Elias Georges - Publications

Fallatah O and Georges E (2017) Apigenin-induced ABCC1-mediated efflux of glutathione from mature erythrocytes inhibits the proliferation of Plasmodium falciparum. Int J Antimicrob Agents 50: 673-677.

Ambadipudi R and Georges E (2017) Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation. Biochem Biophys Res Commun 482: 1001-1006.

Edaye S, Tazoo D, Bohle DS and Georges E (2016) 3-Iodo-4-aminoquinoline derivative sensitises resistant strains of Plasmodium falciparum to chloroquine. Int J Antimicrob Agents 47: 482-5.

Edaye S, Tazoo D, Bohle DS and Georges E (2015) 3-Halo Chloroquine Derivatives Overcome Plasmodium falciparum Chloroquine Resistance Transporter-Mediated Drug Resistance in P. falciparum. Antimicrob Agents Chemother 59: 7891-3.

Edaye S and Georges E (2015) Characterization of native PfABCG protein in Plasmodium falciparum. Biochem Pharmacol 97: 137-46.

Laberge RM, Ambadipudi R and Georges E (2014) P-glycoprotein mediates the collateral sensitivity of multidrug resistant cells to steroid hormones. Biochem Biophys Res Commun 447: 574-9.

Georges E, Lian J and Laberge R (2014) A tamoxifen derivative, N,N-diethyl-2-[4-(phenylmethyl) phenoxy] ethanamine, selectively targets P-glycoprotein-positive multidrug resistant Chinese hamster cells. Biochem Pharmacol 90: 107-14.

Edaye S, Reiling SJ, Leimanis ML, Wunderlich J, Rohrbach P and Georges E (2014) A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctan oic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum. Mol Biochem Parasitol 195: 34-42.

Edaye S and Georges E (2014) Expression and subcellular localization of the oly member of ABCG subfamily in Plasmodium falciparum. Molecular and Biochemical Parasitology In Press:

Laberge RM, Ambadipudi R and Georges E (2014) P-glycoprotein mediates the collateral sensitivity of multidrug resistant cells to steroid hormones. Biochem Biophys Res Commun 447: 574-9.

Georges E, Lian J and Laberge R (2014) A tamoxifen derivative, N,N-diethyl-2-[4-(phenylmethyl) phenoxy] ethanamine, selectively targets P-glycoprotein-positive multidrug resistant Chinese hamster cells. Biochem Pharmacol 90: 107-14.

Edaye S, Reiling SJ, Leimanis ML, Wunderlich J, Rohrbach P and Georges E (2014) A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctan oic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum. Mol Biochem Parasitol 195: 34-42.

Tripathy U, Giguere-Bisson M, Sangji MH, et al. (2013) Optimization of malaria detection based on third harmonic generation imaging of hemozoin. Anal Bioanal Chem 405: 5431-40.

Yang Y, Li Z, Mo W, et al. (2012) Human ABCC1 interacts and colocalizes with ATP synthase alpha, revealed by interactive proteomics analysis. J Proteome Res 11: 1364-72.

Prinos P, Lacoste MC, Wong J, Bonneau AM and Georges E (2011) Mutation of cysteine 21 inhibits nucleophosmin/B23 oligomerization and chaperone activity. Int J Biochem Mol Biol 2: 24-30.

Leimanis ML, Karwatsky J and Georges E (2011) Photoaffinity labeling of the multidrug resistance protein 2 (ABCC2/cMOAT) with a photoreactive analog of LTC(4). Int J Biochem Mol Biol 2: 39-46.

Georges E, Bonneau AM and Prinos P (2011) RNAi-mediated knockdown of alpha-enolase increases the sensitivity of tumor cells to antitubulin chemotherapeutics. Int J Biochem Mol Biol 2: 303-8.

Laberge RM, Ambadipudi R and Georges E (2009) P-glycoprotein (ABCB1) modulates collateral sensitivity of a multidrug resistant cell line to verapamil. Arch Biochem Biophys 491: 53-60.

Bellemare MJ, Bohle DS, Brosseau CN, et al. (2009) Autofluorescence of condensed heme aggregates in malaria pigment and its synthetic equivalent hematin anhydride (beta-hematin). J Phys Chem B 113: 8391-401.

Belisle JM, Costantino S, Leimanis ML, et al. (2008) Sensitive detection of malaria infection by third harmonic generation imaging. Biophys J 94: L26-8.