Scientists from the Montreal Neurological Institute and Hospital in Canada have discovered that two genes linked to hereditary Parkinson’s disease are involved in the early-stage quality control of mitochondria. The protective mechanism, which is reported in The EMBO Journal, removes damaged proteins that arise from oxidative stress from mitochondria.
Speaker: Yang Dan, PhD,
Howard Hughes Investigator,
Professor of Neurobiology,
University of California, Berkeley
Images of The Neuro is literary eyewitness to medical history
In a new collection of insightful essays and selected photos, one of Canada’s most eminent medical figures, Dr. William Feindel, shines a personal light on the world-famous institution that he headed for 12 years, the Montreal Neurological Institute and Hospital – The Neuro, McGill University, as well as on some giants of medicine like Osler, Willis, Gilbert and Penfield.
Merck Canada announced yesterday the allocation of a total of $16 million in grants to Quebec’s four faculties of medicine. McGill, along with Université de Montréal, Université de Sherbrooke and Université Laval will each receive $4 M to support health research with a translational component conducted in areas of unmet medical need. The announcement was made in Quebec City at the BioContact Quebec Biopharmaceutical Partnership Symposium, in the presence of Dr. Thomas R. Cannell, President and Managing Director, Merck Canada Inc., and of Pierre Duchesne, Minister of Higher Education, Research, Science and Technology.
Researchers at McGill University have found that sodium – the main chemical component in table salt – is a unique “on/off” switch for a major neurotransmitter receptor in the brain. This receptor, known as the kainate receptor, is fundamental for normal brain function and is implicated in numerous diseases, such as epilepsy and neuropathic pain.
A new network that is bringing together expertise from universities, government and industry is implementing a new vision for training the next generation of medical physicists. Ultrasounds, X-rays, MRIs and nuclear medicine are only a few examples of the essential contributions of medical physicists. The field of medical physics applies the principles of physics to medicine, from diagnosis to treatment, and seeks to quickly transform scientific discovery into clinical applications. Medical physicists are also clinical health care professionals providing service in fields such as radiation therapy, medical imaging, nuclear medicine or radiation protection, to name a few.
Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing to a disease is only a first step. To apply this knowledge towards prevention or cure, including tailoring treatment to the patient’s genetic profile –also known as personalized medicine – we need to know how this genetic variant affects health.
Researchers at McGill University have discovered a new way to join materials together using ultrasound. Ultrasound – sound so high it cannot be heard – is normally used to smash particles apart in water. In a recent study, the team of researchers, led by McGill professor Jake Barralet, from the faculties of Dentistry and Medicine, found that if particles were coated with phosphate, they could instead bond together into strong agglomerates, about the size of grains of sand. Their results are published in the journal Advanced Materials.
Only 11% of drugs that enter clinical trials in humans are ultimately found safe and effective enough to receive regulatory approval.
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TELUS Health and McGill University have entered into a three-year, million dollar partnership to create a learning environment and conduct research on how best to use technology to improve health and healthcare delivery for Canadians. This joint partnership with McGill is the second for TELUS Health, demonstrating once again that industry and academic communities can collaborate to produce independent, evidence-based research, in order to help address challenges that the Canadian healthcare system is facing.