Research Published in Collaboration with other Researchers

1. Hosokawa, N., Tremblay, L. O., Sleno, B., Kamiya, Y., Wada, I., Nagata, K., Kato, K., Herscovics, A. (2010) EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans, Glycobiology 20, 567-575

2. Volpato, J. P., Yachnin, B. J., Blanchet, J., Guerrero, V., Poulin, L., Fossati, E., Berghuis, A. M., Pelletier, J. N. (2009) Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance, J Biol Chem 284, 20079-20089.

3. Xiong, B., Burk, D. L., Shen, J., Luo, X., Liu, H., Shen, J., Berghuis, A. M. (2008) The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation, Proteins 71, 1984-1994.

4. Miller, W. L., Matewish, M. J., McNally, D. J., Ishiyama, N., Anderson, E. M., Brewer, D., Brisson, J. R., Berghuis, A., and Lam, J. S. (2008) Flagellin glycosylation in Pseudomonas aeruginosa PAK requires the O-antigen biosynthesis enzyme WbpO, J Biol Chem 283, 3507-3518.

5. Peschard, P., Kozlov, G., Lin, T., Mirza, I. A., Berghuis, A., Lipkowitz, S., Park, M., and Gehring, K. (2007) Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b, Molecular Cell 27, 474-485.

6. Nascimento, M., Zhang, W. W., Ghosh, A., Houston, D. R., Berghuis, A., Olivier, M., and Matlashewski, G. (2006) Identification and characterization of a protein-tyrosine phosphatase in Leishmania: Involvement in virulence, J Biol Chem 281, 36257-36268.

7. Gao, F., Yan, X., Shakya, T., Baettig, O., Ait-Mohand-Brunet, S., Berghuis, A., Wright, G. D., and Auclair, K. (2006) Synthesis and structure-activity relationships of truncated bisubstrate inhibitors of aminoglycoside 6'-N-acetyltransferases, J Med Chem 49, 5273-5281.

8. Demendi, M., Ishiyama, N., Lam, J. S., Berghuis, A., and Creuzenet, C. (2005) Towards a better understanding of the substrate specificity of the UDP-N-acetylglucosamine C4 epimerase WbpP, Biochem J 389, 173-180.

9. Christensen, K. E., Mirza, I. A., Berghuis, A., and Mackenzie, R. E. (2005) Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase, J Biol Chem 280, 34316-34323.

10. Bernatchez, S., Szymanski, C. M., Ishiyama, N., Li, J., Jarrell, H. C., Lau, P. C., Berghuis, A., Young, N. M., and Wakarchuk, W. W. (2005) A single bifunctional UDP-GlcNAc/Glc 4-epimerase supports the synthesis of three cell surface glycoconjugates in Campylobacter jejuni, J Biol Chem 280, 4792-4802.

11. Daigle, D. M., Rossi, L., Berghuis, A., Aravind, L., Koonin, E. V., and Brown, E. D. (2002) YjeQ, an essential, conserved, uncharacterized protein from Escherichia co li, is an unusual GTPase with circularly permuted G-motifs and marked burst kinetics, Biochemistry 41, 11109-11117.

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