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Live imaging of meiotic progression of an oocyte from Hfm1–/– female. Photo courtesy of Dr Taketo. PMID: 39545410).

The Rima Sim Laboratory

Our Research

The research activities of my group are focused on the identification of novel genes for various forms of female reproductive failure.

Namely, these forms are recurrent hydatidiform mole, recurrent miscarriage, and infertility. Our work is to elucidate their functions and the mechanisms by which they lead to these conditions.

Our Goals

Our goals are to improve current understanding of the genetics of female reproductive failure and translate the new knowledge into new DNA tests to diagnose these conditions and be able to provide the patients with better management options based on the knowledge of their defective genes.

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