, I.R., B. Hebert, Y. Luo, J. Liao, A.I. Bachir, D.L. Kolin, P.W. Wiseman, and J.W. Hanrahan. 2006. Membrane lateral diffusion and capture of CFTR within transient confinement zones. Biophysical journal. 91:1046-1058.
  2. Bates, I.R., P.W. Wiseman, and J.W. Hanrahan. 2006. Investigating membrane protein dynamics in living cells. Biochem Cell Biol. 84:825-831.
  3. Cho, P.F., C. Gamberi, Y.A. Cho-Park, I.B. Cho-Park, P. Lasko, and N. Sonenberg. 2006. Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos. Current biology : CB. 16:2035-2041.
  4. Grote, D., A. Souabni, M. Busslinger, and M. Bouchard. 2006. Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney. Development. 133:53-61.
  5. Han, W., S. Nattel, T. Noguchi, and A. Shrier. 2006. C-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2. The Journal of biological chemistry. 281:27134-27144.
  6. Silvius, J.R., P. Bhagatji, R. Leventis, and D. Terrone. 2006. K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes. Molecular biology of the cell. 17:192-202.

 

2005

  1. Abella, J.V., P. Peschard, M.A. Naujokas, T. Lin, C. Saucier, S. Urbe, and M. Park. 2005. Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation. Molecular and cellular biology. 25:9632-9645.
  2. Benlimame, N., Q. He, S. Jie, D. Xiao, Y.J. Xu, M. Loignon, D.D. Schlaepfer, and M.A. Alaoui-Jamali. 2005. FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion. The Journal of cell biology. 171:505-516.
  3. Caceres, L., and L.A. Nilson. 2005. Production of gurken in the nurse cells is sufficient for axis determination in the Drosophila oocyte. Development. 132:2345-2353.
  4. Imaizumi, K., and G.S. Pollack. 2005. Central projections of auditory receptor neurons of crickets. J Comp Neurol. 493:439-447.
  5. Johnstone, O., R. Deuring, R. Bock, P. Linder, M.T. Fuller, and P. Lasko. 2005. Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Developmental biology. 277:92-101.
  6. Khoury, H., M.A. Naujokas, D. Zuo, V. Sangwan, M.M. Frigault, S. Petkiewicz, D.L. Dankort, W.J. Muller, and M. Park. 2005. HGF converts ErbB2/Neu epithelial morphogenesis to cell invasion. Molecular biology of the cell. 16:550-561.
  7. Kim, H., R. Chan, D.L. Dankort, D. Zuo, M. Najoukas, M. Park, and W.J. Muller. 2005. The c-Src tyrosine kinase associates with the catalytic domain of ErbB-2: implications for ErbB-2 mediated signaling and transformation. Oncogene. 24:7599-7607.
  8. Long, J., D. Zuo, and M. Park. 2005. Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin. The Journal of biological chemistry. 280:35477-35489.
  9. Rodrigues, S.P., K.E. Fathers, G. Chan, D. Zuo, F. Halwani, S. Meterissian, and M. Park. 2005. CrkI and CrkII function as key signaling integrators for migration and invasion of cancer cells. Mol Cancer Res. 3:183-194.
  10. Szabo, E.Z., M. Numata, V. Lukashova, P. Iannuzzi, and J. Orlowski. 2005. beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform. Proc Natl Acad Sci U S A. 102:2790-2795.
  11. Wang, T.Y., R. Leventis, and J.R. Silvius. 2005. Artificially lipid-anchored proteins can elicit clustering-induced intracellular signaling events in Jurkat T-lymphocytes independent of lipid raft association. The Journal of biological chemistry. 280:22839-22846.

 

2004

  1. Chan, R., W.R. Hardy, D. Dankort, M.A. Laing, and W.J. Muller. 2004. Modulation of Erbb2 signaling during development: a threshold level of Erbb2 signaling is required for development. Development. 131:5551-5560.
  2. Johnstone, O., and P. Lasko. 2004. Interaction with eIF5B is essential for Vasa function during development. Development. 131:4167-4178.
  3. Reed, B.H., R. Wilk, F. Schock, and H.D. Lipshitz. 2004. Integrin-dependent apposition of Drosophila extraembryonic membranes promotes morphogenesis and prevents anoikis. Current biology : CB. 14:372-380.
  4. Thomson, T., and P. Lasko. 2004. Drosophila tudor is essential for polar granule assembly and pole cell specification, but not for posterior patterning. Genesis. 40:164-170.
  5. White, D.E., N.A. Kurpios, D. Zuo, J.A. Hassell, S. Blaess, U. Mueller, and W.J. Muller. 2004. Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell. 6:159-170.

 

2003

  1. Fournes, B., J. Farrah, M. Olson, N. Lamarche-Vane, and N. Beauchemin. 2003. Distinct Rho GTPase activities regulate epithelial cell localization of the adhesion molecule CEACAM1: involvement of the CEACAM1 transmembrane domain. Molecular and cellular biology. 23:7291-7304.
  2. Schock, F., and N. Perrimon. 2003. Retraction of the Drosophila germ band requires cell-matrix interaction. Genes & development. 17:597-602.
  3. Treichel, D., F. Schock, H. Jackle, P. Gruss, and A. Mansouri. 2003. mBtd is required to maintain signaling during murine limb development. Genes & development. 17:2630-2635.