UAlberta and McGill scientists uncover a hidden calcium cholesterol connection
By Ross Neitz, University of Alberta
It’s well known that calcium is essential for strong bones and teeth, but new research shows it also plays a key role in moderating another important aspect of health—cholesterol.
Scientists at the University of Alberta and McGill University have discovered a direct link between calcium and cholesterol, a discovery that could pave the way for new ways of treating high blood cholesterol.
Diabetes drug may help symptoms of autism-associated condition
Metformin, the most widely used drug to treat type 2 diabetes, could potentially be used to treat symptoms of Fragile X syndrome, an inherited form of intellectual disability and a cause of some forms of autism.
A new study led by researchers at McGill University, the University of Edinburgh and Université de Montréal has found that metformin improves social, behavioural and morphological defects in Fragile X mice.
Solving medical “cold cases” through genetics
Researchers have identified the genetic mutation responsible for one patient's serious health problems, finally solving a medical mystery that has endured for over 30 years.
Encouraging results for patients with aggressive brain cancer
Being diagnosed with a malignant brain tumor is devastating news for patients and their loved ones. Whereas some types of tumor respond well to treatment, others such as glioblastomas – the most common and aggressive brain tumors – are known to recur and progress within short times from the diagnosis. Patients diagnosed with this type of cancer, and who undergo current standard treatment, have a median survival of 16 months.
Woodstoves are good for the soul, bad for the heart
The risk of acute myocardial infarction for the elderly living in and around small cities is increased by air pollution caused by biomass burning from woodstoves.
It is well documented that air pollution in big cities causes heart and lung problems. But what are its consequences on people in smaller urban centres?
Targeting the biological clock could slow the progression of cancer
Does the biological clock in cancer cells influence tumour growth? Yes, according to a study conducted by Nicolas Cermakian, a professor in McGill University’s Department of Psychiatry.
Published in the journal BMC Biology, these results show for the first time that directly targeting the biological clock in a cancerous tumour has an impact on its development.
Breakthrough in MS treatment
In separate clinical trials, a drug called ocrelizumab has been shown to reduce new attacks in patients with relapsing remitting multiple sclerosis (MS), and new symptom progression in primary progressive MS.
Lottery tickets aren’t child’s play
Lottery tickets may be fun-filled and exciting presents, but they are not suitable gifts for minors. Studies suggest that gambling is a popular yet risky activity among youth. Additionally, researchers have reported a correlation between age of gambling onset and problem gambling later in life. Lottery play is sometimes an initial introduction to gambling activities for minors.
Men have a lot to learn about their own fertility
The first large-scale study of its kind has revealed that Canadian men generally lack knowledge about the risk factors contributing to male infertility. Research led by Dr. Phyllis Zelkowitz, head of psychosocial research at the Lady Davis Institute of the Jewish General Hospital, found that men could only identify about 50% of the potential risks and medical conditions that are detrimental to their sperm count and, thus, their prospects to father children.
International Human Epigenome Consortium studies mark major step forward for epigenetics research
One of the great mysteries in biology is how the many different cell types that make up our bodies are derived from a single cell and from one DNA sequence, or genome. We have learned a lot from studying the human genome, but have only partially unveiled the processes underlying cell determination.
Researchers identify gene associated with intracranial aneurysm in French-Canadian population
Scientists have identified a gene in the French-Canadian population that predisposes them to the development of intracranial aneurysm (IA), a potentially life threatening neurological condition that is responsible for approximately 500,000 deaths worldwide per year, half of which occur in people less than 50 years of age.
Could quality of sleep have to do with sex differences?
You may have noticed that women are more prone to sleep disturbances than men. They are, for instance, up to twice as likely to suffer from insomnia than men. Could there be a link between the body clock that regulates sleep and being a female or a male? Yes, according to an original study conducted by Dr. Diane B. Boivin of McGill University’s Department of Psychiatry and the Douglas Mental Health University Institute.