Canada Research Chair in Humoral Immunity
The focus of our research is to understand how immune cells communicate with their local environment to promote protective immune responses relevant to human disease. We are particularly interested in immunity at barrier sites such as the gut, skin and lung as these tissues face the complex task of maintaining homeostasis while directly interacting with the outside world. Ongoing studies including:
- The molecular mechanisms of CD4+ T cell differentiation following intestinal helminth infection.
- Innate immune responses that initiate and/or regulate Type 2 immune responses following intestinal helminth and bacterial infection.
- Regulation of skin-resident IL-17-producing T cells in the context of psoriatic-like inflammation.
- The influence of the microbiota on protective immunity at barrier sites.