Courses

May Session:

May 6 to May 31, 2019

(no classes Monday, May 20- Victoria Day)

EPIB 507 Biostatistics for Health Professionals

elham.rahme [at] mcgill.ca (Dr. E. Rahme)

Basic principles of statistical inference applicable to clinical, epidemiologic, and other health research. Topics include: methods of describing data, statistical inference for means, statistical inference for proportions, non-parametric statistics, correlation and introduction to linear regression.

Restriction: Restricted to students registered in Occupational Health, Dentistry, Rehabilitation Sciences, Human Nutrition, Experimental Medicine, Family Medicine, Otolaryngology, Medical Residents, and Clinical Fellows, or permission of the instructor.

Prerequisite: Permission of instructor for students not listed in the restrictions above.

NOTES: Medical Residents and Clinical Fellows can register for this course only during the Summer term.

Course not opened to students registered in the Epidemiology, Public Health or Biostatistics programs.

May 6 to May 31 - no classes Monday, May 20 (Victoria Day)
Monday/Wednesday/Friday
14h00 to 17h30
Education Building, RM 624
(CRN 858)

Academic Credits: 3

EPIB 600-001 Clinical Epidemiology

nitika.pai [at] mcgill.ca (Dr. N. Pai)

The general objective of this 3-credit course is to provide students with a basic understanding of the methods of epidemiology, as applied to clinical research. Issues to be addressed include measurement issues, study design, analysis, and inference in the clinical research setting. Students will have the opportunity to apply these concepts to their own areas of interest.

All students should have a strong clinical background in medicine or an allied health profession. Preference will be given to residents and fellows enrolled in postgraduate medical training programs at McGill University. Previous course work in epidemiology or research experience is not required.

May 6 to May 31 - no classes Monday, May 20 (Victoria Day)
Monday/Wednesday/Friday
09h00 to 12h30
Education Building, RM 627 (with the exception of May 22 and 24, course will be held in Education, RM 624)
CRN (859)

Academic credits: 3

EPIB-619: Systematic Reviews and Meta-analyses

richard.menzies [at] mcgill.ca (Dr. R. Menzies)

Systematic reviews, meta-analyses and individual patient data meta-analyses are critical for evidence-based clinical and public health practice. The widespread and growing application of systematic reviews to synthesize evidence on key research and clinical questions makes it useful for most health professionals to be able to understand and critique this research design, and, to undertake reviews themselves. This course will provide a detailed description of the systematic review process, discuss the strengths and limitations of the method, and provide step-by-step guidance on how to actually perform a systematic review. Specific topics to be covered (and emphasized through numerous examples from the medical literature) include: formulation of the review question, searching of literature, quality assessment of studies, data extraction, meta-analytic methods, and report writing, as well as individual patient data meta-analyses. The course will also cover statistical issues such as selection of a proper statistical model for meta-analysis, including problem sets with practical examples of fixed and random effects models as well as examples of methods to evaluate heterogeneity and publication bias; graphical and tabular templates for the presentation of data from a meta-analysis. Several software packages (such as SAS or STATA) will be discussed, along with tutorials on how to effectively use tools such as PubMed and EndNote for conducting systematic reviews.

Restriction: Registration is open to students in the Epidemiology, Biostatistics and Public Health programs, as well as Medical Residents. All other student must obtain permission from the instructor in order to register.

Prerequisites: Introductory level training in epidemiology and biostatistics.

May 6 to May 17
Monday to Friday
13h00 to 16h15
Location: TBA
(CRN 860)

Academic credits: 2

EPIB-643 Clinical Trials
Substantive Epidemiology 3

tom.koutsavlis [at] mcgill.ca (Dr. T. Koutsavlis)

This course is designed to provide an overview of issues and approaches to the design and analysis of randomized clinical trials. Topics to be considered include specification of a primary question, adherence to ethical guidelines, reasons for and means of implementing randomization, consideration of design alternatives, sample size determination, subject recruitment, analytic strategies and trial reporting. The course provides an alternative to students who are unable to pursue a more in depth treatment of clinical trials provided in the 3 credit course offered during the regular academic year.

