Dr. Anne Gatignol

Academic title(s): 

Professor - Department of Medicine

Dr. Anne Gatignol
Contact Information
Address: 

Lady Davis Institute for Medical Research
Jewish General Hospital
3755 Côte Ste-Catherine Road,
Montreal, Qc, H3T 1E2

Phone: 
(514) 340-8260 ext. 25284
Email address: 
anne.gatignol [at] mcgill.ca
Current research: 

HIV

Projects: 

1. Using RNA-based technologies to target HIV RNA and RNA coding for cellular factors involved in HIV replication. The objective is to control viral replication for a use in gene therapy of HIV infection.
2. Elucidating HIV-induced modifications of the RNA interference (RNAi) pathway during viral replication. The objective is to analyze the changes in proteins of the RNAi pathway and in microRNA expression to explain HIV-associated pathologies.
3. Analyzing virus-host molecular interactions in the regulation of the innate cell response to HIV infection in lymphocytes, monocytes and astrocytes in relationship with viral persistence in HIV-infected patients.
4. Function of TRBP-Dicer-Ago2 interactions in RNA interference and cellular localization in mammalian cells.

Selected publications: 
Research areas: 
Immunology
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