Madeleine Sharp, MD
Assistant Professor
Dr. Madeleine Sharp is a neurologist and clinician-scientist specializing in movements disorders at the Montreal Neurological Institute of McGill University. She received her MD from McGill University, completed her Neurology residency at the University of British Columbia and completed post-doctoral fellowship training at Columbia University. Her research focuses on understanding the cognitive mechanisms underlying cognitive and behavioural symptoms in patients with neurodegenerative disorders, in particular, Parkinson’s disease. The long-term goal is to develop a framework for understanding the many cognitive and behavioural phenotypes of Parkinson’s disease that takes into consideration genetics, pathophysiology, co-morbidities and social factors.
Movement Disorders
Cognitive Neuroscience, Clinical Neuroscience
Lahlou, S., Kaminska, M., Doyon, J., Carrier, J., & Sharp, M. (2024). Sleep spindle density and temporal clustering are associated with sleep-dependent memory consolidation in Parkinson’s disease. Journal of Clinical Sleep Medicine. https://doi.org/10.5664/jcsm.11080
Balit, N., Sun, S., Zhang, Y., & Sharp, M. (2024). Online unsupervised performance-based cognitive testing: A feasible and reliable approach to scalable cognitive phenotyping of Parkinson’s patients. Parkinsonism & Related Disorders, 129, 107183. https://doi.org/10.1016/j.parkreldis.2024.107183
Bogdanov, M., LoParco, S., Otto, A. R., & Sharp, M. (2022). Dopaminergic medication increases motivation to exert cognitive control by reducing subjective effort costs in Parkinson’s patients. Neurobiology of Learning and Memory, 193, 107652. https://doi.org/10.1016/j.nlm.2022.107652
Lahlou, S., Gabitov, E., Owen, L., Shohamy, D., & Sharp, M. (2022). Preserved motor memory in Parkinson’s disease. Neuropsychologia, 167, 108161. https://doi.org/10.1016/j.neuropsychologia.2022.108161
Pilgrim, M. J. D., Ou, Z.-Y. A., & Sharp, M. (2021). Exploring reward-related attention selectivity deficits in Parkinson’s disease. Scientific Reports, 11(1), 18751. https://doi.org/10.1038/s41598-021-97526-7
Sharp, M. E., Duncan, K., Foerde, K., & Shohamy, D. (2020). Dopamine is associated with prioritization of reward-associated memories in Parkinson’s disease. Brain, 143(8), 2519–2531. https://doi.org/10.1093/brain/awaa182