May 9 to 30
Thursday
13h00 to 16h15
Purvis Hall, RM 48
(CRN 861)

Academic Credit: 1

EPIB-654 PE IV: Pharmacoeconomics

jaime.caro [at] mcgill.ca (Dr. J. Caro)

As prices for pharmaceuticals climb ever higher, the formal assessment of what is a reasonable price to pay for a given benefit has gained increasing attention. This course provides a detailed introduction to the key concepts of this field, including those providing the foundation for economic evaluation in Quebec, in Canada, and in various European countries. After defining the basic economic problem, study types (cost-benefit, cost-utility, cost-effectiveness) and corresponding decision rules are examined. An example is constructed in detail to demonstrate how models are developed and a new approach to simulation, known as DICE and developed by the instructor, will be presented. Students are shown how costs and effectiveness are estimated – and how to analyze the model, including how to deal with all levels of uncertainty. The course presents techniques for presentation of results to decision makers in the public and private health care systems, including the efficiency frontier approach.

Prerequisites: Permission of instructor

May 27 to May 30
Monday to Thursday
09h00 to 17h00
Purvis Hall, RM 24
(CRN 862)

Academic Credits: 2

EPIB-671 Cancer Epidemiology and Prevention

eduardo.franco [at] mcgill.ca (Dr. E.L. Franco)

The course will explore the common epidemiologic approaches to studying etiologic relations in carcinogenesis and for assessing the efficacy of cancer prevention interventions. Emphasis will be given on both molecular and social epidemiology domains with examples of different study designs and data analysis methods and of the impact of measurement error and other biases.

Prerequisite: EPIB-601 or equivalent or permission of the instructor.

May 6 to May 24 - no classes Monday, May 20 (Victoria Day)
Monday/Wednesday/Friday + Tuesday, May 21 (make up class for Victoria Day)
13h00 to 17h00
Gerald Bronfman Department of Oncology
McGill University
5100 Maisonneuve Blvd. West, 7th Floor
RM 740A
Montreal, QC, H4A 3T2
(CRN 863)

Academic Credit: 3

June Session:

June 4 to June 29, 2018

(no classes Monday, June 24 - St-Jean-Baptiste)

EPIB 600-002 Clinical Epidemiology

maida.sewitch [at] mcgill.ca (Dr. M. Sewitch) / Dr. I. Fortier

The general objective of this 3-credit course is to provide students with a basic understanding of the methods of epidemiology, as applied to clinical research. Issues to be addressed include measurement issues, study design, analysis, and inference in the clinical research setting. Students will have the opportunity to apply these concepts to their own areas of interest.

All students should have a strong clinical background in medicine or an allied health profession. Preference will be given to residents and fellows enrolled in postgraduate medical training programs at McGill University. Previous course work in epidemiology or research experience is not required.

June 3 to June 28
Monday/Wednesday/Friday
09h00 to 12h30
Location: TBA
(CRN 864)

Academic credits: 3

EPIB-633 PE I: Introduction to Pharmacoepidemiology

christel.renoux [at] mcgill.ca (Dr. C. Renoux)
Guest lecturer: L. Levesque

This course is designed to introduce concepts and principles of pharmacoepidemiology in the context of drug evaluation and therapeutic decision-making. Topics to be covered include history of pharmacoepidemiology, choice of study design, sources of bias and their prevention and control, the importance of prescribing and drug taking behaviours, sources and use of exposure and outcome data, assessing causality, and measures of association. Examples will be drawn from published pharmacoepidemiologic studies. Participants will have an opportunity to design and critique a study that addresses a current therapeutic controversy.

