Fackson Mwale (PhD)

Academic title(s): 
  • Professor, Department of Surgery (Orthopaedic Surgery)
  • James McGill Professor
  • Graduate Program Director Chair
  • Graduate Executive Committee
Fackson Mwale (PhD)
Contact Information
Email address: 
fackson.mwale [at] mcgill.ca
Department: 
Surgery
Division: 
Orthopaedic Surgery
Degree(s): 

PhD, Biochemistry – University of South Carolina, USA

Area(s): 
Basic Sciences
Location: 
Jewish General Hospital
Graduate supervision: 

Currently supervising students

Group: 
Currently Recruiting
M.Sc. Students
Ph.D. Students
Research areas: 
Regenerative Medicine
Translation and Innovation
Medical Technology
Precision Health
Areas of expertise: 

Musculoskeletal biology; intervertebral disc and cartilage biology; translational orthopaedic research; biologic therapeutics.

Current research: 

Dr. Mwale’s research focuses on musculoskeletal biology and translational strategies for intervertebral disc degeneration and osteoarthritis, with emphasis on biologically driven therapeutics, inflammatory and pain-related signaling pathways, and bench-to-clinic translation.

Clinical Interests: 

Musculoskeletal and spinal disorders, Intervertebral disc degeneration Osteoarthritis and chronic pain (research and translational focus)

Areas of interest: 

Translational innovation in orthopaedic surgery; biologic approaches to degenerative musculoskeletal disease; graduate education and research training.

Courses: 
  • EXSU 501 Medical Technology Internship 1
  • EXSU 502 Medical Technology Internship 2
  • EXSU 619 The Hospital Environment 
  • EXSU 620 Surgical Innovation 1 
Biography: 

Dr. Fackson Mwale is a Professor in the Department of Surgery (Orthopaedic Surgery) at McGill University and a James McGill Professor. He serves as Graduate Program Director and Chair of the Graduate Executive Committee, providing leadership in graduate education and research training. Dr. Mwale is a Scientist whose research focuses on musculoskeletal biology, intervertebral disc degeneration, osteoarthritis, and pain and inflammatory mechanisms relevant to orthopaedic disease. His work emphasizes biologically driven and translational approaches aimed at developing novel therapeutic strategies for degenerative musculoskeletal conditions. His research has been supported by peer-reviewed funding from the Canadian Institutes of Health Research (CIHR). He has extensive experience in graduate supervision and mentorship and has served in numerous national and international leadership roles, including Co-Chair of the U.S. National Institutes of Health Musculoskeletal Tissue Engineering Study Section and Editorial Board Member for Biomolecules. He is also the founder and CEO of Intervertech Inc., a company established to support translation of novel therapies for intervertebral disc–related low back pain.

Selected publications: 
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