Derek Bowie

Title: 
Full Professor
Derek Bowie
Contact Information
Email address: 
derek.bowie [at] mcgill.ca
Phone: 
514-398-1581
514-398-2513
Department: 
Department of Pharmacology and Therapeutics
MNI - Department of Neurology and Neurosurgery
Fields: 
Diseases/Disorders
Pharmacology
Vision
Areas of expertise: 

The Bowie Lab uses a combination of techniques to study ionotropic glutamate receptors (iGluRs), GABA-A receptors and more recently, Na+ channels. All ion-channel families are widespread in the vertebrate brain and fulfill many important roles in healthy individuals as well as being implicated in disease states associated with postnatal development (e.g. Autism, Schizophrenia), cerebral insult (e.g. Stroke, Epilepsy) and aging disorders (e.g. Alzheimer's disease, Parkinsonism). We are looking at iGluRs, GABA-A receptors and Na+ channels at two inter-related levels. In molecular terms, we are examining the events that occur when each ion-channel family is activated with the aim of developing novel therapeutic compounds. At the cellular level, we are studying the role that iGluRs, GABA-A receptors and Na+ channels fulfill in shaping the behaviour of neuronal circuits and how these processes may be corrected in disease states.

Language(s) spoken: 
English
French
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