Prerequisites: Permission of instructor

June 3 to June 6
Monday to Thursday
09h00 to 17h00
Purvis Hall, RM 25
(CRN 865)

Academic Credits: 2

EPIB-631 PE II: Intermediate Pharmacoepidemiology

laurent.azoulay [at] mcgill.ca (Dr. L. Azoulay) / kristian.filion [at] mcgill.ca (K. Filion)

The objective of this course is to build on the principles covered in Introduction to Pharmacoepidemiology and provide students with a more advanced understanding of the design and analysis of pharmacoepidemiological studies. This course addresses both methodological and practical issues in pharmacoepidemiology through didactic lectures, group discussions, and the examination of examples from the medical literature. Topics covered include themes related to the exposure time windows, the use of active drug comparators, latency and the application of lag periods, reverse causality, detection bias, methodological considerations in the assessment of acute versus insidious outcomes, new-user designs, healthy-user effects, and non-traditional study designs. In addition, the role of confounding and methods used to minimize its effects, such as propensity scores, are discussed in detail. Other special topics include meta-analyses of pharmacoepidemiologic studies.

Prerequisites: EPIB 633 or Permission of instructor

June 11 to 14
Tuesday to Friday
09h00 to 17h00
Purvis Hall, RM 25
(CRN 866)

Academic Credits: 2

EPIB-636 Reproductive Epidemiology

olga.basso [at] mcgill.ca (Dr. O. Basso)

This course will provide an overview of reproductive epidemiology, as well as introduce basic concepts and principles for this area of research. The focus will be on methodological issues related to studying repeated pregnancy outcomes, infertility, fetal loss, neonatal mortality, birth weight and gestational age. The course will also provide students with tools for critical reading of scientific articles in this field.

Prerequisites: Basic knowledge of epidemiology is highly recommended.

June 3 to 14
Monday to Friday
09h30 to 12h00
Purvis Hall, RM 48
(CRN 867)

Academic Credit: 2

EPIB-644 Digital Pharmacoepidemiology
Substantive Epidemiology 4

david.buckeridge [at] mcgill.ca (Dr. D. Buckeridge)

The increasing availability of new digital resources, such as online media and ontologies, coupled with advances in computing power and analytics, create new opportunities for pharmacoepidemiology. In this course, we will explore through case studies two such opportunities, along with the associated methodological and practical challenges

Prerequisites: Permission of instructor

June 3 and 4
Monday and Tuesday
09h00 to 17h00
Purvis Hall, RM 24
(CRN 868)

Academic Credit: 1

EPIB-645 Confounding in Pharmacoepidemiology: Modern Control Techniques
Substantive Epidemiology 5

robert.platt [at] mcgill.ca (Dr. R. Platt)

This course covers modern methods to control confounding, one of the primary sources of bias in pharmacoepidemiology. Recent years have seen several important developments in methods for confounding control. Most of these methods are based on the propensity score. This course will review the foundations of the propensity score, the high-dimensional propensity score and inverse probability weighting, and the disease risk score. Machine learning methods will be discussed. Worked examples using SAS and R will be discussed.

Prerequisites: Permission of instructor

June 5 and 6
Wednesday and Thursday
09h00 to 17h00
Purvis Hall, RM 24
(CRN 869)

Academic Credit: 1

EPIB-661 PE III: Advanced Pharmacoepidemiology

samy.suissa [at] mcgill.ca (Dr. S. Suissa) / pierre.ernst [at] mcgill.ca (Dr. P. Ernst)

This course is designed to develop skills necessary in the critical appraisal of pharmacoepidemiological studies with a particular focus on advanced methodological issues, study design, analysis and interpretation of results. The course will cover cohort, case-control, nested case-control and within-subject designs, along with various sources of information and selection bias, focussing more specifically on time-risk functions and time-related biases. These issues will be addressed through a review of several published pharmacoepidemiological studies, focussing particularly on studies using computerized health databases.

Prerequisites: EPIb 633, EPIB 631 or Permission of the instructor

June 17 to June 20
Monday to Thursday
09h00 to 17h00
Purvis Hall, RM 24
(CRN 870)

Academic Credits: 2