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Recruitment Offer for Master’s and PhD Students-University of Sherbrooke
Pre-requisite: Bioinformatics Training Research Context Antimicrobial resistance (AMR) represents one of the critical challenges for public health. According to the World Health Organization, Acinetobacter baumannii represents one of the priority bacteria for research and development. Knowledge about this bacteria and the evolution of its antibiotic resistance profile remain limited in many parts of the world, notably in the Middle East. Our team has gathered a unique collection of over 1,200 isolates of A. baumannii from the Middle East dating back to the late 1990’s. The entire collection has undergone whole genome sequencing (WGS).
Objectives Based on data obtained from WGS:
1) establish a profile of A. baumannii isolates present in the Middle East since the 1990’s (MLST, AMR genes, phylogeny …);
2) participate with the principal investigator and a PhD student in Anthropology in correlating results of our analyses in point 1) with socio-historical data (antibiotic use, timing and location of armed conflicts, environmental toxicity …).
Results from this research will enable:
a) to enrich our understanding of the emergence and spread of antibiotic-resistant isolates of A. baumannii;
b) to identify unsuspected risk factors contributing to AMR in order to better guide interventions to limit its impacts;
c) to validate the advantages of an interdisciplinary bio-historical methodology.
This project is financed by the New Frontiers in Research Fund of Canada (250K$). Selected students are highly encouraged to submit applications for training awards to funding agencies. Bursaries are available depending on student profiles.
Contact: Louis-Patrick Haraoui, MD, MSc, FRCPC, Assistant Professor, Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, louis.patrick.haraoui [at] usherbrooke.ca